Author results

1NKN
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VISUALIZING AN UNSTABLE COILED COIL: THE CRYSTAL STRUCTURE OF AN N-TERMINAL SEGMENT OF THE SCALLOP MYOSIN ROD
Descriptor:S2N51-GCN4
Authors:Li, Y., Brown, J.H., Reshetnikova, L., Blazsek, A., Farkas, L., Nyitray, L., Cohen, C.
Deposit date:2003-01-03
Release date:2003-07-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Visualization of an unstable coiled coil from the scallop myosin rod
Nature, 424, 2003
2BL0
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PHYSARUM POLYCEPHALUM MYOSIN II REGULATORY DOMAIN
Descriptor:MAJOR PLASMODIAL MYOSIN HEAVY CHAIN, MYOSIN REGULATORY LIGHT CHAIN, CALCIUM ION
Authors:Debreczeni, J.E., Farkas, L., Harmat, V., Nyitray, L.
Deposit date:2005-02-23
Release date:2005-10-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Evidence for Non-Canonical Binding of Ca2+ to a Canonical EF-Hand of a Conventional Myosin.
J.Biol.Chem., 280, 2005
2OTG
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RIGOR-LIKE STRUCTURES OF MUSCLE MYOSINS REVEAL KEY MECHANICAL ELEMENTS IN THE TRANSDUCTION PATHWAYS OF THIS ALLOSTERIC MOTOR
Descriptor:Myosin heavy chain, Myosin regulatory light chain, Myosin essential light chain, ...
Authors:Yang, Y., Gourinath, S., Kovacs, M., Nyitray, L., Reutzel, R., Himmel, D.M., O'Neall-Hennessey, E., Reshetnikova, L., Szent-Gyorgyi, A.G., Brown, J.H., Cohen, C.
Deposit date:2007-02-08
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.12 Å)
Cite:Rigor-like Structures from Muscle Myosins Reveal Key Mechanical Elements in the Transduction Pathways of This Allosteric Motor.
Structure, 15, 2007
2XQQ
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE (AC-SRGTQTE).
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, SAC-ARG-GLY-THR-GLN-THR-GLU, ...
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-09-07
Release date:2011-05-04
Last modified:2013-11-20
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:Directed Evolution Reveals the Binding Motif Preference of the Lc8/Dynll Hub Protein and Predicts Large Numbers of Novel Binders in the Human Proteome
Plos One, 6, 2011
3I5F
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CRYSTAL STRUCTURE OF SQUID MG.ADP MYOSIN S1
Descriptor:Myosin heavy chain isoform A, Myosin regulatory light chain LC-2, mantle muscle, ...
Authors:Yang, Y., Gourinath, S., Kovacs, M., Nyitray, L., Reutzel, R., Himmel, D.M., O'Neall-Hennessey, E., Reshetnikova, L., Szent-Gyorgyi, A.G., Brown, J.H., Cohen, C.
Deposit date:2009-07-05
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
3I5G
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CRYSTAL STRUCTURE OF RIGOR-LIKE SQUID MYOSIN S1
Descriptor:Myosin heavy chain isoform A, Myosin regulatory light chain LC-2, mantle muscle, ...
Authors:Yang, Y., Gourinath, S., Kovacs, M., Nyitray, L., Reutzel, R., Himmel, D.M., O'Neall-Hennessey, E., Reshetnikova, L., Szent-Gyorgyi, A.G., Brown, J.H., Cohen, C.
Deposit date:2009-07-05
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
3I5H
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THE CRYSTAL STRUCTURE OF RIGOR LIKE SQUID MYOSIN S1 IN THE ABSENCE OF NUCLEOTIDE
Descriptor:Myosin heavy chain isoform A, Myosin regulatory light chain LC-2, mantle muscle, ...
Authors:Yang, Y., Gourinath, S., Kovacs, M., Nyitray, L., Reutzel, R., Himmel, D.M., O'Neall-Hennessey, E., Reshetnikova, L., Szent-Gyorgyi, A.G., Brown, J.H., Cohen, C.
Deposit date:2009-07-05
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
3I5I
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THE CRYSTAL STRUCTURE OF SQUID MYOSIN S1 IN THE PRESENCE OF SO4 2-
Descriptor:Myosin heavy chain isoform A, Myosin regulatory light chain LC-2, mantle muscle, ...
