Author results

2R2J
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CRYSTAL STRUCTURE OF HUMAN ERP44
Descriptor:Thioredoxin domain-containing protein 4, SUCCINIC ACID, FORMIC ACID
Authors:Wang, L.K., Li, S.J., Sun, F., Wang, C.C.
Deposit date:2007-08-25
Release date:2008-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human ERp44 shows a dynamic functional modulation by its carboxy-terminal tail.
Embo Rep., 2008
1LY1
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STRUCTURE AND MECHANISM OF T4 POLYNUCLEOTIDE KINASE
Descriptor:polynucleotide kinase, SULFATE ION
Authors:Wang, L.K., Lima, C.D., Shuman, S.
Deposit date:2002-06-06
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanism of T4 polynucleotide kinase: an RNA repair enzyme.
EMBO J., 21, 2002
4GP6
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POLYNUCLEOTIDE KINASE
Descriptor:Metallophosphoesterase, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
Authors:Wang, L.K., Das, U., Smith, P., Shuman, S.
Deposit date:2012-08-20
Release date:2012-11-14
Last modified:2012-12-05
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system.
Rna, 18, 2012
4GP7
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POLYNUCLEOTIDE KINASE
Descriptor:Metallophosphoesterase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Wang, L.K., Das, U., Smith, P., Shuman, S.
Deposit date:2012-08-20
Release date:2012-11-14
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanism of the polynucleotide kinase component of the bacterial Pnkp-Hen1 RNA repair system.
Rna, 18, 2012
1D8H
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X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH SULFATE AND MANGANESE IONS.
Descriptor:mRNA TRIPHOSPHATASE CET1, MANGANESE (II) ION, SULFATE ION
Authors:Lima, C.D., Wang, L.K., Shuman, S.
Deposit date:1999-10-24
Release date:1999-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.
Cell(Cambridge,Mass.), 99, 1999
1D8I
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X-RAY CRYSTAL STRUCTURE OF YEAST RNA TRIPHOSPHATASE IN COMPLEX WITH A SULFATE ION.
Descriptor:MRNA TRIPHOSPHATASE CET1, SULFATE ION
Authors:Lima, C.D., Wang, L.K., Shuman, S.
Deposit date:1999-10-24
Release date:1999-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structure and mechanism of yeast RNA triphosphatase: an essential component of the mRNA capping apparatus.
Cell(Cambridge,Mass.), 99, 1999
1S68
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STRUCTURE AND MECHANISM OF RNA LIGASE
Descriptor:RNA Ligase 2, ADENOSINE MONOPHOSPHATE
Authors:Ho, C.K., Wang, L.K., Lima, C.D., Shuman, S.
Deposit date:2004-01-22
Release date:2004-02-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure and mechanism of RNA ligase.
Structure, 12, 2004
2FAO
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN
Descriptor:probable ATP-dependent DNA ligase, SULFATE ION
Authors:Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
Deposit date:2005-12-07
Release date:2006-05-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2FAQ
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN WITH ATP AND MANGANESE
Descriptor:probable ATP-dependent DNA ligase, MANGANESE (II) ION, SULFATE ION, ...
Authors:Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
Deposit date:2005-12-07
Release date:2006-05-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2FAR
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CRYSTAL STRUCTURE OF PSEUDOMONAS AERUGINOSA LIGD POLYMERASE DOMAIN WITH DATP AND MANGANESE
Descriptor:probable ATP-dependent DNA ligase, MANGANESE (II) ION, SULFATE ION, ...
Authors:Zhu, H., Nandakumar, J., Aniukwu, J., Wang, L.K., Glickman, M.S., Lima, C.D., Shuman, S.
Deposit date:2005-12-07
Release date:2006-05-23
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Atomic structure and nonhomologous end-joining function of the polymerase component of bacterial DNA ligase D
Proc.Natl.Acad.Sci.USA, 103, 2006
2IA5
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T4 POLYNUCLEOTIDE KINASE/PHOSPHATASE WITH BOUND SULFATE AND MAGNESIUM.
Descriptor:Polynucleotide kinase, MAGNESIUM ION, SULFATE ION, ...
Authors:Zhu, H., Smith, P.C., Wang, L.K., Lima, C.D., Shuman, S.
Deposit date:2006-09-07
Release date:2007-06-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-function analysis of the 3' phosphatase component of T4 polynucleotide kinase/phosphatase.
Virology, 366, 2007
4JST
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STRUCTURE OF CLOSTRIDIUM THERMOCELLUM POLYNUCLEOTIDE KINASE BOUND TO UTP
Descriptor:Metallophosphoesterase, MAGNESIUM ION, URIDINE 5'-TRIPHOSPHATE, ...
Authors:Das, U., Wang, L.K., Smith, P., Shuman, S.
Deposit date:2013-03-22
Release date:2013-08-28
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system.
Biochemistry, 52, 2013
4JSY
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STRUCTURE OF CLOSTRIDIUM THERMOCELLUM POLYNUCLEOTIDE KINASE BOUND TO GTP
Descriptor:Metallophosphoesterase, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
Authors:Das, U., Wang, L.K., Smith, P., Shuman, S.
Deposit date:2013-03-22
Release date:2013-08-28
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (2.14 Å)
Cite:Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system.
Biochemistry, 52, 2013
4JT2
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STRUCTURE OF CLOSTRIDIUM THERMOCELLUM POLYNUCLEOTIDE KINASE BOUND TO CTP
Descriptor:Metallophosphoesterase, MAGNESIUM ION, CYTIDINE-5'-TRIPHOSPHATE
Authors:Das, U., Wang, L.K., Smith, P., Shuman, S.
Deposit date:2013-03-22
Release date:2013-08-28
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system.
