Author results

1JDB
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CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIA COLI
Descriptor:CARBAMOYL PHOSPHATE SYNTHETASE, MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Thoden, J.B., Holden, H.M., Wesenberg, G., Raushel, F.M., Rayment, I.
Deposit date:1997-03-25
Release date:1998-06-17
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structure of carbamoyl phosphate synthetase determined to 2.1 A resolution.
Acta Crystallogr.,Sect.D, 55, 1999
1SJA
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X-RAY STRUCTURE OF O-SUCCINYLBENZOATE SYNTHASE COMPLEXED WITH N-ACETYLMETHIONINE
Descriptor:N-acylamino acid racemase, MAGNESIUM ION, N-ACETYLMETHIONINE
Authors:Thoden, J.B., Taylor-Ringia, E.A., Garrett, J.B., Gerlt, J.A., Holden, H.M., Rayment, I.
Deposit date:2004-03-03
Release date:2004-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis
Biochemistry, 43, 2004
1SJB
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X-RAY STRUCTURE OF O-SUCCINYLBENZOATE SYNTHASE COMPLEXED WITH O-SUCCINYLBENZOIC ACID
Descriptor:N-acylamino acid racemase, MAGNESIUM ION, 2-SUCCINYLBENZOATE
Authors:Thoden, J.B., Taylor-Ringia, E.A., Garrett, J.B., Gerlt, J.A., Holden, H.M., Rayment, I.
Deposit date:2004-03-03
Release date:2004-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis
Biochemistry, 43, 2004
1SJC
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X-RAY STRUCTURE OF O-SUCCINYLBENZOATE SYNTHASE COMPLEXED WITH N-SUCCINYL METHIONINE
Descriptor:N-acylamino acid racemase, MAGNESIUM ION, N-SUCCINYL METHIONINE
Authors:Thoden, J.B., Taylor-Ringia, E.A., Garrett, J.B., Gerlt, J.A., Holden, H.M., Rayment, I.
Deposit date:2004-03-03
Release date:2004-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis
Biochemistry, 43, 2004
1SJD
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X-RAY STRUCTURE OF O-SUCCINYLBENZOATE SYNTHASE COMPLEXED WITH N-SUCCINYL PHENYLGLYCINE
Descriptor:N-acylamino acid racemase, N-SUCCINYL PHENYLGLYCINE
Authors:Thoden, J.B., Taylor-Ringia, E.A., Garrett, J.B., Gerlt, J.A., Holden, H.M., Rayment, I.
Deposit date:2004-03-03
Release date:2004-06-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Evolution of Enzymatic Activity in the Enolase Superfamily: Structural Studies of the Promiscuous o-Succinylbenzoate Synthase from Amycolatopsis
Biochemistry, 43, 2004
1A9Y
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UDP-GALACTOSE 4-EPIMERASE MUTANT S124A/Y149F COMPLEXED WITH UDP-GLUCOSE
Descriptor:UDP-GALACTOSE 4-EPIMERASE, SODIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Thoden, J.B., Holden, H.M.
Deposit date:1998-04-14
Release date:1998-10-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry, 37, 1998
1A9Z
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UDP-GALACTOSE 4-EPIMERASE MUTANT S124A/Y149F COMPLEXED WITH UDP-GALACTOSE
Descriptor:UDP-GALACTOSE 4-EPIMERASE, SODIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:Thoden, J.B., Holden, H.M.
Deposit date:1998-04-14
Release date:1998-10-21
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry, 37, 1998
1B6R
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N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE FROM E. COLI
Descriptor:PROTEIN (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE), SULFATE ION
Authors:Thoden, J.B., Kappock, T.J., Stubbe, J., Holden, H.M.
Deposit date:1999-01-17
Release date:1999-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily.
Biochemistry, 38, 1999
1B6S
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STRUCTURE OF N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE
Descriptor:PROTEIN (N5-CARBOXYAMINOIMIDAZOLE RIBONUCLEOTIDE SYNTHETASE), MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Thoden, J.B., Kappock, T.J., Stubbe, J., Holden, H.M.
Deposit date:1999-01-18
Release date:1999-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Three-dimensional structure of N5-carboxyaminoimidazole ribonucleotide synthetase: a member of the ATP grasp protein superfamily.
Biochemistry, 38, 1999
1BXK
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DTDP-GLUCOSE 4,6-DEHYDRATASE FROM E. COLI
Descriptor:PROTEIN (DTDP-GLUCOSE 4,6-DEHYDRATASE), NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Thoden, J.B., Hegeman, A.D., Frey, P.A., Holden, H.M.
Deposit date:1998-10-05
Release date:1998-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Molecular Structure of Dtdp-Glucose 4,6-Dehydratase from E. Coli
Protein Sci.
1BXR
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STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP
Descriptor:CARBAMOYL-PHOSPHATE SYNTHASE, MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Thoden, J.B., Wesenberg, G., Raushel, F.M., Holden, H.M.
Deposit date:1998-10-08
Release date:1999-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Carbamoyl phosphate synthetase: closure of the B-domain as a result of nucleotide binding.
Biochemistry, 38, 1999
1C30
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CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S
Descriptor:CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, MANGANESE (II) ION, ...
Authors:Thoden, J.B., Huang, X., Raushel, F.M., Holden, H.M.
Deposit date:1999-07-24
Release date:1999-12-10
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1C3O
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CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE
Descriptor:CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, MANGANESE (II) ION, ...
Authors:Thoden, J.B., Huang, X., Raushel, F.M., Holden, H.M.
Deposit date:1999-07-28
Release date:1999-12-10
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1CE8
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CARBAMOYL PHOSPHATE SYNTHETASE FROM ESCHERICHIS COLI WITH COMPLEXED WITH THE ALLOSTERIC LIGAND IMP
Descriptor:PROTEIN (CARBAMOYL-PHOSPHATE SYNTHASE), MANGANESE (II) ION, POTASSIUM ION, ...
