Author results

1MKJ
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HUMAN KINESIN MOTOR DOMAIN WITH DOCKED NECK LINKER
Descriptor:KINESIN HEAVY CHAIN, MAGNESIUM ION, SULFATE ION, ...
Authors:Sindelar, C.V., Budny, M.J., Rice, S., Naber, N., Fletterick, R., Cooke, R.
Deposit date:2002-08-29
Release date:2002-10-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Two conformations in the human kinesin power stroke defined by X-ray crystallography and EPR spectroscopy.
Nat.Struct.Biol., 9, 2002
2P4N
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HUMAN MONOMERIC KINESIN (1BG2) AND BOVINE TUBULIN (1JFF) DOCKED INTO THE 9-ANGSTROM CRYO-EM MAP OF NUCLEOTIDE-FREE KINESIN COMPLEXED TO THE MICROTUBULE
Descriptor:Kinesin heavy chain, Tubulin alpha chain, Tubulin beta chain, ...
Authors:Sindelar, C.V., Downing, K.H.
Deposit date:2007-03-12
Release date:2008-07-08
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (9 Å)
Cite:The beginning of kinesin's force-generating cycle visualized at 9-A resolution.
J.Cell Biol., 177, 2007
3DCO
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DROSOPHILA NOD (3DC4) AND BOVINE TUBULIN (1JFF) DOCKED INTO THE 11-ANGSTROM CRYO-EM MAP OF NUCLEOTIDE-FREE NOD COMPLEXED TO THE MICROTUBULE
Descriptor:Kinesin-like protein Nod, Bovine Alpha Tubulin, Bovine Beta Tubulin, ...
Authors:Sindelar, C.V., Cochran, J.C., Kull, F.J.
Deposit date:2008-06-04
Release date:2009-02-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (11 Å)
Cite:ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement.
Cell(Cambridge,Mass.), 136, 2009
5KG8
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RIGOR MYOSIN X CO-COMPLEXED WITH AN ACTIN FILAMENT
Descriptor:Unconventional myosin-X, Actin, alpha skeletal muscle
Authors:Sindelar, C.V., Houdusse, A., Sweeney, L.
Deposit date:2016-06-12
Release date:2016-09-07
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (9.1 Å)
Cite:The myosin X motor is optimized for movement on actin bundles.
Nat Commun, 7, 2016
6PWB
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RIGID BODY FITTING OF FLAGELLIN FLAB, AND FLAGELLAR COILING PROTEINS, FCPA AND FCPB, INTO A 10 ANGSTROM STRUCTURE OF THE ASYMMETRIC FLAGELLAR FILAMENT PURIFIED FROM LEPTOSPIRA BIFLEXA PATOC WT CELLS RESOLVED VIA SUBTOMOGRAM AVERAGING
Descriptor:Flagellin B1 (FlaB1), Flagellar coiling protein A (FcpA), Flagellar coiling protein B (FcpB)
Authors:Gibson, K.H., Sindelar, C.V., Trajtenberg, F., Buschiazzo, A., San Martin, F., Mechaly, A.
Deposit date:2019-07-22
Release date:2020-03-25
Method:ELECTRON MICROSCOPY (9.83 Å)
Cite:An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete.
Elife, 9, 2020
2XRP
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HUMAN DOUBLECORTIN N-DC REPEAT (1MJD) AND MAMMALIAN TUBULIN (1JFF AND 3HKE) DOCKED INTO THE 8-ANGSTROM CRYO-EM MAP OF DOUBLECORTIN- STABILISED MICROTUBULES
Descriptor:TUBULIN BETA-2B CHAIN, TUBULIN ALPHA-1D CHAIN, NEURONAL MIGRATION PROTEIN DOUBLECORTIN, ...
Authors:Fourniol, F.J., Sindelar, C.V., Amigues, B., Clare, D.K., Thomas, G., Perderiset, M., Francis, F., Houdusse, A., Moores, C.A.
Deposit date:2010-09-18
Release date:2010-11-24
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (8.2 Å)
Cite:Template-Free 13-Protofilament Microtubule-Map Assembly Visualized at 8 A Resolution.
J.Cell Biol., 191, 2010
3J8X
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HIGH-RESOLUTION STRUCTURE OF NO-NUCLEOTIDE KINESIN ON MICROTUBULES
Descriptor:Kinesin-1 heavy chain, Tubulin alpha-1B chain, Tubulin beta-2B chain, ...
Authors:Shang, Z., Zhou, K., Xu, C., Csencsits, R., Cochran, J.C., Sindelar, C.V.
Deposit date:2014-11-20
Release date:2014-12-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5 Å)
Cite:High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation.
Elife, 3, 2014
3J8Y
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HIGH-RESOLUTION STRUCTURE OF ATP ANALOG-BOUND KINESIN ON MICROTUBULES
Descriptor:Kinesin-1 heavy chain, Tubulin alpha-1B chain, Tubulin beta-2B chain, ...
