Author results

6QSI
  • Download 6qsi
  • View 6qsi
Molmil generated image of 6qsi
PSEUDOMONAS FLUORESCENS PF-5 THIAMINE DIPHOSPHATE-DEPENDENT 4-HYDROXYBENZOYLFORMATE DECARBOXYLASE
分子名称:Benzoylformate decarboxylase, THIAMINE DIPHOSPHATE, SODIUM ION, ...
著者Wilkinson, R.C., Fulop, V.
登録日2019-02-20
公開日2020-01-08
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Characterization of Thiamine Diphosphate-Dependent 4-Hydroxybenzoylformate Decarboxylase Enzymes fromRhodococcus jostiiRHA1 andPseudomonas fluorescensPf-5 Involved in Degradation of Aryl C2Lignin Degradation Fragments.
Biochemistry, 58, 2019
6PM9
  • Download 6pm9
  • View 6pm9
Molmil generated image of 6pm9
CRYSTAL STRUCTURE OF THE CORE CATALYTIC DOMAIN OF HUMAN O-GLCNACASE BOUND TO MK-8719
分子名称:O-GlcNAcase TIM-barrel domain, O-GlcNAcase stalk domain, (3aR,5S,6S,7R,7aR)-5-(difluoromethyl)-2-(ethylamino)-5,6,7,7a-tetrahydro-3aH-pyrano[3,2-d][1,3]thiazole-6,7-diol
著者Klein, D.J., Selnick, H.G., Duffy, J.L., McEachern, E.J.
登録日2019-07-01
公開日2019-09-18
最終更新日2019-12-11
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Discovery of MK-8719, a Potent O-GlcNAcase Inhibitor as a Potential Treatment for Tauopathies.
J.Med.Chem., 62, 2019
6KR4
  • Download 6kr4
  • View 6kr4
Molmil generated image of 6kr4
CRYSTAL STRUCTURE OF THE LIPRIN-ALPHA3_SAM123/LAR_D1D2 COMPLEX
分子名称:Receptor-type tyrosine-protein phosphatase F, Liprin-alpha-3, TETRAETHYLENE GLYCOL, ...
著者Xie, X., Liang, M., Luo, L., Wei, Z.
登録日2019-08-20
公開日2020-01-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Basis of Liprin-alpha-promoted LAR-RPTP Clustering for Modulation of Phosphatase Activity
Nat Commun, 2020
6IXR
  • Download 6ixr
  • View 6ixr
Molmil generated image of 6ixr
STRUCTURE OF MYO2-GTD IN COMPLEX WITH INP2
分子名称:Myosin-2, Inheritance of peroxisomes protein 2, SULFATE ION
著者Tang, K., Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.854 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IXQ
  • Download 6ixq
  • View 6ixq
Molmil generated image of 6ixq
STRUCTURE OF MYO2-GTD IN COMPLEX WITH SMY1
分子名称:Myosin-2, Kinesin-related protein SMY1
著者Tang, K., Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IXP
  • Download 6ixp
  • View 6ixp
Molmil generated image of 6ixp
STRUCTURE OF MYO2-GTD IN COMPLEX WITH MMR1
分子名称:Myosin-2, Mitochondrial MYO2 receptor-related protein 1
著者Tang, K., Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (2.733 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IXO
  • Download 6ixo
  • View 6ixo
Molmil generated image of 6ixo
APO STRUCTURE OF MYO2-GTD
分子名称:Myosin-2, SULFATE ION, CHLORIDE ION
著者Tang, K., Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2019-07-24
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IVU
  • Download 6ivu
  • View 6ivu
Molmil generated image of 6ivu
SOLUTION STRUCTURE OF THE SIGMA-ANTI-SIGMA FACTOR COMPLEX RSGI1N-SIGI1C FROM CLOSTRIDIUM THERMOCELLUM
分子名称:Anti-sigma-I factor RsgI1, RNA polymerase sigma factor SigI1
著者Wei, Z., Feng, Y.
登録日2018-12-04
公開日2019-05-15
最終更新日2019-07-03
実験手法SOLUTION NMR
主引用文献Alternative sigma I/anti-sigma I factors represent a unique form of bacterial sigma /anti-sigma complex.
