Author results

1GUA
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HUMAN RAP1A, RESIDUES 1-167, DOUBLE MUTANT (E30D,K31E) COMPLEXED WITH GPPNHP AND THE RAS-BINDING-DOMAIN OF HUMAN C-RAF1, RESIDUES 51-131
Descriptor:RAP1A, C-RAF1, MAGNESIUM ION, ...
Authors:Nassar, N., Wittinghofer, A.
Deposit date:1996-06-18
Release date:1997-01-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Ras/Rap effector specificity determined by charge reversal.
Nat.Struct.Biol., 3, 1996
1C1Y
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CRYSTAL STRUCTURE OF RAP.GMPPNP IN COMPLEX WITH THE RAS-BINDING-DOMAIN OF C-RAF1 KINASE (RAFRBD).
Descriptor:RAS-RELATED PROTEIN RAP-1A, PROTO-ONCOGENE SERINE/THREONINE PROTEIN KINASE RAF-1, MAGNESIUM ION, ...
Authors:Nassar, N.
Deposit date:1999-07-22
Release date:1999-08-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue.
Nature, 375, 1995
1GRN
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CRYSTAL STRUCTURE OF THE CDC42/CDC42GAP/ALF3 COMPLEX.
Descriptor:PROTEIN (GTP BINDING PROTEIN), PROTEIN (RHO GTPASE ACTIVATING PROTEIN), MAGNESIUM ION, ...
Authors:Nassar, N., Hoffman, G.R., Clardy, J.C., Cerione, R.A.
Deposit date:1998-07-30
Release date:1999-12-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nat.Struct.Biol., 5, 1998
1XJ0
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CRYSTAL STRUCTURE OF THE GDP-BOUND FORM OF THE RASG60A MUTANT
Descriptor:Transforming protein p21/H-Ras-1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Nassar, N., Skowronek, K.
Deposit date:2004-09-22
Release date:2005-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of an intermediate for nucleotide exchange by Ras
To be Published
2NGR
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TRANSITION STATE COMPLEX FOR GTP HYDROLYSIS BY CDC42: COMPARISONS OF THE HIGH RESOLUTION STRUCTURES FOR CDC42 BOUND TO THE ACTIVE AND CATALYTICALLY COMPROMISED FORMS OF THE CDC42-GAP.
Descriptor:PROTEIN (GTP BINDING PROTEIN (G25K)), PROTEIN (GTPASE ACTIVATING PROTEIN (RHG)), MAGNESIUM ION, ...
Authors:Nassar, N., Hoffman, G., Clardy, J., Cerione, R.
Deposit date:1998-07-31
Release date:1999-01-06
Last modified:2018-03-14
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Nat.Struct.Biol., 5, 1998
3LO5
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CRYSTAL STRUCTURE OF THE DOMINANT NEGATIVE S17N MUTANT OF RAS
Descriptor:GTPase HRas, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
Authors:Nassar, N., Singh, K., Garcia-Diaz, M.
Deposit date:2010-02-03
Release date:2010-03-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.568 Å)
Cite:Structure of the Dominant Negative S17N Mutant of Ras
Biochemistry, 49, 2010
2H0Q
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CRYSTAL STRUCTURE OF THE PGM DOMAIN OF THE SUPPRESSOR OF T-CELL RECEPTOR (STS-1)
Descriptor:Suppressor of T-cell receptor signaling 1
Authors:Nassar, N., Ford, B., Carpino, N.
Deposit date:2006-05-15
Release date:2007-11-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:A phosphatase activity of Sts-1 contributes to the suppression of TCR signaling.
Mol.Cell, 27, 2007
3DB1
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CRYSTAL STRUCTURE OF THE 2H-PHOSPHATASE DOMAIN OF STS-2 IN COMPLEX WITH PHOSPHATE
Descriptor:STS-2 protein, PHOSPHATE ION
Authors:Nassar, N., Chen, Y., Carpino, N.
Deposit date:2008-05-30
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.
Biochemistry, 48, 2009
3MBK
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THE 1.35 A STRUCTURE OF THE PHOSPHATASE DOMAIN OF THE SUPPRESSOR OF T CELL RECEPTOR SIGNALLING PROTEIN IN COMPLEX WITH SULPHATE
Descriptor:Ubiquitin-associated and SH3 domain-containing protein B, SULFATE ION
Authors:Nassar, N., Jakoncic, J.
Deposit date:2010-03-25
Release date:2010-06-23
Last modified:2015-01-28
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The 1.35 A resolution structure of the phosphatase domain of the suppressor of T-cell receptor signaling protein in complex with sulfate.
