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Showing 1 - 50 of 199 items for (author: darst & sa)

EMDB-76371: 
Half-translocated RNA polymerase elemental paused elongation complex, swiveled with ppGpp (ePEC swiveled + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-76372: 
Half-translocated RNA polymerase elemental paused elongation complex, swiveled (ePEC swiveled)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-76373: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL open with ppGpp (ePEC open + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-76374: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL open (ePEC open)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-76375: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed with ppGpp (ePEC semiclosed + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-76376: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed (ePEC semiclosed)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-76377: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL closed with ppGpp (ePEC closed + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-76378: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL closed (ePEC closed)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12eb: 
Half-translocated RNA polymerase elemental paused elongation complex, swiveled with ppGpp (ePEC swiveled + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12ec: 
Half-translocated RNA polymerase elemental paused elongation complex, swiveled (ePEC swiveled)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12ed: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL open with ppGpp (ePEC open + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12ee: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL open (ePEC open)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12ef: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed with ppGpp (ePEC semiclosed + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12eg: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL semiclosed (ePEC semiclosed)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12eh: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL closed with ppGpp (ePEC closed + ppGpp)
Method: single particle / : Mueller AU, Darst SA, Landick R

PDB-12ei: 
Pre-translocated RNA polymerase elemental paused elongation complex, TL closed (ePEC closed)
Method: single particle / : Mueller AU, Darst SA, Landick R

EMDB-75283: 
SemiClosed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a semi-closed active site (closed TL and SI3, open RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75284: 
CBR9379 bound Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75285: 
CBR9379 bound Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75286: 
Closed Mtb-EC: Cryo-EM structure of Mtb RNAP elongation complex (substrate loading mimic) with a closed active site (closed TL and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75287: 
Open Mtb-EC: Cryo-EM structure of Mtb RNAP elongation complex (substrate loading mimic) with an open active site (open TL and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75288: 
SemiClosed Mtb-EC: Cryo-EM structure of Mtb RNAP elongation complex (substrate loading mimic) with a semiclosed active site (closed TL, open RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75289: 
AAP-SO2 bound Open Mtb-EC: Cryo-EM structure of Mtb RNAP elongation complex (substrate loading mimic) with an open active site (open TL and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75279: 
Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75280: 
Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75281: 
Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75282: 
Open3 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-73122: 
De novo initial transcribing RNA polymerase with 2-mer RNA and bound CTP / Michaelis complex (RPitc2+CTP)
Method: single particle / : Mueller AU, Darst SA

EMDB-73123: 
De novo initial transcribing RNA polymerase with pretranslocated 3-mer RNA / product complex (RPitc3)
Method: single particle / : Mueller AU, Darst SA

EMDB-73124: 
de novo initial transcribing RNA polymerase with 5-mer RNA CCAUC (RPitc5a)
Method: single particle / : Mueller AU, Darst SA

EMDB-73125: 
De novo initial transcribing RNA polymerase with 5-mer RNA AUCUA (RPitc5b)
Method: single particle / : Mueller AU, Darst SA

EMDB-73126: 
De novo initial transcribing RNA polymerase with 9-mer RNA (RPitc9)
Method: single particle / : Mueller AU, Darst SA

EMDB-73127: 
De novo initial transcribing RNA polymerase on T7A1 promoter (weak downstream)
Method: single particle / : Mueller AU, Darst SA

EMDB-73128: 
De novo initial transcribing RNA polymerase on T7A1 promoter (empty channel)
Method: single particle / : Mueller AU, Darst SA

EMDB-73130: 
RNA polymerase open complex on T7A1 promoter (RPo)
Method: single particle / : Mueller AU, Darst SA

EMDB-73131: 
De novo initial transcribing RNA polymerase with sigma 70 region 1.1 bound (RPitc-s70_1.1)
Method: single particle / : Mueller AU, Darst SA

EMDB-48776: 
Mfd-bound E.coli RNA polymerase elongation complex + ADP-BeF3 - L1 state
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-48802: 
Mfd-bound E.coli RNA polymerase elongation complex + ADP-BeF3 - L1.5 state
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-47692: 
Off-pathway Mycobacterium tuberculosis transcription initiation promoter complex (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47695: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 7-mer RNA and disordered Beta' Lid element (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47706: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 6-mer RNA and disordered Sigma-A region 4 domain (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47707: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 6-mer RNA and closed Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47708: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 5-mer RNA and open Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47709: 
De Novo Mycobacterium tuberculosis transcription initiation pre-RPO promoter complex with open Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47710: 
De novo backtracked transcription elongation complex of Mycobacterium tuberculosis RNA polymerase on a linear DNA fragment (TEC-Backtracked)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-48574: 
Mycobacterial open-gate proteasome in complex with engineered NtrC1
Method: single particle / : Molina N, Mueller AU, Darst SA

EMDB-48576: 
de novo SigN RNA polymerase open complex (RPo), consensus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48577: 
de novo SigN RNA polymerase open complex (RPo), SigN focus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48578: 
de novo SigN RNA polymerase NTP-bound open complex (RPo+2A), consensus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48579: 
de novo SigN RNA polymerase NTP-bound open complex (RPo+2A), SigN focus map
Method: single particle / : Mueller AU, Darst SA
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