Biochemistry, 52, 2013
4JT4
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STRUCTURE OF CLOSTRIDIUM THERMOCELLUM POLYNUCLEOTIDE KINASE BOUND TO DATP
Descriptor:Metallophosphoesterase, MAGNESIUM ION, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ...
Authors:Das, U., Wang, L.K., Smith, P., Shuman, S.
Deposit date:2013-03-22
Release date:2013-08-28
Last modified:2013-12-18
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Structural and biochemical analysis of the phosphate donor specificity of the polynucleotide kinase component of the bacterial pnkphen1 RNA repair system.
Biochemistry, 52, 2013
4MDE
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STRUCTURE OF BACTERIAL POLYNUCLEOTIDE KINASE PRODUCT COMPLEX BOUND TO GDP AND DNA
Descriptor:Metallophosphoesterase, DNA (5'-D(P*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Shuman, S., Das, U., Wang, L.K., Smith, P., Jacewicz, A.
Deposit date:2013-08-22
Release date:2013-11-06
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition.
Nucleic Acids Res., 42, 2014
4MDF
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STRUCTURE OF BACTERIAL POLYNUCLEOTIDE KINASE MICHAELIS COMPLEX BOUND TO GTP AND DNA
Descriptor:Metallophosphoesterase, DNA (5'-D(*CP*CP*TP*GP*T)-3'), GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Shuman, S., Das, U., Wang, L.K., Smith, P., Jacewicz, A.
Deposit date:2013-08-22
Release date:2013-11-06
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (1.727 Å)
Cite:Structures of bacterial polynucleotide kinase in a Michaelis complex with GTP*Mg2+ and 5'-OH oligonucleotide and a product complex with GDP*Mg2+ and 5'-PO4 oligonucleotide reveal a mechanism of general acid-base catalysis and the determinants of phosphoacceptor recognition.
Nucleic Acids Res., 42, 2014
4QM6
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STRUCTURE OF BACTERIAL POLYNUCLEOTIDE KINASE BOUND TO GTP AND RNA
Descriptor:Metallophosphoesterase, RNA, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Das, U., Wang, L.K., Smith, P., Shuman, S.
Deposit date:2014-06-15
Release date:2014-10-08
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide.
J.Bacteriol., 196, 2014
4QM7
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STRUCTURE OF BACTERIAL POLYNUCLEOTIDE KINASE BOUND TO GTP AND PDNA
Descriptor:Metallophosphoesterase, DNA, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Das, U., Wang, L.K., Smith, P., Shuman, S.
Deposit date:2014-06-15
Release date:2014-10-08
Last modified:2015-02-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structures of bacterial polynucleotide kinase in a michaelis complex with nucleoside triphosphate (NTP)-Mg2+ and 5'-OH RNA and a mixed substrate-product complex with NTP-Mg2+ and a 5'-phosphorylated oligonucleotide.
J.Bacteriol., 196, 2014
4J6O
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CRYSTAL STRUCTURE OF THE PHOSPHATASE DOMAIN OF C. THERMOCELLUM (BACTERIAL) PNKP
Descriptor:Metallophosphoesterase, CITRIC ACID, TRIETHYLENE GLYCOL, ...
Authors:Wang, L., Smith, P., Shuman, S.
Deposit date:2013-02-11
Release date:2013-04-10
Last modified:2013-06-26
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure and mechanism of the 2',3' phosphatase component of the bacterial Pnkp-Hen1 RNA repair system.
Nucleic Acids Res., 41, 2013
3TY5
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CRYSTAL STRUCTURE OF C. THERMOCELLUM PNKP LIGASE DOMAIN IN COMPLEX WITH ATP
Descriptor:Polynucleotide 2',3'-cyclic phosphate phosphodiesterase / polynucleotide 5'-hydroxyl-kinase / polynucleotide 3'-phosphatase, ADENOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Smith, P., Wang, L., Shuman, S.
Deposit date:2011-09-23
Release date:2012-01-25
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TY8
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CRYSTAL STRUCTURE OF C. THERMOCELLUM PNKP LIGASE DOMAIN APO FORM
Descriptor:Polynucleotide 2',3'-cyclic phosphate phosphodiesterase / polynucleotide 5'-hydroxyl-kinase / polynucleotide 3'-phosphatase, GLYCEROL, D(-)-TARTARIC ACID
Authors:Smith, P., Wang, L., Shuman, S.
Deposit date:2011-09-23
Release date:2012-01-25
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family.
Proc.Natl.Acad.Sci.USA, 109, 2012
3TY9
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CRYSTAL STRUCTURE OF C. THERMOCELLUM PNKP LIGASE DOMAIN AMP-ADENYLATE
Descriptor:Polynucleotide 2',3'-cyclic phosphate phosphodiesterase / polynucleotide 5'-hydroxyl-kinase / polynucleotide 3'-phosphatase, ADENOSINE MONOPHOSPHATE, (4S)-2-METHYL-2,4-PENTANEDIOL, ...
Authors:Smith, P., Wang, L., Shuman, S.
Deposit date:2011-09-24
Release date:2012-01-25
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family.
Proc.Natl.Acad.Sci.USA, 109, 2012
1JR7
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CRYSTAL STRUCTURE OF GAB REVEALS OXIDOREDUCTASE FOLD
Descriptor:HYPOTHETICAL 37.4 KDA PROTEIN IN ILEY-GABD INTERGENIC REGION, FE (II) ION
Authors:Lima, C.D., Burley, S.K., New York SGX Research Center for Structural Genomics (NYSGXRC)
Deposit date:2001-08-12
Release date:2001-08-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural genomics: a pipeline for providing structures for the biologist.
Protein Sci., 11, 2002