Author results

6MF8
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TCR ALPHA TRANSMEMBRANE DOMAIN
Descriptor:T-cell receptor alpha chain C region
Authors:Brazin, K.N., Reinherz, E.L.
Deposit date:2018-09-10
Release date:2018-12-12
Method:SOLUTION NMR
Cite:The T Cell Antigen Receptor alpha Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations.
Immunity, 49, 2018
6HH0
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YEAST V-ATPASE TRANSMEMBRANE HELIX 7 NMR STRUCTURE IN DPC MICELLES
Descriptor:V-type proton ATPase subunit a, vacuolar isoform
Authors:Zangger, K., Hohlweg, W., Wagner, G.
Deposit date:2018-08-24
Release date:2018-09-12
Last modified:2018-12-19
Method:SOLUTION NMR
Cite:A cation-pi interaction in a transmembrane helix of vacuolar ATPase retains the proton-transporting arginine in a hydrophobic environment.
J. Biol. Chem., 293, 2018
6DHB
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CRYSTAL STRUCTURE OF THE HUMAN TIM-3 WITH BOUND CALCIUM
Descriptor:Hepatitis A virus cellular receptor 2, CALCIUM ION, BENZOIC ACID, ...
Authors:Gandhi, A.K., Kim, W.M., Huang, Y.H., Bonsor, D., Sundberg, E., Sun, Z.-Y., Petsko, G.A., Kuchroo, V., Blumberg, R.S.
Deposit date:2018-05-19
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:High resolution X-ray and NMR structural study of human T-cell immunoglobulin and mucin domain containing protein-3.
Sci Rep, 8, 2018
5WB5
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LEISHMANIA IF4E-1 BOUND TO LEISHMANIA 4E-IP1
Descriptor:Putative eukaryotic translation initiation factor eIF-4E, Uncharacterized protein, DI(HYDROXYETHYL)ETHER
Authors:Leger-Abraham, M., Meleppattu, S., Arthanari, H., Zinoviev, A., Boeszoermenyi, A., Wagner, G., Shapira, M.
Deposit date:2017-06-27
Release date:2018-03-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for LeishIF4E-1 modulation by an interacting protein in the human parasite Leishmania major.
Nucleic Acids Res., 46, 2018
5JS8
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STRUCTURAL MODEL OF A PROTEIN ALPHA SUBUNIT IN COMPLEX WITH GDP OBTAINED WITH SAXS AND NMR RESIDUAL COUPLINGS
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1
Authors:Goricanec, D., Stehle, R., Grigoriu, S., Wagner, G., Hagn, F.
Deposit date:2016-05-07
Release date:2016-06-29
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5JS7
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STRUCTURAL MODEL OF A APO G-PROTEIN ALPHA SUBUNIT DETERMINED WITH NMR RESIDUAL DIPOLAR COUPLINGS AND SAXS
Descriptor:Guanine nucleotide-binding protein G(i) subunit alpha-1
Authors:Goricanec, D., Stehle, R., Grigoriu, S., Wagner, G., Hagn, F.
Deposit date:2016-05-07
Release date:2016-06-29
Last modified:2019-05-08
Method:SOLUTION NMR
Cite:Conformational dynamics of a G-protein alpha subunit is tightly regulated by nucleotide binding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5IJ4
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SOLUTION STRUCTURE OF AN1-TYPE ZINC FINGER DOMAIN FROM CUZ1 (CDC48 ASSOCIATED UBIQUITIN-LIKE/ZINC-FINGER PROTEIN-1)
Descriptor:CDC48-associated ubiquitin-like/zinc finger protein 1, ZINC ION
Authors:Sun, Z.-Y.J., Hanna, J., Wagner, G., Bhanu, M.K., Allan, M., Arthanari, H.
Deposit date:2016-03-01
Release date:2016-10-05
Last modified:2017-09-20
Method:SOLUTION NMR
Cite:Solution Structure of the Cuz1 AN1 Zinc Finger Domain: An Exposed LDFLP Motif Defines a Subfamily of AN1 Proteins.
Plos One, 11, 2016
5H7U
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NMR STRUCTURE OF EIF3 36-163
Descriptor:Eukaryotic translation initiation factor 3 subunit C
Authors:Nagata, T., Obayashi, E.
Deposit date:2016-11-21
Release date:2017-05-31
Method:SOLUTION NMR
Cite:Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5.