Authors:Shang, Z., Zhou, K., Xu, C., Csencsits, R., Cochran, J.C., Sindelar, C.V.
Deposit date:2014-11-20
Release date:2014-12-10
Last modified:2018-07-18
Method:ELECTRON MICROSCOPY (5 Å)
Cite:High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation.
Elife, 3, 2014
4AQV
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MODEL OF HUMAN KINESIN-5 MOTOR DOMAIN (3HQD) AND MAMMALIAN TUBULIN HETERODIMER (1JFF) DOCKED INTO THE 9.7-ANGSTROM CRYO-EM MAP OF MICROTUBULE-BOUND KINESIN-5 MOTOR DOMAIN IN THE AMPPPNP STATE.
Descriptor:TUBULIN ALPHA-1D CHAIN, TUBULIN BETA-2B CHAIN, KINESIN-LIKE PROTEIN KIF11, ...
Authors:Goulet, A., Behnke-Parks, W.M., Sindelar, C.V., Rosenfeld, S.S., Moores, C.A.
Deposit date:2012-04-19
Release date:2012-11-21
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (9.7 Å)
Cite:The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
4AQW
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MODEL OF HUMAN KINESIN-5 MOTOR DOMAIN (1II6, 3HQD) AND MAMMALIAN TUBULIN HETERODIMER (1JFF) DOCKED INTO THE 9.5-ANGSTROM CRYO-EM MAP OF MICROTUBULE-BOUND KINESIN-5 MOTOR DOMAIN IN THE RIGOR STATE.
Descriptor:TUBULIN ALPHA-1D CHAIN, TUBULIN BETA-2B CHAIN, KINESIN-LIKE PROTEIN KIF11, ...
Authors:Goulet, A., Behnke-Parks, W.M., Sindelar, C.V., Rosenfeld, S.S., Moores, C.A.
Deposit date:2012-04-19
Release date:2012-11-21
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (9.5 Å)
Cite:The Structural Basis of Force Generation by the Mitotic Motor Kinesin-5.
J.Biol.Chem., 287, 2012
6C1D
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HIGH-RESOLUTION CRYO-EM STRUCTURES OF ACTIN-BOUND MYOSIN STATES REVEAL THE MECHANISM OF MYOSIN FORCE SENSING
Descriptor:Actin, alpha skeletal muscle, Unconventional myosin-Ib, ...
Authors:Mentes, A., Huehn, A., Liu, X., Zwolak, A., Dominguez, R., Shuman, H., Ostap, E.M., Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1G
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HIGH-RESOLUTION CRYO-EM STRUCTURES OF ACTIN-BOUND MYOSIN STATES REVEAL THE MECHANISM OF MYOSIN FORCE SENSING
Descriptor:Unconventional myosin-Ib, Calmodulin, Actin, ...
Authors:Mentes, A., Huehn, A., Liu, X., Zwolak, A., Dominguez, R., Shuman, H., Ostap, E.M., Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6C1H
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HIGH-RESOLUTION CRYO-EM STRUCTURES OF ACTIN-BOUND MYOSIN STATES REVEAL THE MECHANISM OF MYOSIN FORCE SENSING
Descriptor:Actin, alpha skeletal muscle, Unconventional myosin-Ib, ...
Authors:Mentes, A., Huehn, A., Liu, X., Zwolak, A., Dominguez, R., Shuman, H., Ostap, E.M., Sindelar, C.V.
Deposit date:2018-01-04
Release date:2018-01-31
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6D8C
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CRYO-EM STRUCTURE OF FLNAABD E254K BOUND TO PHALLOIDIN-STABILIZED F-ACTIN
Descriptor:Filamin-A, Actin, alpha skeletal muscle, ...
Authors:Iwamoto, D.V., Huehn, A.R., Simon, B., Huet-Calderwood, C., Baldassarre, M., Sindelar, C.V., Calderwood, D.A.
Deposit date:2018-04-26
Release date:2018-09-19
Last modified:2018-10-17
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of the filamin A actin-binding domain interaction with F-actin.
Nat. Struct. Mol. Biol., 25, 2018
6UBY
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ISOLATED COFILIN BOUND TO AN ACTIN FILAMENT
Descriptor:Actin, alpha skeletal muscle, Cofilin-1, ...
Authors:Huehn, A.R., Bibeau, J.P., Schramm, A.C., Cao, W., De La Cruz, E.M., Sindelar, C.V.
Deposit date:2019-09-13
Release date:2020-01-01
Last modified:2020-02-05
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UC0
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ISOLATED S3D-COFILIN BOUND TO AN ACTIN FILAMENT
Descriptor:Actin, alpha skeletal muscle, Cofilin-1, ...
Authors:Huehn, A.R., Bibeau, J.P., Schramm, A.C., Cao, W., De La Cruz, E.M., Sindelar, C.V.