Nucleic Acids Res., 47, 2019
6IVS
  • Download 6ivs
  • View 6ivs
Molmil generated image of 6ivs
SOLUTION STRUCTURE OF THE N-TERMINAL DOMAIN OF THE ANTI-SIGMA FACTOR RSGI1 FROM CLOSTRIDIUM THERMOCELLUM
分子名称:Anti-sigma-I factor RsgI1
著者Wei, Z., Feng, Y.
登録日2018-12-04
公開日2019-05-15
最終更新日2019-07-03
実験手法SOLUTION NMR
主引用文献Alternative sigma I/anti-sigma I factors represent a unique form of bacterial sigma /anti-sigma complex.
Nucleic Acids Res., 47, 2019
6IUI
  • Download 6iui
  • View 6iui
Molmil generated image of 6iui
CRYSTAL STRUCTURE OF GIT1 PBD DOMAIN IN COMPLEX WITH PAXILLIN LD4 MOTIF
分子名称:ARF GTPase-activating protein GIT1, Paxillin
著者Liang, M., Wei, Z.
登録日2018-11-28
公開日2019-03-06
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics.
J. Biol. Chem., 294, 2019
6IUH
  • Download 6iuh
  • View 6iuh
Molmil generated image of 6iuh
CRYSTAL STRUCTURE OF GIT1 PBD DOMAIN IN COMPLEX WITH LIPRIN-ALPHA2
分子名称:ARF GTPase-activating protein GIT1, Liprin-alpha-2, IODIDE ION
著者Liang, M., Wei, Z.
登録日2018-11-28
公開日2019-02-20
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics.
J. Biol. Chem., 294, 2019
6FWB
  • Download 6fwb
  • View 6fwb
Molmil generated image of 6fwb
CRYSTAL STRUCTURE OF MAT2A AT 1.79 ANGSTRON RESOLUTION
分子名称:S-adenosylmethionine synthase isoform type-2, SULFATE ION, TETRAETHYLENE GLYCOL, ...
著者Zhou, A., Wei, Z., Bai, J., Wang, H.
登録日2018-03-06
公開日2019-03-27
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes.
Ebiomedicine, 39, 2019
6F4V
  • Download 6f4v
  • View 6f4v
Molmil generated image of 6f4v
CRYSTAL STRUCTURE OF CLEAVED KALLISTATIN COMPLEXED WITH HEPARIN AT 1.8 ANGSTROM RESOLUTION
分子名称:Kallistatin, 1,2-ETHANEDIOL, GLYCEROL, ...
著者Zhou, A., Wei, Z.
登録日2017-11-30
公開日2018-12-12
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of human Kallistatin
To Be Published
6F4U
  • Download 6f4u
  • View 6f4u
Molmil generated image of 6f4u
CRYSTAL STRUCTURE OF REACTIVE LOOP CLEAVED KALLISTATIN AT 1.9 ANGSTROM RESOLUTION
分子名称:Kallistatin, 1,2-ETHANEDIOL, GLYCEROL, ...
著者Zhou, A., Wei, Z., Lin, F.
登録日2017-11-30
公開日2018-12-12
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of human Kallistatin
To Be Published
6D27
  • Download 6d27
  • View 6d27
Molmil generated image of 6d27
CRYSTAL STRUCTURE OF THE PROSTAGLANDIN D2 RECEPTOR CRTH2 WITH CAY10471
分子名称:Prostaglandin D2 receptor 2, Endolysin chimera, SULFATE ION, ...
著者Wang, L., Yao, D., Deepak, K., Liu, H., Gong, W., Fan, H., Wei, Z., Zhang, C.
登録日2018-04-13
公開日2018-10-03
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.738 Å)
主引用文献Structures of the Human PGD2Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition.
Mol. Cell, 72, 2018
6D26
  • Download 6d26
  • View 6d26
Molmil generated image of 6d26
CRYSTAL STRUCTURE OF THE PROSTAGLANDIN D2 RECEPTOR CRTH2 WITH FEVIPIPRANT
分子名称:Prostaglandin D2 receptor 2, Endolysin chimera, fevipiprant, ...
著者Wang, L., Yao, D., Deepak, K., Liu, H., Gong, W., Fan, H., Wei, Z., Zhang, C.
登録日2018-04-13
公開日2018-10-03
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Structures of the Human PGD2Receptor CRTH2 Reveal Novel Mechanisms for Ligand Recognition.
Mol. Cell, 72, 2018
6C1R
  • Download 6c1r
  • View 6c1r
Molmil generated image of 6c1r
CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST AVACOPAN
分子名称:Soluble cytochrome b562, C5a anaphylatoxin chemotactic receptor 1 chimera, PMX53, ...