Cell Rep, 18, 2017
5GCN
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CATALYTIC DOMAIN OF TETRAHYMENA GCN5 HISTONE ACETYLTRANSFERASE IN COMPLEX WITH COENZYME A
Descriptor:HISTONE ACETYLTRANSFERASE GCN5, COENZYME A
Authors:Lin, Y., Fletcher, C.M., Zhou, J., Allis, C.D., Wagner, G.
Deposit date:1999-03-24
Release date:1999-07-19
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the catalytic domain of GCN5 histone acetyltransferase bound to coenzyme A
Nature, 400, 1999
5BXV
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EIF4E COMPLEX
Descriptor:Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4E-binding protein 1, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE
Authors:Sekiyama, N., Arthanari, H., Papdopoulos, E., Rodriguez-Mias, R.A., Wagner, G., Leger-Abraham, M.
Deposit date:2015-06-09
Release date:2015-07-15
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
Proc.Natl.Acad.Sci.USA, 112, 2015
5A4H
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SOLUTION STRUCTURE OF THE LIPID DROPLET ANCHORING PEPTIDE OF CGI-58 BOUND TO DPC MICELLES
Descriptor:1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5
Authors:Boeszoermenyi, A., Arthanari, H., Wagner, G., Nagy, H.M., Zangger, K., Lindermuth, H., Oberer, M.
Deposit date:2015-06-09
Release date:2015-09-16
Last modified:2015-12-02
Method:SOLUTION NMR
Cite:Structure of a Cgi-58 Motif Provides the Molecular Basis of Lipid Droplet Anchoring.
J.Biol.Chem., 290, 2015
5A3G
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STRUCTURE OF HERPESVIRUS NUCLEAR EGRESS COMPLEX SUBUNIT M50
Descriptor:M50
Authors:Leigh, K.E., Boeszoermenyi, A., Mansueto, M.S., Sharma, M., Filman, D.J., Coen, D.M., Wagner, G., Hogle, J.M., Arthanari, H.
Deposit date:2015-06-01
Release date:2015-07-15
Last modified:2015-08-05
Method:SOLUTION NMR
Cite:Structure of a Herpesvirus Nuclear Egress Complex Subunit Reveals an Interaction Groove that is Essential for Viral Replication
Proc.Natl.Acad.Sci.USA, 112, 2015
4TQC
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THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G
Descriptor:Eukaryotic translation initiation factor 4E, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, (2S)-3-(4-amino-3-nitrophenyl)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinyl}propanoic acid
Authors:Papadopoulos, E., Jenni, S., Wagner, G.
Deposit date:2014-06-10
Release date:2014-08-13
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TQB
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THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G
Descriptor:Eukaryotic translation initiation factor 4E, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, (2E)-2-{2-[4-(4-bromophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, ...
Authors:Papadopoulos, E., Jenni, S., Wagner, G.
Deposit date:2014-06-10
Release date:2014-08-13
Last modified:2014-10-01
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TPW
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THE CO-COMPLEX STRUCTURE OF THE TRANSLATION INITIATION FACTOR EIF4E WITH THE INHIBITOR 4EGI-1 REVEALS AN ALLOSTERIC MECHANISM FOR DISSOCIATING EIF4G
Descriptor:Eukaryotic translation initiation factor 4E, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, (2E)-2-{2-[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene}-3-(2-nitrophenyl)propanoic acid, ...
Authors:Papadopoulos, E., Jenni, S., Wagner, G.
Deposit date:2014-06-09
Release date:2014-08-13
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of the eukaryotic translation initiation factor eIF4E in complex with 4EGI-1 reveals an allosteric mechanism for dissociating eIF4G.
Proc.Natl.Acad.Sci.USA, 111, 2014
4MT2
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COMPARISON OF THE NMR SOLUTION STRUCTURE AND THE X-RAY CRYSTAL STRUCTURE OF RAT METALLOTHIONEIN-2
Descriptor:METALLOTHIONEIN ISOFORM II, CADMIUM ION, ZINC ION, ...
Authors:Robbins, A.H., Stout, C.D.
Deposit date:1993-02-26
Release date:1993-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
Proc.Natl.Acad.Sci.USA, 89, 1992
4D7X
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SOLUTION STRUCTURE OF THE MEDIATOR GALL11 KIX DOMAIN OF C. GLABRATA
Descriptor:MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15
Authors:Boeszoermenyi, A., Wagner, G., Naar, A.M., Arthanari, H.
