1L8P
| Mg-phosphonoacetohydroxamate complex of S39A yeast enolase 1 | Descriptor: | MAGNESIUM ION, PHOSPHONOACETOHYDROXAMIC ACID, enolase 1 | Authors: | Poyner, R.R, Larsen, T.M, Wong, S.W, Reed, G.H. | Deposit date: | 2002-03-21 | Release date: | 2002-04-03 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Functional and structural changes due to a serine to alanine mutation in the active-site flap of enolase. Arch.Biochem.Biophys., 401, 2002
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7M5Z
| Crystal Structure of the MerTK Kinase Domain in Complex with Inhibitor MIPS15692 | Descriptor: | 2-(butylamino)-N-[1-(3-fluoropropyl)piperidin-4-yl]-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}pyrimidine-5-carboxamide, Tyrosine-protein kinase Mer | Authors: | Hermans, S.J, Hancock, N.C, Baell, J.B, Parker, M.W. | Deposit date: | 2021-03-25 | Release date: | 2021-10-06 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.06 Å) | Cite: | Development of [ 18 F]MIPS15692, a radiotracer with in vitro proof-of-concept for the imaging of MER tyrosine kinase (MERTK) in neuroinflammatory disease. Eur.J.Med.Chem., 226, 2021
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