Author results

1BJ8
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THIRD N-TERMINAL DOMAIN OF GP130, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:GP130
Authors:Kernebeck, T., Pflanz, S., Muller-Newen, G., Kurapkat, G., Scheek, R.M., Dijkstra, K., Heinrich, P.C., Wollmer, A., Grzesiek, S., Grotzinger, J.
Deposit date:1998-07-02
Release date:1999-01-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:The signal transducer gp130: solution structure of the carboxy-terminal domain of the cytokine receptor homology region.
Protein Sci., 8, 1999
1B9G
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INSULIN-LIKE-GROWTH-FACTOR-1
Descriptor:PROTEIN (GROWTH FACTOR IGF-1)
Authors:De Wolf, E., Gill, R., Geddes, S., Pitts, J., Wollmer, A., Grotzinger, J.
Deposit date:1999-02-11
Release date:1999-02-23
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of a mini IGF-1.
Protein Sci., 5, 1996
1BZV
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[D-ALAB26]-DES(B27-B30)-INSULIN-B26-AMIDE A SUPERPOTENT SINGLE-REPLACEMENT INSULIN ANALOGUE, NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:INSULIN
Authors:Kurapkat, G., Siedentopf, M., Gattner, H.G., Hagelstein, M., Brandenburg, D., Grotzinger, J., Wollmer, A.
Deposit date:1998-11-04
Release date:1999-05-18
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:The solution structure of a superpotent B-chain-shortened single-replacement insulin analogue.
Protein Sci., 8, 1999
1IZA
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ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN
Descriptor:INSULIN
Authors:Xiao, B., Dodson, G.G.
Deposit date:1992-10-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
J.Mol.Biol., 228, 1992
1IZB
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ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN
Descriptor:INSULIN, ZINC ION
Authors:Xiao, B., Dodson, G.G.
Deposit date:1992-10-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
J.Mol.Biol., 228, 1992
4ER4
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HIGH-RESOLUTION X-RAY ANALYSES OF RENIN INHIBITOR-ASPARTIC PROTEINASE COMPLEXES
Descriptor:ENDOTHIAPEPSIN, H-142
Authors:Foundling, S.I., Watson, F.E., Szelke, M., Blundell, T.L.
Deposit date:1991-01-05
Release date:1991-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes.
Nature, 327, 1987
2ER6
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THE STRUCTURE OF A SYNTHETIC PEPSIN INHIBITOR COMPLEXED WITH ENDOTHIAPEPSIN.
Descriptor:ENDOTHIAPEPSIN, H-256 peptide
Authors:Cooper, J.B., Foundling, S.I., Szelke, M., Blundell, T.L.
Deposit date:1990-10-13
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of a synthetic pepsin inhibitor complexed with endothiapepsin
Eur.J.Biochem., 169, 1987
5ER2
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HIGH-RESOLUTION X-RAY DIFFRACTION STUDY OF THE COMPLEX BETWEEN ENDOTHIAPEPSIN AND AN OLIGOPEPTIDE INHIBITOR. THE ANALYSIS OF THE INHIBITOR BINDING AND DESCRIPTION OF THE RIGID BODY SHIFT IN THE ENZYME
Descriptor:ENDOTHIAPEPSIN, 6-ammonio-N-{[(2R,3R)-3-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-4-cyclohexyl-2-hydroxybutyl](2-methylpropyl)carbamoyl}-L-norleucyl-L-phenylalanine
Authors:Sali, A., Veerapandian, B., Cooper, J.B., Foundling, S.I., Hoover, D.J., Blundell, T.L.
Deposit date:1991-01-02
Release date:1991-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:High-resolution X-ray diffraction study of the complex between endothiapepsin and an oligopeptide inhibitor: the analysis of the inhibitor binding and description of the rigid body shift in the enzyme.
EMBO J., 8, 1989
2ER7
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X-RAY ANALYSES OF ASPARTIC PROTEINASES.III. THREE-DIMENSIONAL STRUCTURE OF ENDOTHIAPEPSIN COMPLEXED WITH A TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN AT 1.6 ANGSTROMS RESOLUTION
Descriptor:ENDOTHIAPEPSIN, TRANSITION-STATE ISOSTERE INHIBITOR OF RENIN, SULFATE ION
Authors:Veerapandian, B., Cooper, J.B., Szelke, M., Blundell, T.L.
