8AHN
 
 | | Sin Nombre virus Gn in complex with Fab SNV-42 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ... | | Authors: | Stass, R, Bowden, T.A. | | Deposit date: | 2022-07-22 | | Release date: | 2023-05-24 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Mechanistic basis for potent neutralization of Sin Nombre hantavirus by a human monoclonal antibody.
Nat Microbiol, 8, 2023
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7NRH
 | | Hantaan virus glycoprotein (Gn) in complex with Fab fragment HTN-Gn1. | | Descriptor: | Envelope polyprotein, Fab fragment HTN-Gn1 Heavy chain, Fab fragment HTN-Gn1 Light chain, ... | | Authors: | Stass, R, Rissanen, I, Bowden, T.A, Huiskonen, J.T. | | Deposit date: | 2021-03-03 | | Release date: | 2021-06-23 | | Last modified: | 2021-09-15 | | Method: | ELECTRON MICROSCOPY (19 Å) | | Cite: | Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen.
Mbio, 12, 2021
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6ZJM
 | | Atomic model of Andes virus glycoprotein spike tetramer generated by fitting into a Tula virus reconstruction | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein, ... | | Authors: | Stass, R, Huiskonen, J.T, Rey, F, Guardado-Calvo, P. | | Deposit date: | 2020-06-29 | | Release date: | 2020-10-14 | | Last modified: | 2020-10-28 | | Method: | ELECTRON MICROSCOPY (11.4 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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7O9S
 | | Hantaan virus Gn in complex with Fab nnHTN-Gn2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab nnHTN-Gn2 Heavy chain, ... | | Authors: | Rissanen, I, Bowden, T.A, Huiskonen, J.T, Stass, R. | | Deposit date: | 2021-04-16 | | Release date: | 2021-06-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen.
Mbio, 12, 2021
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8RVN
 | | Nipah virus (NiV) fusion protein in complex with neutralizing Fab92 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab92 heavy chain, Fab92 light chain, ... | | Authors: | Avanzato, V.A, Stass, R, Duyvesteyn, H.M.E, Bowden, T.A. | | Deposit date: | 2024-02-01 | | Release date: | 2024-09-04 | | Last modified: | 2024-09-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease.
J.Virol., 2024
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7B0A
 | | Puumala virus-like particle glycoprotein spike and lattice contacts model. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ... | | Authors: | Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A. | | Deposit date: | 2020-11-19 | | Release date: | 2020-12-16 | | Last modified: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (13.9 Å) | | Cite: | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020
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7B09
 | | Puumala virus glycoprotein (Gc) in complex with fab fragment P-4G2. | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ... | | Authors: | Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A. | | Deposit date: | 2020-11-19 | | Release date: | 2020-12-16 | | Last modified: | 2021-01-13 | | Method: | ELECTRON MICROSCOPY (13.4 Å) | | Cite: | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020
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7NKS
 | | Structure of the Hantaan virus Gn glycoprotein ectodomain in complex with Fab HTN-Gn1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab HTN-Gn1 heavy chain, ... | | Authors: | Rissanen, I, Bowden, T.A, Huiskonen, J.T, Stass, R. | | Deposit date: | 2021-02-18 | | Release date: | 2021-06-23 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Structural Basis for a Neutralizing Antibody Response Elicited by a Recombinant Hantaan Virus Gn Immunogen.
Mbio, 12, 2021
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5OPG
 | | Structure of the Hantaan virus Gn glycoprotein ectodomain | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, SULFATE ION, ... | | Authors: | Rissanen, I, Stass, R, Zeltina, A, Li, S, Hepojoki, J, Harlos, K, Gilbert, R.J.C, Huiskonen, J.T, Bowden, T.A. | | Deposit date: | 2017-08-09 | | Release date: | 2017-08-23 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural Transitions of the Conserved and Metastable Hantaviral Glycoprotein Envelope.
J. Virol., 91, 2017
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8AWL
 | | Fab RVFV-268 | | Descriptor: | CITRIC ACID, Heavy chain Fab268, Light chain Fab268 | | Authors: | Hulswit, R.J.G, Bowden, T.A, Stass, R. | | Deposit date: | 2022-08-30 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.62 Å) | | Cite: | Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses.
Nat Commun, 14, 2023
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8AWM
 | | RVFV GnH with Fab268 bound | | Descriptor: | Glycoprotein, Heavy chain Fab268, Light chain Fab268 | | Authors: | Hulswit, R.J.G, Bowden, T.A, Stass, R. | | Deposit date: | 2022-08-30 | | Release date: | 2023-09-06 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Multifunctional human monoclonal antibody combination mediates protection against Rift Valley fever virus at low doses.
Nat Commun, 14, 2023
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6Z06
 | | Crystal structure of Puumala virus Gc in complex with Fab 4G2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab 4G2 Heavy chain, ... | | Authors: | Rissanen, I.R, Stass, R, Krumm, S.A, Seow, J, Hulswit, R.J.G, Paesen, G.C, Hepojoki, J, Vapalahti, O, Lundkvist, A, Reynard, O, Volchkov, V, Doores, K.J, Huiskonen, J.T, Bowden, T.A. | | Deposit date: | 2020-05-07 | | Release date: | 2020-12-30 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.5 Å) | | Cite: | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein.
Elife, 9, 2020
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6Y5F
 | | Crystal structure of the envelope glycoprotein prefusion complex of Andes virus - Mutant H953F | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein, PHOSPHATE ION, ... | | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | | Deposit date: | 2020-02-25 | | Release date: | 2020-10-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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6Y6P
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6Y62
 | | Crystal structure of the envelope glycoprotein complex of Maporal virus in a prefusion conformation | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | | Deposit date: | 2020-02-26 | | Release date: | 2020-10-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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6Y68
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6Y6Q
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6YRQ
 | | Crystal structure of the tetramerization domain of the glycoprotein Gn (Andes virus) at pH 4.6 | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | | Deposit date: | 2020-04-20 | | Release date: | 2020-10-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.902 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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6YRB
 | | Crystal structure of the tetramerization domain of the glycoprotein Gn (Andes virus) at pH 7.5 | | Descriptor: | Envelope polyprotein, IODIDE ION, RNA (5'-D(*())-R(P*UP*UP*UP*())-3'), ... | | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | | Deposit date: | 2020-04-20 | | Release date: | 2020-10-14 | | Last modified: | 2020-10-28 | | Method: | X-RAY DIFFRACTION (2.351 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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6Y5W
 | | Crystal structure of the envelope glycoprotein complex of Andes virus in a near postfusion conformation | | Descriptor: | Envelope polyprotein,Envelope polyprotein, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | Authors: | Serris, A, Rey, F.A, Guardado-Calvo, P. | | Deposit date: | 2020-02-26 | | Release date: | 2020-10-14 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (2.55 Å) | | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism.
Cell, 183, 2020
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