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5W4K
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH KLEBSAZOLICIN AND BOUND TO MRNA AND A-, P- AND E-SITE TRNAS AT 2.7A RESOLUTION
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Metelev, M., Osterman, I.A., Ghilarov, D., Khabibullina, N.F., Yakimov, A., Shabalin, K., Utkina, I., Travin, D.Y., Komarova, E.S., Serebryakova, M., Artamonova, T., Khodorkovskii, M., Konevega, A.L., Sergiev, P.V., Severinov, K., Polikanov, Y.S.
Deposit date:2017-06-12
Release date:2017-08-30
Last modified:2019-07-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel.
Nat. Chem. Biol., 13, 2017
5NJ5
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH PHOSPHATE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ZINC ION, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJ9
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH DRVY ANGIOTENSIN FRAGMENT BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ASP-ARG-VAL-TYR, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJA
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH ANGIOTENSIN ANALOGUE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, HIS-PRO-PHE, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJB
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH ACTINONIN BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ZINC ION, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJC
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E (TLDD E263A MUTANT) WITH HEXAPEPTIDE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, VAL-LEU-GLU-ASP-ARG-ILE, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJF
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E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E (TLDD H262A MUTANT) WITH PENTAPEPTIDE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ALA-ALA-ALA-ALA-ALA, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
6GOS
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH PRO-MCCB17 BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-04
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GRG
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH PRO-MCCB17, ADP AND PHOSPHATE BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GRH
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH TRUNCATED PRO-MCCB17 BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GRI
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E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX
Descriptor:Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, Microcin B17-processing protein McbD, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019