Authors:Thoden, J.B., Raushel, F.M., Holden, H.M.
Deposit date:1999-03-18
Release date:1999-07-26
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The binding of inosine monophosphate to Escherichia coli carbamoyl phosphate synthetase.
J.Biol.Chem., 274, 1999
1CS0
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CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED AT CYS269 IN THE SMALL SUBUNIT WITH THE TETRAHEDRAL MIMIC L-GLUTAMATE GAMMA-SEMIALDEHYDE
Descriptor:CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, MANGANESE (II) ION, ...
Authors:Thoden, J.B., Huang, X., Raushel, F.M., Holden, H.M.
Deposit date:1999-08-16
Release date:1999-12-10
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1DV1
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STRUCTURE OF BIOTIN CARBOXYLASE (APO)
Descriptor:BIOTIN CARBOXYLASE, PHOSPHATE ION
Authors:Thoden, J.B., Blanchard, C.Z., Holden, H.M., Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
1DV2
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THE STRUCTURE OF BIOTIN CARBOXYLASE, MUTANT E288K, COMPLEXED WITH ATP
Descriptor:BIOTIN CARBOXYLASE, ADENOSINE-5'-TRIPHOSPHATE
Authors:Thoden, J.B., Blanchard, C.Z., Holden, H.M., Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
1EK5
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STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE IN COMPLEX WITH NAD+
Descriptor:UDP-GALACTOSE 4-EPIMERASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
Authors:Thoden, J.B., Wohlers, T.M., Fridovich-Keil, J.L., Holden, H.M.
Deposit date:2000-03-06
Release date:2000-05-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase.
Biochemistry, 39, 2000
1EK6
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STRUCTURE OF HUMAN UDP-GALACTOSE 4-EPIMERASE COMPLEXED WITH NADH AND UDP-GLUCOSE
Descriptor:UDP-GALACTOSE 4-EPIMERASE, MAGNESIUM ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Thoden, J.B., Wohlers, T.M., Fridovich-Keil, J.L., Holden, H.M.
Deposit date:2000-03-06
Release date:2000-05-17
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase.
Biochemistry, 39, 2000
1EYZ
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STRUCTURE OF ESCHERICHIA COLI PURT-ENCODED GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE COMPLEXED WITH MG AND AMPPNP
Descriptor:PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2, MAGNESIUM ION, SODIUM ION, ...
Authors:Thoden, J.B., Firestine, S., Nixon, A., Benkovic, S.J., Holden, H.M.
Deposit date:2000-05-09
Release date:2000-08-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular structure of Escherichia coli PurT-encoded glycinamide ribonucleotide transformylase.
Biochemistry, 39, 2000
1EZ1
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STRUCTURE OF ESCHERICHIA COLI PURT-ENCODED GLYCINAMIDE RIBONUCLEOTIDE TRANSFORMYLASE COMPLEXED WITH MG, AMPPNP, AND GAR
Descriptor:PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE 2, MAGNESIUM ION, ACETATE ION, ...
Authors:Thoden, J.B., Firestine, S., Nixon, A., Benkovic, S.J., Holden, H.M.
Deposit date:2000-05-09
Release date:2000-08-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Molecular structure of Escherichia coli PurT-encoded glycinamide ribonucleotide transformylase.
Biochemistry, 39, 2000
1GUP
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STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP-GALACTOSE
Descriptor:GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, GALACTOSE-URIDINE-5'-DIPHOSPHATE, ZINC ION, ...
Authors:Thoden, J.B., Rayment, I., Holden, H.
Deposit date:1996-10-23
Release date:1997-11-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the H166G site-directed mutant of galactose-1-phosphate uridylyltransferase complexed with either UDP-glucose or UDP-galactose: detailed description of the nucleotide sugar binding site.
Biochemistry, 36, 1997
1GUQ
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STRUCTURE OF NUCLEOTIDYLTRANSFERASE COMPLEXED WITH UDP-GLUCOSE
Descriptor:GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE, ZINC ION, FE (III) ION, ...
Authors:Thoden, J.B., Rayment, I., Holden, H.
Deposit date:1996-10-23
Release date:1997-11-12
Last modified:2013-05-15
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural analysis of the H166G site-directed mutant of galactose-1-phosphate uridylyltransferase complexed with either UDP-glucose or UDP-galactose: detailed description of the nucleotide sugar binding site.
Biochemistry, 36, 1997
1HZJ
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HUMAN UDP-GALACTOSE 4-EPIMERASE: ACCOMMODATION OF UDP-N-ACETYLGLUCOSAMINE WITHIN THE ACTIVE SITE
Descriptor:UDP-GALACTOSE 4-EPIMERASE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Thoden, J.B., Wohlers, T.M., Fridovich-Keil, J.L., Holden, H.M.
Deposit date:2001-01-25
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site.
J.Biol.Chem., 276, 2001
1I3K
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MOLECULAR BASIS FOR SEVERE EPIMERASE-DEFICIENCY GALACTOSEMIA: X-RAY STRUCTURE OF THE HUMAN V94M-SUBSTITUTED UDP-GALACTOSE 4-EPIMERASE
Descriptor:UDP-GLUCOSE 4-EPIMERASE, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Thoden, J.B., Wohlers, T.M., Fridovich-Keil, J.L., Holden, H.M.
Deposit date:2001-02-15
Release date:2001-06-20
Last modified:2019-11-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Molecular basis for severe epimerase deficiency galactosemia. X-ray structure of the human V94m-substituted UDP-galactose 4-epimerase.
J.Biol.Chem., 276, 2001
171916
PDB entries from 2020-12-02