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Showing all 11 items for (author: cowan & ad)

EMDB-55257: 
Cryo-EM structure of CRBN bound to 2-[5-chloro-1-(4-piperidyl)indol-4-yl]-2,5-diazaspiro[3.4]octan-6-one in the open conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-55258: 
Cryo-EM structure of CRBN bound to 1-[1-(4-piperidyl)indol-4-yl]hexahydropyrimidine-2,4-dione in the closed conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-55259: 
Cryo-EM structure of CRBN bound to 1-[1-(4-piperidyl)indol-4-yl]hexahydropyrimidine-2,4-dione in the open conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-55057: 
Consensus map of CRBN bound to dihydrouracil ligand in the closed conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-55058: 
Locally refined map of CRBN bound to dihydrouracil ligand in the closed conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-55059: 
Consensus map of CRBN bound to dihydrouracil ligand in the open conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-55060: 
Locally refined map of CRBN TBD bound to dihydrouracil ligand in the open conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-54644: 
Locally refined map of CRBN TBD bound to spirocyclic ligand in the open conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-54624: 
Consensus map of CRBN bound to spirocyclic ligand in the open conformation
Method: single particle / : Cowan AD, Rutter ZJ, McAulay K, Ciulli A

EMDB-54549: 
Ternary complex structure of compound 1 bound to SMARCA2 bromodomain and DCAF16:DDB1deltaBPB
Method: single particle / : Spiteri VA, Nakasone MA, Casement R, Iso K, Cowan AD, Ciulli A

EMDB-17172: 
Ternary structure of intramolecular bivalent glue degrader IBG1 bound to BRD4 and DCAF16:DDB1deltaBPB
Method: single particle / : Cowan AD, Sundaramoorthy R, Nakasone MA, Ciulli A
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