Deposit date:1990-11-12
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
J.Mol.Biol., 216, 1990
1ZNI
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INSULIN
Descriptor:INSULIN, ZINC ION, CHLORIDE ION
Authors:Turkenburg, M.G.W., Whittingham, J.L., Dodson, G.G., Dodson, E.J., Xiao, B., Bentley, G.A.
Deposit date:1997-09-23
Release date:1998-01-28
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
1ER8
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor:Endothiapepsin, H-77
Authors:Hemmings, A.M., Veerapandian, B., Szelke, M., Cooper, J.B., Blundell, T.L.
Deposit date:1989-10-16
Release date:1991-10-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
2ER0
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X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES
Descriptor:ENDOTHIAPEPSIN, L364,099
Authors:Cooper, J.B., Foundling, S.I., Boger, J., Blundell, T.L.
Deposit date:1990-10-20
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray studies of aspartic proteinase-statine inhibitor complexes.
Biochemistry, 28, 1989
2ER9
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X-RAY STUDIES OF ASPARTIC PROTEINASE-STATINE INHIBITOR COMPLEXES.
Descriptor:ENDOTHIAPEPSIN, L363,564
Authors:Cooper, J.B., Foundling, S.I., Boger, J., Blundell, T.L.
Deposit date:1990-10-20
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray studies of aspartic proteinase-statine inhibitor complexes.
Biochemistry, 28, 1989
3ER3
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor:ENDOTHIAPEPSIN, 6-ammonio-N-[(2R,4R,5R)-5-{[N-(tert-butoxycarbonyl)-L-phenylalanyl-3-(1H-imidazol-3-ium-4-yl)-L-alanyl]amino}-6-cyclohexyl-4-hydroxy-2-(2-methylpropyl)hexanoyl]-L-norleucylphenylalanine
Authors:Al-Karadaghi, S., Cooper, J.B., Veerapandian, B., Hoover, D., Blundell, T.L.
Deposit date:1991-01-02
Release date:1991-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
3ER5
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor:ENDOTHIAPEPSIN, H-189
Authors:Bailey, D., Veerapandian, B., Cooper, J., Szelke, M., Blundell, T.L.
Deposit date:1991-01-05
Release date:1991-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
Biochem.J., 289 ( Pt 2), 1993
4APE
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor:ENDOTHIAPEPSIN
Authors:Pearl, L.H., Sewell, B.T., Jenkins, J.A., Cooper, J.B., Blundell, T.L.
Deposit date:1986-06-09
Release date:1986-07-14
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The Active Site of Aspartic Proteinases
FEBS Lett., 174, 1984
4ER1
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor:ENDOTHIAPEPSIN, N-[(1R,2R,4R)-1-(cyclohexylmethyl)-2-hydroxy-6-methyl-4-{[(2R)-2-methylbutyl]carbamoyl}heptyl]-3-(1H-imidazol-3-ium-4-yl)-N~2~-[3-naphthalen-1-yl-2-(naphthalen-1-ylmethyl)propanoyl]-L-alaninamide
Authors:Quail, J.W., Cooper, J.B., Szelke, M., Blundell, T.L.
Deposit date:1990-10-14
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The active site of aspartic proteinases
FEBS Lett., 174, 1984
4ER2
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THE ACTIVE SITE OF ASPARTIC PROTEINASES
Descriptor:ENDOTHIAPEPSIN, PEPSTATIN, SULFATE ION
Authors:Bailey, D., Veerapandian, B., Cooper, J.B., Blundell, T.L.
Deposit date:1990-10-20
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:The active site of aspartic proteinases
FEBS Lett., 174, 1984
5ER1
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A RATIONAL APPROACH TO THE DESIGN OF ANTIHYPERTENSIVES. X-RAY STUDIES OF COMPLEXES BETWEEN ASPARTIC PROTEINASES AND AMINOALCOHOL RENIN INHIBITORS
Descriptor:ENDOTHIAPEPSIN, methyl N-[(2S,3S)-3-amino-2-hydroxy-5-methylhexyl]-L-valyl-L-isoleucyl-L-phenylalaninate
Authors:Cooper, J.B., Foundling, S.I., Blundell, T.L.
Deposit date:1990-11-07
Release date:1991-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:A Rational Approach to the Design of Antihypertensives. X-Ray Studies of Complexes between Aspartic Proteinases and Aminoalcohol Renin Inhibitors
Topics in Medicinal Chemistry, 1988