Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
7P9K
DownloadVisualize
BU of 7p9k by Molmil
BrxU, GmrSD-family Type IV restriction enzyme
Descriptor: CHLORIDE ION, DUF262 domain-containing protein, GLYCEROL, ...
Authors:Picton, D.M, Luyten, Y, Morgan, R.D, Nelson, A, Smith, D.L, Dryden, D.T.F, Hinton, J.C.D, Blower, T.R.
Deposit date:2021-07-27
Release date:2021-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses.
Nucleic Acids Res., 49, 2021
7P9M
DownloadVisualize
BU of 7p9m by Molmil
BrxU, GmrSD-family Type IV restriction enzyme
Descriptor: CHLORIDE ION, DUF262 domain-containing protein, SULFATE ION
Authors:Picton, D.M, Luyten, Y, Morgan, R.D, Nelson, A, Smith, D.L, Dryden, D.T.F, Hinton, J.C.D, Blower, T.R.
Deposit date:2021-07-27
Release date:2021-12-08
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses.
Nucleic Acids Res., 49, 2021
1AAW
DownloadVisualize
BU of 1aaw by Molmil
THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI
Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE
Authors:Almo, S.C, Smith, D.L, Danishefsky, A.T, Ringe, D.
Deposit date:1993-07-13
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli.
Protein Eng., 7, 1994
1AAM
DownloadVisualize
BU of 1aam by Molmil
THE STRUCTURAL BASIS FOR THE ALTERED SUBSTRATE SPECIFICITY OF THE R292D ACTIVE SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM E. COLI
Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Almo, S.C, Smith, D.L, Danishefsky, A.T, Ringe, D.
Deposit date:1993-07-13
Release date:1993-10-31
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The structural basis for the altered substrate specificity of the R292D active site mutant of aspartate aminotransferase from E. coli.
Protein Eng., 7, 1994
1HFC
DownloadVisualize
BU of 1hfc by Molmil
1.56 ANGSTROM STRUCTURE OF MATURE TRUNCATED HUMAN FIBROBLAST COLLAGENASE
Descriptor: CALCIUM ION, FIBROBLAST COLLAGENASE, METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID, ...
Authors:Spurlino, J.C, Smith, D.L.
Deposit date:1994-09-13
Release date:1995-01-26
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:1.56 A structure of mature truncated human fibroblast collagenase.
Proteins, 19, 1994
1MNC
DownloadVisualize
BU of 1mnc by Molmil
STRUCTURE OF HUMAN NEUTROPHIL COLLAGENASE REVEALS LARGE S1' SPECIFICITY POCKET
Descriptor: CALCIUM ION, METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID, NEUTROPHIL COLLAGENASE, ...
Authors:Stams, T, Spurlino, J.C, Smith, D.L, Rubin, B.
Deposit date:1994-01-12
Release date:1995-02-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of human neutrophil collagenase reveals large S1' specificity pocket.
Nat.Struct.Biol., 1, 1994
1CO4
DownloadVisualize
BU of 1co4 by Molmil
SOLUTION STRUCTURE OF A ZINC DOMAIN CONSERVED IN YEAST COPPER-REGULATED TRANSCRIPTION FACTORS
Descriptor: PROTEIN (ACTIVATOR OF METALLOTHIONEIN 1), ZINC ION
Authors:Turner, R.B, Smith, D.L, Zawrotny, M.E, Summers, M.F, Posewitz, M.C, Winge, D.R.
Deposit date:1999-06-04
Release date:1999-06-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution structure of a zinc domain conserved in yeast copper-regulated transcription factors.
Nat.Struct.Biol., 5, 1998
2AAT
DownloadVisualize
BU of 2aat by Molmil
2.8-ANGSTROMS-RESOLUTION CRYSTAL STRUCTURE OF AN ACTIVE-SITE MUTANT OF ASPARTATE AMINOTRANSFERASE FROM ESCHERICHIA COLI
Descriptor: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, SULFATE ION
Authors:Smith, D, Almo, S.C, Toney, M, Ringe, D.
Deposit date:1989-05-30
Release date:1989-10-15
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:2.8-A-resolution crystal structure of an active-site mutant of aspartate aminotransferase from Escherichia coli.
Biochemistry, 28, 1989
8Q56
DownloadVisualize
BU of 8q56 by Molmil
PglX methyltransferase of Salmonella BREX phage defence system (aka BrxX) bound to inhibitor Ocr
Descriptor: Protein Ocr, S-ADENOSYLMETHIONINE, site-specific DNA-methyltransferase (adenine-specific)
Authors:Went, S.C, Blower, T.R.
Deposit date:2023-08-08
Release date:2024-08-21
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence.
Nat Commun, 15, 2024
8C45
DownloadVisualize
BU of 8c45 by Molmil
PglX methyltransferase from the Salmonella BREX phage defence system (aka BrxX)
Descriptor: S-ADENOSYLMETHIONINE, site-specific DNA-methyltransferase (adenine-specific)
Authors:Blower, T.R, Went, S.C.
Deposit date:2023-01-01
Release date:2024-07-10
Last modified:2024-09-04
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structure and rational engineering of the PglX methyltransferase and specificity factor for BREX phage defence.
Nat Commun, 15, 2024
3AAT
DownloadVisualize
BU of 3aat by Molmil
ACTIVITY AND STRUCTURE OF THE ACTIVE-SITE MUTANTS R386Y AND R386F OF ESCHERICHIA COLI ASPARTATE AMINOTRANSFERASE
Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Danishefsky, A.T, Ringe, D, Petsko, G.A.
Deposit date:1990-12-06
Release date:1992-01-15
