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Showing 1 - 50 of 157 items for (author: vecchia & l)

EMDB-70721:
TMPRSS2 (S441A) bound to the HCoV-NL63 S2'region genetically fused to the HCoV-HKU1 RBD
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-70722:
TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73656:
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73657:
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73786:
HCoV-NL63 S2' peptide bound to TMPRSS2 S441A (complexed with the H1H7 Fab and an anti-kappa-nanobody)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-73787:
SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75233:
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (global refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75694:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75695:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75705:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75721:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75722:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (global refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hk:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hl:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hw:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (Fab local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9opq:
TMPRSS2 (S441A) bound to the HCoV-NL63 S2'region genetically fused to the HCoV-HKU1 RBD
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9opr:
TMPRSS2 S441A in complex with the H1H7 Fab and anti-kappa light chain nanobody
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9yyu:
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (Fab local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9yyv:
SARS-CoV-2 spike trimer in the early fusion intermediate conformation bound to the VN01H1 Fab (S2 local refinement)
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9z3j:
HCoV-NL63 S2' peptide bound to TMPRSS2 S441A (complexed with the H1H7 Fab and an anti-kappa-nanobody)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9z3k:
SARS-CoV-2 S2 trimer stabilized in the early fusion intermediate conformation by circular permutation and clamping by gp41 (E-FICs-v1)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-75697:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-11hn:
SARS-CoV-2 spike S2 trimer stabilized in the early fusion intermediate conformation (E-FICs-v3) bound to C77G12 (S2 local refinement)
Method: single particle / : McCallum M, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-54078:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare G, Thoma NH

EMDB-54157:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2 (Consensus map)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54158:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2 (Focused refinement of BAF part)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

PDB-9rn2:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 2
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare G, Thoma NH

EMDB-54156:
Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2 (Focused refinement of BAF)
Method: single particle / : Domjan D, Weiss J, Cavadini S, Vecchia L, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54056:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 1
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare G, Thoma NH

PDB-9rmc:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL+6 class 1
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare G, Thoma NH

EMDB-54155:
Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2 (Consensus map)
Method: single particle / : Domjan D, Weiss J, Cavadini S, Vecchia L, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54030:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare G, Thoma NH

EMDB-54143:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of ARP module)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54144:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (ATPase part)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54145:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of BAF BASE+ARM+HEAD)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54146:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of nucleosome part)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54152:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focus refinement of nucleosome+OCT4/SOX2 part)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54153:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Consensus map)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-54159:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6 (Focused refinement of nucleosome+OCT4/SOX2 part)
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare GR, Thoma NH

PDB-9rl4:
Structure of BAF in complex with OCT4-SOX2-bound nucleosome - SHL-6
Method: single particle / : Vecchia L, Weiss J, Cavadini S, Kempf G, Kater L, Pathare G, Thoma NH

EMDB-54154:
Structure of BAF-nucleosome complex with OCT4-SOX2 at SHL+6 in ADP-bound state, BAF47 bound to ATPase lobe 2 (Focused refinement of nucleosome and ATPase lobes)
Method: single particle / : Domjan D, Weiss J, Cavadini S, Vecchia L, Kempf G, Kater L, Pathare GR, Thoma NH

EMDB-43813:
VIR-7229 Fab fragment bound the SARS-CoV-2 BA.2.86 spike trimer (local refinement of the BA 2.86 RBD/VIR-7229 VHVL)
Method: single particle / : Park YJ, Tortorici MA, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-43842:
VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement)
Method: single particle / : Tortorici MA, Park YJ, Veelser D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

PDB-9asd:
VIR-7229 Fab fragment bound the SARS-CoV-2 BA.2.86 spike trimer (local refinement of the BA 2.86 RBD/VIR-7229 VHVL)
Method: single particle / : Park YJ, Tortorici MA, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-9au2:
VIR-7229 Fab fragment bound the BA.2.86 spike trimer (global refinement)
Method: single particle / : Tortorici MA, Park YJ, Veelser D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)

EMDB-29530:
SARS-CoV-2 XBB.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-29531:
SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

EMDB-40240:
SARS-CoV-2 BN.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-8fxb:
SARS-CoV-2 XBB.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

PDB-8fxc:
SARS-CoV-2 BQ.1.1 spike RBD bound to the human ACE2 ectodomain and the S309 neutralizing antibody Fab fragment
Method: single particle / : Park YJ, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler D

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