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Showing 1 - 50 of 75 items for (author: pike & acw)

EMDB-56783: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 8694 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56785: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 8500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56787: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 7500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56789: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 6500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56791: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 5500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56793: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 4500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56795: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 3500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56797: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 2500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56799: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 1500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56801: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Dlamini LS, Sauer DB

EMDB-56749: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56784: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 11594 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56786: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56788: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 1500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56790: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 2500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56792: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 3500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56794: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 4500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56796: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 6500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56798: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 5500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56800: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 7500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56802: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 8500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56803: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 9500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56804: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 11500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56805: 
GFP bound to distal DARPin (AHIR dodecamer scaffold system from split dataset with 10500 micrographs)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-56750: 
MBP bound to distal DARPin (AHIR dodecamer scaffold system)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Pike ACW, Sauer DB, Martin M, Dlamini LS

EMDB-56751: 
MBP-maltose bound to distal DARPin (AHIR dodecamer scaffold system)
Method: single particle / : Ferreira DSM, Noble M, Rowland RJ, Fairhead M, Gittins O, von Delft F, Endicott J, Martin M, Pike ACW, Sauer DB, Dlamini LS

EMDB-50668: 
Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the apo inward-open state
Method: single particle / : Ye M, Zhou D, Pike ACW, Wang S, Wang D, Bakshi S, Brooke L, Williams E, Elkins J, Stuart DI, Sauer DB

EMDB-50669: 
Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the arginine-bound inward-occluded state
Method: single particle / : Ye M, Zhou D, Pike ACW, Wang S, Wang D, Bakshi S, Brooke L, Williams E, Elkins J, Stuart DI, Sauer DB

EMDB-50670: 
Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the lysine-bound inward-occluded state
Method: single particle / : Ye M, Zhou D, Pike ACW, Wang S, Wang D, Bakshi S, Brooke L, Williams E, Elkins J, Stuart DI, Sauer DB

EMDB-50671: 
Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the ornithine-bound inward-occluded state
Method: single particle / : Ye M, Zhou D, Pike ACW, Wang S, Wang D, Bakshi S, Brooke L, Williams E, Elkins J, Stuart DI, Sauer DB

EMDB-51568: 
Human adult muscle nAChR in resting state in detergent with alpha-bungarotoxin
Method: single particle / : Li A, Pike ACW, Chi G, Webster R, Maxwell S, Liu W, Beeson D, Sauer DB, Dong YY

EMDB-51569: 
Human adult muscle nAChR in resting state in nanodisc with alpha-bungarotoxin
Method: single particle / : Li A, Pike ACW, Chi G, Webster R, Maxwell S, Liu W, Beeson D, Sauer DB, Dong YY

EMDB-51570: 
Human adult muscle nAChR in desensitised state in nanodisc with 100 uM acetylcholine
Method: single particle / : Li A, Pike ACW, Chi G, Webster R, Maxwell S, Liu W, Beeson D, Sauer DB, Dong YY

EMDB-51571: 
Human adult muscle nAChR in desensitised state in nanodisc with 1 mM acetylcholine
Method: single particle / : Li A, Pike ACW, Chi G, Webster R, Maxwell S, Liu W, Beeson D, Sauer DB, Dong YY

EMDB-51335: 
Cryo-EM structure of KBTBD4 WT-HDAC2 2:1 complex mediated by molecular glue UM171
Method: single particle / : Chen Z, Chi G, Pike ACW, Montes B, Bullock AN

EMDB-51336: 
Cryo-EM map of KBTBD4 WT-HDAC2-CoREST1 2:1:1 complex mediated by molecular glue UM171
Method: single particle / : Chen Z, Chi G, Pike ACW, Montes B, Bullock AN

EMDB-51337: 
Cryo-EM structure of KBTBD4 P313PRR mutant-HDAC2 2:2 complex
Method: single particle / : Chen Z, Chi G, Pike ACW, Montes B, Bullock AN

EMDB-51338: 
Cryo-EM structure of KBTBD4 WT-HDAC2 2:2 complex mediated by molecular glue UM171
Method: single particle / : Chen Z, Chi G, Pike ACW, Montes B, Bullock AN

EMDB-18667: 
Structure of human SPNS2 in LMNG
Method: single particle / : Li HZ, Pike ACW, McKinley G, Mukhopadhyay SMM, Moreau C, Scacioc A, Abrusci P, Borkowska O, Chalk R, Stefanic S, Burgess-Brown N, Duerr KL, Sauer DB

EMDB-18668: 
Structure of human SPNS2 in DDM
Method: single particle / : Li HZ, Pike ACW, McKinley G, Mukhopadhyay SMM, Moreau C, Scacioc A, Abrusci P, Borkowska O, Chalk R, Stefanic S, Burgess-Brown N, Duerr KL, Sauer DB

EMDB-18770: 
Structure of human ceramide synthase 6 (CerS6) bound to C16:0
Method: single particle / : Pascoa TC, Pike ACW, Chi G, Stefanic S, Quigley A, Chalk R, Mukhopadhyay SMM, Venkaya S, Dix C, Moreira T, Tessitore A, Cole V, Chu A, Elkins JM, Pautsch A, Schnapp G, Carpenter EP, Sauer DB

EMDB-18771: 
Structure of human ceramide synthase 6 (CerS6) in complex with N-palmitoyl fumonisin B1
Method: single particle / : Pascoa TC, Pike ACW, Chi G, Stefanic S, Quigley A, Chalk R, Mukhopadhyay SMM, Venkaya S, Dix C, Moreira T, Tessitore A, Cole V, Chu A, Elkins JM, Pautsch A, Schnapp G, Carpenter EP, Sauer DB

EMDB-19869: 
Structure of human ceramide synthase 6 (CerS6) bound to C16:0 (nanobody Nb02)
Method: single particle / : Pascoa TC, Pike ACW, Chi G, Stefanic S, Quigley A, Chalk R, Mukhopadhyay SMM, Venkaya S, Dix C, Moreira T, Tessitore A, Cole V, Chu A, Elkins JM, Pautsch A, Schnapp G, Carpenter EP, Sauer DB

EMDB-17377: 
Structure of human SIT1 (focussed map / refinement)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17378: 
Structure of human SIT1:ACE2 complex (open PD conformation)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17379: 
Structure of human SIT1:ACE2 complex (closed PD conformation)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17380: 
Structure of human SIT1 bound to L-pipecolate (focussed map / refinement)
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17381: 
Structure of human SIT1:ACE2 complex (open PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17382: 
Structure of human SIT1:ACE2 complex (closed PD conformation) bound to L-pipecolate
Method: single particle / : Li HZ, Pike ACW, Chi G, Hansen JS, Lee SG, Rodstrom KEJ, Bushell SR, Speedman D, Evans A, Wang D, He D, Shrestha L, Nasrallah C, Chalk R, Moreira T, MacLean EM, Marsden B, Bountra C, Burgess-Brown NA, Dafforn TR, Carpenter EP, Sauer DB

EMDB-17197: 
Human TPC2 in Complex with Antagonist (S)-SG-094
Method: single particle / : Chi G, Pike ACW, Maclean EM, Li H, Mukhopadhyay SMM, Bohstedt T, Wang D, McKinley G, Fernandez-Cid A, Duerr K
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