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Showing all 40 items for (author: cohen & bm)

EMDB-71513:
SARS-CoV-2 Wuhan-Hu-1/BA.1 spike heterotrimer (HT2) with 3-'down' RBDs
Method: single particle / : Fan C, Dam KA, Bjorkman PJ

EMDB-71514:
SARS-CoV-2 Wuhan-Hu-1/BA.1 spike heterotrimer (HT2) with 1-'up' RBD
Method: single particle / : Fan C, Dam KA, Bjorkman PJ

EMDB-71515:
SARS-CoV-2 Wuhan-Hu-1/BA.1/Delta spike heterotrimer (HT3) with 3-'down' RBDs
Method: single particle / : Fan C, Dam KA, Bjorkman PJ

EMDB-71516:
SARS-CoV-2 Wuhan-Hu-1/BA.1/Delta spike heterotrimer (HT3) with 1-'up' RBD
Method: single particle / : Fan C, Dam KA, Bjorkman PJ

EMDB-45193:
V-Shaped, Channel Formed, T2a Nanobody Bound conformation of wild-type human CFTR (sharpened map from cryoSPARC non-uniform refinement)
Method: single particle / : Hunt JF, Paige AS, Cohen BM, Goldberg PM, Wang C, Loughlin BJ, Kappes JC, Yang Z, Jiang F, Govaerts C, Overtus M, Rich Z

EMDB-41895:
(N3Occluded Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41896:
(N3Occluded Local ABC1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41898:
(N3Occluded Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41901:
(N3Occluded Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41902:
(N3Occluded Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42180:
(V17) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41717:
(N3Shifted Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41719:
(N3Shifted Local CORE1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41722:
(N3Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41723:
(N3Shifted Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41724:
(N3 Shifted Local ABC2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41726:
(N3Shifted Composite Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-42177:
(Local CORE2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42178:
(Local ABC2) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-42179:
(Composite) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41900:
(Local CORE2 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Hunt JF, Cohen BM

EMDB-41980:
(Consensus Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-41981:
(Local hNBD1 Map) - "Mechanism of dual pharmacological correction and potentiation of human CFTR"
Method: single particle / : Hunt JF, Wang C, Singh S, Loughlin BJ, Yang Z, Xu H, Veit G, Vorobiev S, Clarke OB, Jiang F, Li Y, Rich Z, Menten ER, Grassucci RA, Wang W, Mezzell A, Fu Z, Wong K, Wetmore DR, Sutton RB, Brouillette CG, Urbatsch IL, Kappes JC, Lukacs GL, Frank J, Cohen BM

EMDB-44246:
Cryo-EM structure of HIV-1 JRFL v6 Env in complex with vaccine-elicited, Membrane Proximal External Region (MPER) directed antibody DH1317.4.
Method: single particle / : Acharya P, Parsons R, Janowska K, Williams WB, Alam M, Haynes BF

EMDB-43931:
CryoEM structure of activated CRAF/MEK/14-3-3 complex with NST-628
Method: single particle / : Quade B, Cohen SE, Huang X

EMDB-43932:
Activated CRAF/MEK heterotetramer from focused refinement of CRAF/MEK/14-3-3 complex
Method: single particle / : Quade B, Cohen SE, Huang X

EMDB-24408:
The Capsid Structure of the ChAdOx1 viral vector/chimpanzee adenovirus Y25
Method: single particle / : Baker AT, Boyd RJ

EMDB-24504:
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)
Method: single particle / : Barnes CO, Jette CA, Bjorkman PJ

EMDB-24505:
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 2)
Method: single particle / : Barnes CO, Jette CA, Bjorkman PJ

PDB-7rkv:
Structure of the SARS-CoV-2 S 6P trimer in complex with neutralizing antibody C118 (State 1)
Method: single particle / : Barnes CO, Jette CA, Bjorkman PJ

EMDB-23693:
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG10-19
Method: single particle / : Barnes CO, Bjorkman PJ

EMDB-23694:
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG1-22
Method: single particle / : Barnes CO, Bjorkman PJ

EMDB-23695:
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG7-15
Method: single particle / : Barnes CO, Bjorkman PJ

EMDB-23696:
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG7-20
Method: single particle / : Barnes CO, Bjorkman PJ

EMDB-23697:
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG1-24
Method: single particle / : Barnes CO, Bjorkman PJ

PDB-7m6e:
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG10-19
Method: single particle / : Barnes CO, Bjorkman PJ

PDB-7m6f:
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG1-22
Method: single particle / : Barnes CO, Bjorkman PJ

PDB-7m6g:
Structure of the SARS-CoV-2 S 6P trimer in complex with the human neutralizing antibody Fab fragment, BG7-15
Method: single particle / : Barnes CO, Bjorkman PJ

PDB-7m6h:
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG7-20
Method: single particle / : Barnes CO, Bjorkman PJ

PDB-7m6i:
Structure of the SARS-CoV-2 S 2P trimer in complex with the human neutralizing antibody Fab fragment, BG1-24
Method: single particle / : Barnes CO, Bjorkman PJ

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Feb 9, 2022. New format data for meta-information of EMDB entries

New format data for meta-information of EMDB entries

  • Version 3 of the EMDB header file is now the official format.
  • The previous official version 1.9 will be removed from the archive.

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Oct 5, 2021. Nobel Prize for mechanically activated and temperature-gated ion channels

Nobel Prize for mechanically activated and temperature-gated ion channels

  • The Nobel Prize in Physiology or Medicine 2021 was awarded jointly to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."
  • EM Navigator can help to find cryo-EM structure data by both pioneers.

External links:The Nobel Prize in Physiology or Medicine 2021 - NobelPrize.org / Structure data by Ardem Patapoutian / Structure data by David Julius

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Related info.:Covid-19 info / Mar 5, 2020. Novel coronavirus structure data

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External links:COVID-19 featured content - PDBj / Molecule of the Month (242)：Coronavirus Proteases

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