Deposit date:2014-11-30
Release date:2015-12-09
Last modified:2016-03-02
Method:SOLUTION NMR
Cite:Inhibiting Fungal Multidrug Resistance by Disrupting an Activator-Mediator Interaction.
Nature, 530, 2016
3EGF
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SOLUTION STRUCTURE OF MURINE EPIDERMAL GROWTH FACTOR DETERMINED BY NMR SPECTROSCOPY AND REFINED BY ENERGY MINIMIZATION WITH RESTRAINTS
Descriptor:EPIDERMAL GROWTH FACTOR
Authors:Montelione, G.T., Wuthrich, K., Scheraga, H.A.
Deposit date:1992-08-30
Release date:1994-01-31
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of murine epidermal growth factor determined by NMR spectroscopy and refined by energy minimization with restraints.
Biochemistry, 31, 1992
3CRD
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NMR STRUCTURE OF THE RAIDD CARD DOMAIN, 15 STRUCTURES
Descriptor:RAIDD
Authors:Chou, J.J., Matsuo, H., Duan, H., Wagner, G.
Deposit date:1998-07-24
Release date:1999-02-02
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the RAIDD CARD and model for CARD/CARD interaction in caspase-2 and caspase-9 recruitment.
Cell(Cambridge,Mass.), 94, 1998
2VIL
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REFINED STRUCTURE OF THE ACTIN-SEVERING DOMAIN VILLIN 14T, DETERMINED BY SOLUTION NMR, 11 STRUCTURES
Descriptor:VILLIN 14T
Authors:Markus, M.A., Matsudaira, P., Wagner, G.
Deposit date:1997-01-16
Release date:1997-04-01
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Refined structure of villin 14T and a detailed comparison with other actin-severing domains.
Protein Sci., 6, 1997
2VIK
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REFINED STRUCTURE OF THE ACTIN-SEVERING DOMAIN VILLIN 14T, DETERMINED BY SOLUTION NMR, MINIMIZED AVERAGE STRUCTURE
Descriptor:VILLIN 14T
Authors:Markus, M.A., Matsudaira, P., Wagner, G.
Deposit date:1997-01-16
Release date:1997-04-01
Last modified:2017-11-29
Method:SOLUTION NMR
Cite:Refined structure of villin 14T and a detailed comparison with other actin-severing domains.
Protein Sci., 6, 1997
2RVH
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NMR STRUCTURE OF EIF1
Descriptor:Eukaryotic translation initiation factor eIF-1
Authors:Nagata, T., Obayashi, E., Asano, K.
Deposit date:2015-10-16
Release date:2016-10-26
Last modified:2017-05-31
Method:SOLUTION NMR
Cite:Molecular Landscape of the Ribosome Pre-initiation Complex during mRNA Scanning: Structural Role for eIF3c and Its Control by eIF5
Cell Rep, 18, 2017
2ROQ
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SOLUTION STRUCTURE OF THE THIOLATION-THIOESTERASE DI-DOMAIN OF ENTEROBACTIN SYNTHETASE COMPONENT F
Descriptor:Enterobactin synthetase component F
Authors:Frueh, D.P., Arthanari, H., Koglin, A., Vosburg, D.A., Bennett, A.E., Walsh, C.T., Wagner, G.
Deposit date:2008-04-05
Release date:2008-08-12
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Dynamic thiolation-thioesterase structure of a non-ribosomal peptide synthetase
Nature, 454, 2008
2RON
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THE EXTERNAL THIOESTERASE OF THE SURFACTIN-SYNTHETASE
Descriptor:Surfactin synthetase thioesterase subunit
Authors:Koglin, A., Lohr, F., Bernhard, F., Rogov, V.V., Frueh, D.P., Strieter, E.R., Mofid, M.R., Guentert, P., Wagner, G., Walsh, C.T., Marahiel, M.A., Doetsch, V.
Deposit date:2008-04-04
Release date:2008-08-12
Last modified:2016-10-26
Method:SOLUTION NMR
Cite:Structural basis for the selectivity of the external thioesterase of the surfactin synthetase
Nature, 454, 2008
2RG8
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CRYSTAL STRUCTURE OF PROGRAMMED FOR CELL DEATH 4 MIDDLE MA3 DOMAIN
Descriptor:Programmed cell death protein 4, CHLORIDE ION, SODIUM ION
Authors:Garces, R., Suzuki, C., Wagner, G.
Deposit date:2007-10-03
Release date:2008-03-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains.
Proc.Natl.Acad.Sci.Usa, 105, 2008