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Structure paper

TitleStructural and Biophysical Methods for the Assessment of Cereblon Binders for PROTACs
Journal, issue, pagesTo Be Published
Publish dateJul 31, 2025 (structure data deposition date)
AuthorsRutter ZJ / Cowan AD / McAulay K / Ciulli A
External linksSearch PubMed
MethodsEM (single particle)
Resolution2.51 - 3.46 Å
Structure data

EMDB-54624: Consensus map of CRBN bound to spirocyclic ligand in the open conformation
Method: EM (single particle) / Resolution: 2.51 Å

EMDB-54644: Locally refined map of CRBN TBD bound to spirocyclic ligand in the open conformation
Method: EM (single particle) / Resolution: 3.46 Å

Source
  • Homo sapiens (human)

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