著者Liu, H., Wang, L., Wei, Z., Zhang, C.
登録日2018-01-05
公開日2018-05-30
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
6C1Q
  • Download 6c1q
  • View 6c1q
Molmil generated image of 6c1q
CRYSTAL STRUCTURE OF HUMAN C5A RECEPTOR IN COMPLEX WITH AN ORTHOSTERIC ANTAGONIST PMX53 AND AN ALLOSTERIC ANTAGONIST NDT9513727
分子名称:Soluble cytochrome b562, C5a anaphylatoxin chemotactic receptor 1 chimera, PMX53, ...
著者Liu, H., Wang, L., Wei, Z., Zhang, C.
登録日2018-01-05
公開日2018-05-30
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Orthosteric and allosteric action of the C5a receptor antagonists.
Nat. Struct. Mol. Biol., 25, 2018
6A68
  • Download 6a68
  • View 6a68
Molmil generated image of 6a68
THE CRYSTAL STRUCTURE OF RAT CALCIUM-DEPENDENT ACTIVATOR PROTEIN FOR SECRETION (CAPS) DAMH DOMAIN
分子名称:Calcium-dependent secretion activator 1, POTASSIUM ION
著者Zhou, H., Wei, Z.Q., Yao, D.Q., Zhang, R.G., Ma, C.
登録日2018-06-26
公開日2019-03-13
最終更新日2019-11-20
実験手法X-RAY DIFFRACTION (2.901 Å)
主引用文献Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.
Cell Rep, 26, 2019
5YAZ
  • Download 5yaz
  • View 5yaz
Molmil generated image of 5yaz
CRYSTAL STRUCTURE OF THE ANKRD DOMAIN OF KANK1
分子名称:KN motif and ankyrin repeat domains 1, ACETATE ION
著者Wei, Z., Pan, W.
登録日2017-09-02
公開日2017-12-20
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.
J. Biol. Chem., 293, 2018
5YAY
  • Download 5yay
  • View 5yay
Molmil generated image of 5yay
CRYSTAL STRUCTURE OF KANK1/KIF21A COMPLEX
分子名称:KN motif and ankyrin repeat domains 1, Kinesin-like protein KIF21A
著者Wei, Z., Pan, W.
登録日2017-09-02
公開日2017-12-20
最終更新日2018-03-07
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insights into ankyrin repeat-mediated recognition of the kinesin motor protein KIF21A by KANK1, a scaffold protein in focal adhesion.
J. Biol. Chem., 293, 2018
5Y7N
  • Download 5y7n
  • View 5y7n
Molmil generated image of 5y7n
CRYSTAL STRUCTURE OF AKR1B10 IN COMPLEX WITH NADP+ AND ANDROST-4-ENE-3-BETA-6-ALPHA-DIOL
分子名称:Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, (3S,6S,8S,9S,10R,13S,14R)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol
著者Hong, Z., Liping, Z., Cuiyun, L., Wei, Z.
登録日2017-08-17
公開日2018-08-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural determinants for the inhibition of AKR1B10 by steroids
To Be Published
5Y4F
  • Download 5y4f
  • View 5y4f
Molmil generated image of 5y4f
CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS R13-24 IN COMPLEX WITH AUTOINHIBITION SEGMENT AI-C
分子名称:Ankyrin-2, CALCIUM ION, ACETATE ION
著者Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M.
登録日2017-08-03
公開日2017-09-13
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5Y4E
  • Download 5y4e
  • View 5y4e
Molmil generated image of 5y4e
CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS R8-14 IN COMPLEX WITH AUTOINHIBITION SEGMENT AI-B
分子名称:Ankyrin-2,Ankyrin-2, GLYCEROL, SULFATE ION
著者Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M.
登録日2017-08-03
公開日2017-09-13
実験手法X-RAY DIFFRACTION (2.341 Å)
主引用文献Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5Y4D
  • Download 5y4d
  • View 5y4d
Molmil generated image of 5y4d
CRYSTAL STRUCTURE OF ANKB ANKYRIN REPEATS IN COMPLEX WITH ANKR/ANKB CHIMERIC AUTOINHIBITION SEGMENT
分子名称:Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION
著者Chen, K., Li, J., Wang, C., Wei, Z., Zhang, M.
登録日2017-08-03
公開日2017-09-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017