Authors:Yang, Y., Gourinath, S., Kovacs, M., Nyitray, L., Reutzel, R., Himmel, D.M., O'Neall-Hennessey, E., Reshetnikova, L., Szent-Gyorgyi, A.G., Brown, J.H., Cohen, C.
Deposit date:2009-07-05
Release date:2009-07-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Rigor-like structures from muscle myosins reveal key mechanical elements in the transduction pathways of this allosteric motor.
Structure, 15, 2007
3P8M
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HUMAN DYNEIN LIGHT CHAIN (DYNLL2) IN COMPLEX WITH AN IN VITRO EVOLVED PEPTIDE DIMERIZED BY LEUCINE ZIPPER
Descriptor:Dynein light chain 2, General control protein GCN4
Authors:Rapali, P., Radnai, L., Suveges, D., Hetenyi, C., Harmat, V., Tolgyesi, F., Wahlgren, W.Y., Katona, G., Nyitray, L., Pal, G.
Deposit date:2010-10-14
Release date:2011-08-31
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Directed evolution reveals the binding motif preference of the LC8/DYNLL hub protein and predicts large numbers of novel binders in the human proteome.
Plos One, 6, 2011
3ZWH
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CA2+-BOUND S100A4 C3S, C81S, C86S AND F45W MUTANT COMPLEXED WITH MYOSIN IIA
Descriptor:PROTEIN S100-A4, MYOSIN-9, CALCIUM ION, ...
Authors:Kiss, B., Duelli, A., Radnai, L., Kekesi, A.K., Katona, G., Nyitray, L.
Deposit date:2011-07-31
Release date:2012-04-04
Last modified:2013-11-27
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Crystal Structure of the S100A4-Nonmuscle Myosin Iia Tail Fragment Complex Reveals an Asymmetric Target Binding Mechanism.
Proc.Natl.Acad.Sci.USA, 109, 2012
4CFQ
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CA-BOUND TRUNCATED (DELTA13C) AND C3S, C81S AND C86S MUTATED S100A4 COMPLEXED WITH NON-MUSCLE MYOSIN IIA
Descriptor:PROTEIN S100-A4, MYOSIN-9, CALCIUM ION
Authors:Duelli, A., Kiss, B., Lundholm, I., Bodor, A., Radnai, L., Petoukhov, M., Svergun, D., Nyitray, L., Katona, G.
Deposit date:2013-11-19
Release date:2014-05-07
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 Through Conformational Activation.
Plos One, 9, 2014
4CFR
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CA-BOUND S100A4 C3S, C81S, C86S AND F45W MUTANT COMPLEXED WITH NON- MUSCLE MYOSIN IIA
Descriptor:PROTEIN S100-A4, MYOSIN-9, CALCIUM ION
Authors:Duelli, A., Kiss, B., Lundholm, I., Bodor, A., Radnai, L., Petoukhov, M., Svergun, D., Nyitray, L., Katona, G.
Deposit date:2013-11-19
Release date:2014-05-07
Last modified:2014-05-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 Through Conformational Activation.
Plos One, 9, 2014
4D07
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DYNLL2 DYNEIN LIGHT CHAIN BINDS TO AN EXTENDED, UNSTRUCTURED LINEAR MOTIF OF MYOSIN 5A TAIL
Descriptor:DYNEIN LIGHT CHAIN 2, CYTOPLASMIC, MYOSIN VA VARIANT, ...
Authors:Bodor, A., Radnai, L., Hetenyi, C., Rapali, P., Lang, A., Kover, K.E., Perczel, A., Wahlgren, W.Y., Katona, G., Nyitray, L.
Deposit date:2014-04-24
Release date:2014-10-22
Last modified:2014-12-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dynll2 Dynein Light Chain Binds to an Extended Linear Motif of Myosin 5A Tail that Has Structural Plasticity.
Biochemistry, 53, 2014
5LPU
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CRYSTAL STRUCTURE OF ANNEXIN A2 COMPLEXED WITH S100A4
Descriptor:Annexin A2, Protein S100-A4, CALCIUM ION, ...
