Author results

1KQR
  • Download 1kqr
  • View 1kqr
Molmil generated image of 1kqr
CRYSTAL STRUCTURE OF THE RHESUS ROTAVIRUS VP4 SIALIC ACID BINDING DOMAIN IN COMPLEX WITH 2-O-METHYL-ALPHA-D-N-ACETYL NEURAMINIC ACID
Descriptor:VP4, SULFATE ION, 2-O-METHYL-5-N-ACETYL-ALPHA-D- NEURAMINIC ACID, ...
Authors:Dormitzer, P.R., Sun, Z.-Y.J., Wagner, G., Harrison, S.C.
Deposit date:2002-01-07
Release date:2002-03-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Rhesus Rotavirus VP4 Sialic Acid Binding Domain has a Galectin Fold with a Novel Carbohydrate Binding Site
Embo J., 21, 2002
4TPW
  • Download 4tpw
  • View 4tpw
Molmil generated image of 4tpw
THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G
Descriptor:Eukaryotic translation initiation factor 4E, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, (2E)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, ...
Authors:Papadopoulos, E., Jenni, S., Wagner, G.
Deposit date:2014-06-09
Release date:2014-08-13
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TQB
  • Download 4tqb
  • View 4tqb
Molmil generated image of 4tqb
THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G
Descriptor:Eukaryotic translation initiation factor 4E, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, (2E)-2-{2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, ...
Authors:Papadopoulos, E., Jenni, S., Wagner, G.
Deposit date:2014-06-10
Release date:2014-08-13
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
6DHB
  • Download 6dhb
  • View 6dhb
Molmil generated image of 6dhb
CRYSTAL STRUCTURE OF THE HUMAN TIM-3 WITH BOUND CALCIUM
Descriptor:Hepatitis A virus cellular receptor 2, CALCIUM ION, BENZOIC ACID, ...
Authors:Gandhi, A.K., Kim, W.M., Huang, Y.H., Bonsor, D., Sundberg, E., Sun, Z.-Y., Petsko, G.A., Kuchroo, V., Blumberg, R.S.
Deposit date:2018-05-19
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3.
Sci Rep, 8, 2018
2RG8
  • Download 2rg8
  • View 2rg8
Molmil generated image of 2rg8
CRYSTAL STRUCTURE OF PROGRAMMED FOR CELL DEATH 4 MIDDLE MA3 DOMAIN
Descriptor:Programmed cell death protein 4, CHLORIDE ION, SODIUM ION
Authors:Garces, R., Suzuki, C., Wagner, G.
Deposit date:2007-10-03
Release date:2008-03-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains.
Proc.Natl.Acad.Sci.Usa, 105, 2008
4TQC
  • Download 4tqc
  • View 4tqc
Molmil generated image of 4tqc
THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G
Descriptor:Eukaryotic translation initiation factor 4E, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, (2S)-3-(4-amino-3-nitrophenyl)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinyl}propanoic acid
Authors:Papadopoulos, E., Jenni, S., Wagner, G.
Deposit date:2014-06-10
Release date:2014-08-13
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MT2
  • Download 4mt2
  • View 4mt2
Molmil generated image of 4mt2
COMPARISON OF THE NMR SOLUTION STRUCTURE AND THE X-RAY CRYSTAL STRUCTURE OF RAT METALLOTHIONEIN-2
Descriptor:METALLOTHIONEIN ISOFORM II, CADMIUM ION, ZINC ION, ...
Authors:Robbins, A.H., Stout, C.D.
Deposit date:1993-02-26
Release date:1993-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
Proc.Natl.Acad.Sci.USA, 89, 1992
1U8B
  • Download 1u8b
  • View 1u8b
Molmil generated image of 1u8b
CRYSTAL STRUCTURE OF THE METHYLATED N-ADA/DNA COMPLEX
Descriptor:5'-D(*TP*AP*AP*AP*TP*T)-3', 5'-D(P*AP*AP*TP*TP*T)-3', 5'-D(P*AP*AP*AP*GP*CP*GP*CP*AP*AP*GP*AP*T)-3', ...
Authors:He, C., Hus, J.-C., Sun, L.J., Zhou, P., Norman, D.P.G., Dotsch, V., Gross, J.D., Lane, W.S., Wagner, G., Verdine, G.L.
Deposit date:2004-08-05
Release date:2005-10-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A methylation-dependent electrostatic switch controls DNA repair and transcriptional activation by E. coli ada.
Mol.Cell, 20, 2005
5BXV
  • Download 5bxv
  • View 5bxv
Molmil generated image of 5bxv
EIF4E COMPLEX
Descriptor:Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE
Authors:Sekiyama, N., Arthanari, H., Papdopoulos, E., Rodriguez-Mias, R.A., Wagner, G., Leger-Abraham, M.
