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Showing 1 - 50 of 176 items for (author: darst & sa)

EMDB-73122: 
De novo initial transcribing RNA polymerase with 2-mer RNA and bound CTP / Michaelis complex (RPitc2+CTP)
Method: single particle / : Mueller AU, Darst SA

EMDB-73123: 
De novo initial transcribing RNA polymerase with pretranslocated 3-mer RNA / product complex (RPitc3)
Method: single particle / : Mueller AU, Darst SA

EMDB-73124: 
de novo initial transcribing RNA polymerase with 5-mer RNA CCAUC (RPitc5a)
Method: single particle / : Mueller AU, Darst SA

EMDB-73125: 
De novo initial transcribing RNA polymerase with 5-mer RNA AUCUA (RPitc5b)
Method: single particle / : Mueller AU, Darst SA

EMDB-73126: 
De novo initial transcribing RNA polymerase with 9-mer RNA (RPitc9)
Method: single particle / : Mueller AU, Darst SA

EMDB-73127: 
De novo initial transcribing RNA polymerase on T7A1 promoter (weak downstream)
Method: single particle / : Mueller AU, Darst SA

EMDB-73128: 
De novo initial transcribing RNA polymerase on T7A1 promoter (empty channel)
Method: single particle / : Mueller AU, Darst SA

EMDB-73130: 
RNA polymerase open complex on T7A1 promoter (RPo)
Method: single particle / : Mueller AU, Darst SA

EMDB-73131: 
De novo initial transcribing RNA polymerase with sigma 70 region 1.1 bound (RPitc-s70_1.1)
Method: single particle / : Mueller AU, Darst SA

EMDB-75279: 
Closed Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with a closed active site (closed TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75280: 
Open1 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75281: 
Open2 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-75282: 
Open3 Eco-ePEC: Cryo-EM structure of Eco RNAP his-elemental paused elongation complex with an open active site (open TL, SI3 and RH-FL)
Method: single particle / : Dhingra Y, Darst SA

EMDB-48776: 
Mfd-bound E.coli RNA polymerase elongation complex + ADP-BeF3 - L1 state
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-48802: 
Mfd-bound E.coli RNA polymerase elongation complex + ADP-BeF3 - L1.5 state
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-47692: 
Off-pathway Mycobacterium tuberculosis transcription initiation promoter complex (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47695: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 7-mer RNA and disordered Beta' Lid element (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47706: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 6-mer RNA and disordered Sigma-A region 4 domain (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47707: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 6-mer RNA and closed Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47708: 
De Novo Mycobacterium tuberculosis transcription initiation promoter complex with 5-mer RNA and open Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47709: 
De Novo Mycobacterium tuberculosis transcription initiation pre-RPO promoter complex with open Beta' clamp (RNA Polymerase with Sigma-A, CarD, and RbpA)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-47710: 
De novo backtracked transcription elongation complex of Mycobacterium tuberculosis RNA polymerase on a linear DNA fragment (TEC-Backtracked)
Method: single particle / : Brewer JJ, Campbell EA, Darst SA

EMDB-48574: 
Mycobacterial open-gate proteasome in complex with engineered NtrC1
Method: single particle / : Molina N, Mueller AU, Darst SA

EMDB-48576: 
de novo SigN RNA polymerase open complex (RPo), consensus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48577: 
de novo SigN RNA polymerase open complex (RPo), SigN focus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48578: 
de novo SigN RNA polymerase NTP-bound open complex (RPo+2A), consensus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48579: 
de novo SigN RNA polymerase NTP-bound open complex (RPo+2A), SigN focus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48580: 
de novo SigN RNA polymerase transcription initiation intermediate with pre-catalytic bEBP state (RPi1 open ring), consensus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48581: 
de novo SigN RNA polymerase transcription initiation intermediate with pre-catalytic bEBP state (RPi1 open ring), SigN focus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48582: 
de novo SigN RNA polymerase transcription initiation intermediate with pre-catalytic bEBP state (RPi1 open ring), bEBP focus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48583: 
de novo SigN RNA polymerase transcription initiation intermediate with post-catalytic bEBP state (RPi1 closed ring), consensus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48584: 
de novo SigN RNA polymerase transcription initiation intermediate with post-catalytic bEBP state (RPi1 closed ring), SigN focus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48585: 
de novo SigN RNA polymerase transcription initiation intermediate with post-catalytic bEBP state (RPi1 closed ring), bEBP focus map
Method: single particle / : Mueller AU, Darst SA

EMDB-48586: 
de novo SigN RNA polymerase transcription initiation intermediate with pre-catalytic bEBP state (RPi1 open ring)
Method: single particle / : Mueller AU, Darst SA

EMDB-48587: 
de novo SigN RNA polymerase transcription initiation intermediate with post-catalytic bEBP state (RPi1 closed ring)
Method: single particle / : Mueller AU, Darst SA

EMDB-48588: 
De novo SigN RNA polymerase transcription initiation intermediate with bound SigN-RII
Method: single particle / : Mueller AU, Darst SA

EMDB-48589: 
de novo SigN RNA polymerase open complex (RPo)
Method: single particle / : Mueller AU, Darst SA

EMDB-48590: 
de novo SigN RNA polymerase NTP-bound open complex (RPo+2A)
Method: single particle / : Mueller AU, Darst SA

EMDB-40922: 
Reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA: open duplex DNA (rPTCo)
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-40930: 
Reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA: closed duplex DNA (rPTCc)
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-40931: 
Reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA: unwinding duplex DNA (rPTCi)
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-40943: 
E. coli Sw2/Snf2 ATPase RapA bound to both ADP-AlF3 and reconstituted E. coli RNA polymerase post-termination complex on negatively-supercoiled DNA
Method: single particle / : Brewer JJ, Darst SA, Campbell EA

EMDB-46936: 
RNA-nsp9 bound to the NiRAN domain of the E-RTC with an empty G-pocket
Method: single particle / : Small GI, Darst SA, Campbell EA

EMDB-49420: 
SARS-CoV-2 nsp13(2)-RTC (no detergent)
Method: single particle / : Darst SA, Campbell EA

EMDB-41433: 
Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter
Method: single particle / : Darst SA, Saecker RM, Mueller AU

EMDB-41437: 
Escherichia coli RNA polymerase unwinding intermediate (I1d) at the lambda PR promoter
Method: single particle / : Darst SA, Saecker RM, Mueller AU

EMDB-41439: 
Escherichia coli RNA polymerase unwinding intermediate (I1b) at the lambda PR promoter
Method: single particle / : Darst SA, Saecker RM, Mueller AU

EMDB-41448: 
Escherichia coli RNA polymerase unwinding intermediate (I1c) at the lambda PR promoter
Method: single particle / : Darst SA, Saecker RM, Mueller AU

EMDB-41456: 
Escherichia coli RNA polymerase closed complex intermediate at the lambda PR promoter
Method: single particle / : Darst SA, Saecker RM, Mueller AU

PDB-8to1: 
Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter
Method: single particle / : Darst SA, Saecker RM, Mueller AU
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