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
5LPX
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CRYSTAL STRUCTURE OF PKC PHOSPHORYLATION-MIMICKING MUTANT (S26E) ANNEXIN A2
Descriptor:Annexin A2, CALCIUM ION, GLYCEROL
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
5LQ0
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CRYSTAL STRUCTURE OF TYR24 PHOSPHORYLATED ANNEXIN A2 AT 2.9 A RESOLUTION
Descriptor:Annexin A2, CALCIUM ION
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
5LQ2
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CRYSTAL STRUCTURE OF TYR24 PHOSPHORYLATED ANNEXIN A2 AT 3.4 A RESOLUTION
Descriptor:Annexin A2, CALCIUM ION
Authors:Ecsedi, P., Gogl, G., Kiss, B., Nyitray, L.
Deposit date:2016-08-15
Release date:2017-07-05
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Regulation of the Equilibrium between Closed and Open Conformations of Annexin A2 by N-Terminal Phosphorylation and S100A4-Binding.
Structure, 25, 2017
5N7D
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MAGI-1 COMPLEXED WITH A RSK1 PEPTIDE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1,Annexin A2, Ribosomal protein S6 kinase alpha-1, ...
Authors:Gogl, G., Nyitray, L.
Deposit date:2017-02-20
Release date:2017-11-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dynamic control of RSK complexes by phosphoswitch-based regulation.
FEBS J., 285, 2018
5N7F
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MAGI-1 COMPLEXED WITH A PRSK1 PEPTIDE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1,Annexin A2, Ribosomal protein S6 kinase alpha-1, ...
Authors:Gogl, G., Nyitray, L.
Deposit date:2017-02-20
Release date:2017-11-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dynamic control of RSK complexes by phosphoswitch-based regulation.
FEBS J., 285, 2018
5N7G
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MAGI-1 COMPLEXED WITH A SYNTHETIC PRSK1 PEPTIDE
Descriptor:Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1,Annexin A2, Ribosomal protein S6 kinase alpha-1, ...
Authors:Gogl, G., Nyitray, L.
Deposit date:2017-02-20
Release date:2017-11-08
Last modified:2018-01-17
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Dynamic control of RSK complexes by phosphoswitch-based regulation.
FEBS J., 285, 2018
5CSF
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S100B-RSK1 CRYSTAL STRUCTURE A
Descriptor:Protein S100-B, Ribosomal protein S6 kinase alpha-1, CALCIUM ION
Authors:Gogl, G., Nyitray, L.
Deposit date:2015-07-23
Release date:2015-11-11
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.
J.Biol.Chem., 291, 2016
5CSI
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S100B-RSK1 CRYSTAL STRUCTURE A'
Descriptor:Protein S100-B, Ribosomal protein S6 kinase alpha-1, CALCIUM ION
Authors:Gogl, G., Nyitray, L.
Deposit date:2015-07-23
Release date:2015-11-11
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.
J.Biol.Chem., 291, 2016
5CSJ
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S100B-RSK1 CRYSTAL STRUCTURE B
Descriptor:Protein S100-B, Ribosomal protein S6 kinase alpha-1, CALCIUM ION, ...
Authors:Gogl, G., Nyitray, L.
Deposit date:2015-07-23
Release date:2015-11-11
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.
J.Biol.Chem., 291, 2016
5CSN
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S100B-RSK1 CRYSTAL STRUCTURE C
Descriptor:Protein S100-B, Ribosomal protein S6 kinase alpha-1, CALCIUM ION
Authors:Gogl, G., Nyitray, L.
Deposit date:2015-07-23
Release date:2015-11-11
Last modified:2016-01-13
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Structural Basis of Ribosomal S6 Kinase 1 (RSK1) Inhibition by S100B Protein: MODULATION OF THE EXTRACELLULAR SIGNAL-REGULATED KINASE (ERK) SIGNALING CASCADE IN A CALCIUM-DEPENDENT WAY.
J.Biol.Chem., 291, 2016
3BAS
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CRYSTAL STRUCTURE OF THE N-TERMINAL REGION OF THE SCALLOP MYOSIN ROD, MONOCLINIC (C2) FORM
Descriptor:Myosin heavy chain, striated muscle/General control protein GCN4 chimera, IODIDE ION
Authors:Brown, J.H., Cohen, C.
Deposit date:2007-11-08
Release date:2008-01-08
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins.
J.Mol.Biol., 375, 2008
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