Deposit date:2015-06-09
Release date:2015-07-15
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
Proc.Natl.Acad.Sci.USA, 112, 2015
2QYF
  • Download 2qyf
  • View 2qyf
Molmil generated image of 2qyf
CRYSTAL STRUCTURE OF THE MAD2/P31(COMET)/MAD2-BINDING PEPTIDE TERNARY COMPLEX
Descriptor:Mitotic spindle assembly checkpoint protein MAD2A, MAD2L1-binding protein, peptide
Authors:Tomchick, D.R., Luo, X.
Deposit date:2007-08-14
Release date:2008-01-29
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:p31comet blocks Mad2 activation through structural mimicry.
Cell(Cambridge,Mass.), 131, 2007
2ONT
  • Download 2ont
  • View 2ont
Molmil generated image of 2ont
A SWAPPED DIMER OF THE HIV-1 CAPSID C-TERMINAL DOMAIN
Descriptor:Capsid protein p24
Authors:Ivanov, D., Tsodikov, O.V., Kasanov, J., Ellenberger, T., Wagner, G., Collins, T.
Deposit date:2007-01-24
Release date:2007-02-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Domain-swapped dimerization of the HIV-1 capsid C-terminal domain
Proc.Natl.Acad.Sci.Usa, 104, 2007
5WB5
  • Download 5wb5
  • View 5wb5
Molmil generated image of 5wb5
LEISHMANIA IF4E-1 BOUND TO LEISHMANIA 4E-IP1
Descriptor:Putative eukaryotic translation initiation factor eIF-4E, Uncharacterized protein, DI(HYDROXYETHYL)ETHER
Authors:Leger-Abraham, M., Meleppattu, S., Arthanari, H., Zinoviev, A., Boeszoermenyi, A., Wagner, G., Shapira, M.
Deposit date:2017-06-27
Release date:2018-03-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.
Nucleic Acids Res., 46, 2018
1NUI
  • Download 1nui
  • View 1nui
Molmil generated image of 1nui
CRYSTAL STRUCTURE OF THE PRIMASE FRAGMENT OF BACTERIOPHAGE T7 PRIMASE-HELICASE PROTEIN
Descriptor:DNA primase/helicase, ZINC ION, MAGNESIUM ION
Authors:Kato, M., Ito, T., Wagner, G., Richardson, C.C., Ellenberger, T.
Deposit date:2003-01-31
Release date:2003-05-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Modular Architecture of the Bacteriophage T7 Primase Couples RNA primer Synthesis to DNA Synthesis
Mol.Cell, 11, 2003
1D9K
  • Download 1d9k
  • View 1d9k
Molmil generated image of 1d9k
CRYSTAL STRUCTURE OF COMPLEX BETWEEN D10 TCR AND PMHC I-AK/CA
Descriptor:T-CELL RECEPTOR D10 (ALPHA CHAIN), T-CELL RECEPTOR D10 (BETA CHAIN), MHC I-AK A CHAIN (ALPHA CHAIN), ...
Authors:Reinherz, E.L., Tan, K., Tang, L., Kern, P., Liu, J.-H., Xiong, Y., Hussey, R.E., Smolyar, A., Hare, B., Zhang, R., Joachimiak, A., Chang, H.-C., Wagner, G., Wang, J.-H.
Deposit date:1999-10-28
Release date:1999-12-15
Last modified:2017-02-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:The crystal structure of a T cell receptor in complex with peptide and MHC class II.
Science, 286, 1999
1QA9
  • Download 1qa9
  • View 1qa9
Molmil generated image of 1qa9
STRUCTURE OF A HETEROPHILIC ADHESION COMPLEX BETWEEN THE HUMAN CD2 AND CD58(LFA-3) COUNTER-RECEPTORS
Descriptor:HUMAN CD2 PROTEIN, HUMAN CD58 PROTEIN
Authors:Wang, J.-H., Smolyar, A., Tan, K., Liu, J.-H., Kim, M., Sun, Z.J., Wagner, G., Reinherz, E.L.
Deposit date:1999-04-13
Release date:1999-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors.
Cell(Cambridge,Mass.), 97, 1999
1SLQ
  • Download 1slq
  • View 1slq
Molmil generated image of 1slq
CRYSTAL STRUCTURE OF THE TRIMERIC STATE OF THE RHESUS ROTAVIRUS VP4 MEMBRANE INTERACTION DOMAIN, VP5CT
Descriptor:VP4
Authors:Dormitzer, P.R., Nason, E.B., Prasad, B.V.V., Harrison, S.C.
Deposit date:2004-03-06
Release date:2004-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural rearrangements in the membrane penetration protein of a non-enveloped virus.
Nature, 430, 2004
1A66
  • Download 1a66
  • View 1a66
Molmil generated image of 1a66
SOLUTION NMR STRUCTURE OF THE CORE NFATC1/DNA COMPLEX, 18 STRUCTURES
Descriptor:DNA (5'-D(*CP*GP*AP*GP*GP*AP*AP*AP*AP*TP*TP*G)-3'), DNA (5'-D(*CP*AP*AP*TP*TP*TP*TP*CP*CP*TP*CP*G)-3'), CORE NFATC1
Authors:Zhou, P., Sun, L.J., Doetsch, V., Wagner, G., Verdine, G.L.