Deposit date:2019-09-13
Release date:2020-01-01
Last modified:2020-02-05
Method:ELECTRON MICROSCOPY (7.5 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6UC4
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BARBED END SIDE OF A COFILACTIN CLUSTER
Descriptor:Actin, alpha skeletal muscle, Cofilin-1, ...
Authors:Huehn, A.R., Bibeau, J.P., Schramm, A.C., Cao, W., De La Cruz, E.M., Sindelar, C.V.
Deposit date:2019-09-13
Release date:2020-01-01
Last modified:2020-02-05
Method:ELECTRON MICROSCOPY (9.2 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VAO
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HUMAN COFILIN-1 DECORATED ACTIN FILAMENT
Descriptor:Actin, alpha skeletal muscle, Cofilin-1, ...
Authors:Huehn, A.R., Bibeau, J.P., Schramm, A.C., Cao, W., De La Cruz, E.M., Sindelar, C.V.
Deposit date:2019-12-17
Release date:2020-01-08
Last modified:2020-02-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VAU
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BARE ACTIN FILAMENT FROM A PARTIALLY COFILIN-DECORATED SAMPLE
Descriptor:Actin, alpha skeletal muscle, MAGNESIUM ION, ...
Authors:Huehn, A.R., Bibeau, J.P., Schramm, A.C., Cao, W., De La Cruz, E.M., Sindelar, C.V.
Deposit date:2019-12-17
Release date:2020-01-01
Last modified:2020-02-05
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structures of cofilin-induced structural changes reveal local and asymmetric perturbations of actin filaments.
Proc.Natl.Acad.Sci.USA, 117, 2020
6VPO
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CRYO-EM STRUCTURE OF MICROTUBULE-BOUND KLP61F MOTOR DOMAIN IN THE AMPPNP STATE
Descriptor:Tubulin alpha-1A chain, Tubulin beta chain, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T., Wilson-Kubalek, E.M., Nithianantham, S., Debs, G., Sindelar, C.V., Milligan, R., Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
6VPP
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CRYO-EM STRUCTURE OF MICROTUBULE-BOUND KLP61F MOTOR WITH TAIL DOMAIN IN THE NUCLEOTIDE-FREE STATE
Descriptor:Tubulin alpha-1A chain, Tubulin beta chain, Kinesin-like protein Klp61F, ...
Authors:Bodrug, T., Wilson-Kubalek, E.M., Nithianantham, S., Debs, G., Sindelar, C.V., Milligan, R., Al-Bassam, J.
Deposit date:2020-02-04
Release date:2020-02-19
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:The kinesin-5 tail domain directly modulates the mechanochemical cycle of the motor domain for anti-parallel microtubule sliding.
Elife, 9, 2020
5V7X
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CRYSTAL STRUCTURE OF MYOSIN 1B RESIDUES 1-728 WITH BOUND SULFATE AND CALMODULIN
Descriptor:Unconventional myosin-Ib, Calmodulin-1, SULFATE ION
Authors:Zwolak, A., Shuman, H., Dominguez, R., Ostap, E.M.
Deposit date:2017-03-20
Release date:2018-02-28
Method:X-RAY DIFFRACTION (3.141 Å)
Cite:High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6MTI
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SYNAPTOTAGMIN-1 C2A, C2B DOMAINS AND SNARE-PIN PROTEINS (5CCI) INDIVIDUALLY DOCKED INTO CRYO-EM MAP OF C2AB-SNARE COMPLEXES HELICALLY ORGANIZED ON LIPID NANOTUBE SURFACE IN PRESENCE OF MG2+
Descriptor:Synaptotagmin-1, Vesicle-associated membrane protein 2, Syntaxin-1A, ...
Authors:Grushin, K., Wang, J., Coleman, J., Rothman, J., Sindelar, C., Krishnakumar, S.
Deposit date:2018-10-19
Release date:2019-04-24
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (10.4 Å)
Cite:Structural basis for the clamping and Ca2+activation of SNARE-mediated fusion by synaptotagmin.
Nat Commun, 10, 2019
3DC4
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CRYSTAL STRUCTURE OF THE DROSOPHILA KINESIN FAMILY MEMBER NOD IN COMPLEX WITH ADP
Descriptor:Kinesin-like protein Nod, MAGNESIUM ION, ADENOSINE-5'-DIPHOSPHATE
Authors:Cochran, J.C., Mulko, N.K., Kull, F.J.
Deposit date:2008-06-03
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement.
Cell(Cambridge,Mass.), 136, 2009
3DCB
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CRYSTAL STRUCTURE OF THE DROSOPHILA KINESIN FAMILY MEMBER NOD IN COMPLEX WITH AMPPNP
Descriptor:Kinesin-like protein Nod, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Cochran, J.C., Mulko, N.K., Kull, F.J.
Deposit date:2008-06-03
Release date:2009-02-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:ATPase cycle of the nonmotile kinesin NOD allows microtubule end tracking and drives chromosome movement.
Cell(Cambridge,Mass.), 136, 2009
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