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Activity and structure of the active-site mutants R386Y and R386F of Escherichia coli aspartate aminotransferase.
Biochemistry, 30, 1991
1ASA
DownloadVisualize
BU of 1asa by Molmil
THE STRUCTURAL BASIS FOR THE REDUCED ACTIVITY OF THE Y226F(Y225F) ACTIVE SITE MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor: ASPARTATE AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Basis for the Reduced Activity of the Y226F(Y225F) Active Site Mutant of E. Coli Aspartate Aminotransferase
To be Published
8UG3
DownloadVisualize
BU of 8ug3 by Molmil
Crystal structure of KHK-C and compound 23
Descriptor: 2-[(4P)-4-{2-[(2S)-2-methylazetidin-1-yl]-6-(trifluoromethyl)pyrimidin-4-yl}-1H-pyrazol-1-yl]-1-(piperazin-1-yl)ethan-1-one, GLYCEROL, Ketohexokinase, ...
Authors:Durbin, J.D, Guo, S.Y.
Deposit date:2023-10-05
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor.
J.Med.Chem., 66, 2023
8UG1
DownloadVisualize
BU of 8ug1 by Molmil
Crystal structure of KHK-C and compound 13
Descriptor: GLYCEROL, Ketohexokinase, SULFATE ION, ...
Authors:Durbin, J.D, Guo, S.Y.
Deposit date:2023-10-05
Release date:2023-12-06
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Identification of LY3522348: A Highly Selective and Orally Efficacious Ketohexokinase Inhibitor.
J.Med.Chem., 66, 2023
1ASC
DownloadVisualize
BU of 1asc by Molmil
THE STRUCTURAL BASIS FOR THE REDUCED ACTIVITY OF THE D223A(D222A) ACTIVE SITE MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor: ASPARTATE AMINOTRANSFERASE, N-METHYL-4-DEOXY-4-AMINO-PYRIDOXAL-5-PHOSPHATE
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:The Structural Basis for the Reduced Activity of the D223A(D222A) Active Site Mutant of E. Coli Aspartate Aminotransferase
To be Published
1ASF
DownloadVisualize
BU of 1asf by Molmil
THE STRUCTURAL BASIS FOR THE REDUCED ACTIVITY OF THE Y226F(Y225F) ACTIVE SITE MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor: ASPARTATE AMINOTRANSFERASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structural Basis for the Reduced Activity of the Y226F(Y225F) Active Site Mutant of E. Coli Aspartate Aminotransferase
To be Published
1ASB
DownloadVisualize
BU of 1asb by Molmil
THE STRUCTURAL BASIS FOR THE REDUCED ACTIVITY OF THE D223A(D222A) ACTIVE SITE MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor: ASPARTATE AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Structural Basis for the Reduced Activity of the D223A(D222A) Active Site Mutant of E. Coli Aspartate Aminotransferase
To be Published
1ASG
DownloadVisualize
BU of 1asg by Molmil
THE STRUCTURAL BASIS FOR THE REDUCED ACTIVITY OF THE Y226F(Y225F) ACTIVE SITE MUTANT OF E. COLI ASPARTATE AMINOTRANSFERASE
Descriptor: ASPARTATE AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The Structural Basis for the Reduced Activity of the Y226F(Y225F) Active Site Mutant of E. Coli Aspartate Aminotransferase
To be Published
1ASE
DownloadVisualize
BU of 1ase by Molmil
THE STRUCTURE OF WILD TYPE E. COLI ASPARTATE AMINOTRANSFERASE RECONSTITUTED WITH PLP-N-OXIDE
Descriptor: ASPARTATE AMINOTRANSFERASE, MALEIC ACID, PYRIDOXAL-5'-PHOSPHATE-N-OXIDE
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structure of Wild Type E. Coli Aspartate Aminotransferase Reconstituted with Plp-N-Oxide
To be Published
1ASD
DownloadVisualize
BU of 1asd by Molmil
THE STRUCTURE OF WILD TYPE E. COLI ASPARTATE AMINOTRANSFERASE RECONSTITUTED WITH N-MEPLP
Descriptor: ASPARTATE AMINOTRANSFERASE, MALEIC ACID, N-METHYL-PYRIDOXAL-5'-PHOSPHATE
Authors:Schumacher, C, Ringe, D.
Deposit date:1993-08-27
Release date:1994-04-30
Last modified:2024-06-05
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Structure of Wild Type E. Coli Aspartate Aminotransferase Reconstituted with N-Meplp
To be Published
3NYP
DownloadVisualize
BU of 3nyp by Molmil
A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains
Descriptor: 3,6-bis(3-(3'-(R)-fluoropyrrolindino)propionamido)acridine, 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Campbell, N.H, Neidle, S.
Deposit date:2010-07-15
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.179 Å)
Cite:Fluorine in medicinal chemistry: beta-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA.
Org.Biomol.Chem., 9, 2011
3NZ7
DownloadVisualize
BU of 3nz7 by Molmil
A bimolecular anti-parallel-stranded Oxytricha nova telomeric quadruplex in complex with a 3,6-disubstituted acridine ligand containing bis-3-fluoropyrrolidine end side chains
Descriptor: 3,6-bis(3-(3'-(S)-fluoropyrrolindino)propionamido)acridine, 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', POTASSIUM ION
Authors:Campbell, N.H, Neidle, S.
Deposit date:2010-07-16
Release date:2010-08-25
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.1 Å)
Cite:Fluorine in medicinal chemistry: beta-fluorination of peripheral pyrrolidines attached to acridine ligands affects their interactions with G-quadruplex DNA.
Org.Biomol.Chem., 9, 2011

225158

PDB entries from 2024-09-18

PDB statisticsPDBj update infoContact PDBjnumon