Deposit date:1998-03-06
Release date:1998-06-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the core NFATC1/DNA complex.
Cell(Cambridge,Mass.), 92, 1998
1ADN
  • Download 1adn
  • View 1adn
Molmil generated image of 1adn
SOLUTION STRUCTURE OF THE DNA METHYLPHOSPHOTRIESTER REPAIR DOMAIN OF ESCHERICHIA COLI ADA
Descriptor:N-ADA 10, ZINC ION
Authors:Myers, L.C., Verdine, G.L., Wagner, G.
Deposit date:1993-09-30
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the DNA methyl phosphotriester repair domain of Escherichia coli Ada.
Biochemistry, 32, 1993
1AGT
  • Download 1agt
  • View 1agt
Molmil generated image of 1agt
SOLUTION STRUCTURE OF THE POTASSIUM CHANNEL INHIBITOR AGITOXIN 2: CALIPER FOR PROBING CHANNEL GEOMETRY
Descriptor:AGITOXIN 2
Authors:Krezel, A.M., Kasibhatla, C., Hidalgo, P., Mackinnon, R., Wagner, G.
Deposit date:1995-04-14
Release date:1995-07-10
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Solution structure of the potassium channel inhibitor agitoxin 2: caliper for probing channel geometry.
Protein Sci., 4, 1995
1AJE
  • Download 1aje
  • View 1aje
Molmil generated image of 1aje
CDC42 FROM HUMAN, NMR, 20 STRUCTURES
Descriptor:CDC42HS
Authors:Feltham, J.L., Dotsch, V., Raza, S., Manor, D., Cerione, R.A., Sutcliffe, M.J., Wagner, G., Oswald, R.E.
Deposit date:1997-05-02
Release date:1997-11-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Definition of the switch surface in the solution structure of Cdc42Hs.
Biochemistry, 36, 1997
1AJY
  • Download 1ajy
  • View 1ajy
Molmil generated image of 1ajy
STRUCTURE AND MOBILITY OF THE PUT3 DIMER: A DNA PINCER, NMR, 13 STRUCTURES
Descriptor:PUT3, ZINC ION
Authors:Walters, K.J., Dayie, K.T., Reece, R.J., Ptashne, M., Wagner, G.
Deposit date:1997-05-12
Release date:1997-09-17
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and mobility of the PUT3 dimer.
Nat.Struct.Biol., 4, 1997
1AP8
  • Download 1ap8
  • View 1ap8
Molmil generated image of 1ap8
TRANSLATION INITIATION FACTOR EIF4E IN COMPLEX WITH M7GDP, NMR, 20 STRUCTURES
Descriptor:TRANSLATION INITIATION FACTOR EIF4E, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE
Authors:Matsuo, H., Li, H., Mcguire, A.M., Fletcher, M., Gingras, A.C., Sonenberg, N., Wagner, G.
Deposit date:1997-07-25
Release date:1998-01-28
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein.
Nat.Struct.Biol., 4, 1997
1ATX
  • Download 1atx
  • View 1atx
Molmil generated image of 1atx
THREE-DIMENSIONAL STRUCTURE OF THE NEUROTOXIN ATX IA FROM ANEMONIA SULCATA IN AQUEOUS SOLUTION DETERMINED BY NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
Descriptor:ATX IA
Authors:Billeter, M., Widmer, H., Wuthrich, K.
Deposit date:1990-05-14
Release date:1991-04-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Three-dimensional structure of the neurotoxin ATX Ia from Anemonia sulcata in aqueous solution determined by nuclear magnetic resonance spectroscopy.
Proteins, 6, 1989
1AW6
  • Download 1aw6
  • View 1aw6
Molmil generated image of 1aw6
GAL4 (CD), NMR, 24 STRUCTURES
Descriptor:GAL4 (CD), CADMIUM ION
Authors:Baleja, J.D., Wagner, G.
Deposit date:1997-10-10
Release date:1998-04-15
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Refined solution structure of the DNA-binding domain of GAL4 and use of 3J(113Cd,1H) in structure determination.
J.Biomol.NMR, 10, 1997
1BWM
  • Download 1bwm
  • View 1bwm
Molmil generated image of 1bwm
A SINGLE-CHAIN T CELL RECEPTOR
Descriptor:PROTEIN (ALPHA-BETA T CELL RECEPTOR (TCR) (D10))
Authors:Hare, B.J., Wyss, D.F., Reinherz, E.L., Wagner, G.
Deposit date:1998-09-23
Release date:1999-07-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure, specificity and CDR mobility of a class II restricted single-chain T-cell receptor.
Nat.Struct.Biol., 6, 1999