Acta Crystallogr.,Sect.F, 66, 2010
1ZVQ
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STRUCTURE OF THE Q61G MUTANT OF RAS IN THE GDP-BOUND FORM
Descriptor:Transforming protein p21/H-Ras-1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Ford, B., Nassar, N.
Deposit date:2005-06-02
Release date:2006-03-14
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of a transient intermediate for GTP hydrolysis by ras.
Structure, 14, 2006
1ZW6
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CRYSTAL STRUCTURE OF THE GTP-BOUND FORM OF RASQ61G
Descriptor:Transforming protein p21/H-Ras-1, MAGNESIUM ION, CALCIUM ION, ...
Authors:Ford, B., Hornak, V., Kleinman, H., Nassar, N.
Deposit date:2005-06-03
Release date:2006-03-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structure of a transient intermediate for GTP hydrolysis by ras.
Structure, 14, 2006
3C7T
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CRYSTAL STRUCTURE OF THE ECDYSONE PHOSPHATE PHOSPHATASE, EPPASE, FROM BOMBIX MORI IN COMPLEX WITH TUNGSTATE
Descriptor:Ecdysteroid-phosphate phosphatase, TUNGSTATE(VI)ION, CHLORIDE ION, ...
Authors:Chen, Y., Carpino, N., Nassar, N.
Deposit date:2008-02-08
Release date:2009-03-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Structural and functional characterization of the c-terminal domain of the ecdysteroid phosphate phosphatase from Bombyx mori reveals a new enzymatic activity.
Biochemistry, 47, 2008
3D4I
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CRYSTAL STRUCTURE OF THE 2H-PHOSPHATASE DOMAIN OF STS-2
Descriptor:Sts-2 protein, CHLORIDE ION
Authors:Chen, Y., Carpino, N., Nassar, N.
Deposit date:2008-05-14
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.
Biochemistry, 48, 2009
3D6A
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CRYSTAL STRUCTURE OF THE 2H-PHOSPHATASE DOMAIN OF STS-2 IN COMPLEX WITH TUNGSTATE.
Descriptor:Sts-2 protein, MAGNESIUM ION, SODIUM ION, ...
Authors:Chen, Y., Carpino, N., Nassar, N.
Deposit date:2008-05-19
Release date:2009-03-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and functional characterization of the 2H-phosphatase domain of Sts-2 reveals an acid-dependent phosphatase activity.
Biochemistry, 48, 2009
2IKQ
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CRYSTAL STRUCTURE OF MOUSE STS-1 PGM DOMAIN IN COMPLEX WITH PHOSPHATE
Descriptor:Suppressor of T-cell receptor signaling 1, PHOSPHATE ION
Authors:Chen, Y., Nassar, N.
Deposit date:2006-10-02
Release date:2007-08-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.609 Å)
Cite:A Phosphatase Activity of Sts-1 Contributes to the Suppression of TCR Signaling
Mol.Cell, 27, 2007
1A12
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REGULATOR OF CHROMOSOME CONDENSATION (RCC1) OF HUMAN
Descriptor:REGULATOR OF CHROMOSOME CONDENSATION 1
Authors:Renault, L., Nassar, N., Vetter, I., Becker, J., Roth, M., Wittinghofer, A.
Deposit date:1997-12-19
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The 1.7 A crystal structure of the regulator of chromosome condensation (RCC1) reveals a seven-bladed propeller.
Nature, 392, 1998
1DOA
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STRUCTURE OF THE RHO FAMILY GTP-BINDING PROTEIN CDC42 IN COMPLEX WITH THE MULTIFUNCTIONAL REGULATOR RHOGDI
Descriptor:PROTEIN (GTP-BINDING PROTEIN), PROTEIN (GDP-DISSOCIATION INHIBITOR 1), MAGNESIUM ION, ...
Authors:Hoffman, G.R., Nassar, N., Cerione, R.C.
Deposit date:1999-12-20
Release date:2000-02-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI.
Cell(Cambridge,Mass.), 100, 2000
1LF0
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CRYSTAL STRUCTURE OF RASA59G IN THE GTP-BOUND FORM
Descriptor:Transforming protein P21/H-RAS-1, MAGNESIUM ION, CALCIUM ION, ...
Authors:Hall, B.E., Bar-Sagi, D., Nassar, N.
Deposit date:2002-04-10
Release date:2002-11-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for the Transition from Ras-GTP to Ras-GDP
Proc.Natl.Acad.Sci.USA, 99, 2002
1LF5
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CRYSTAL STRUCTURE OF RASA59G IN THE GDP-BOUND FORM
Descriptor:Transforming protein P21/H-RAS-1, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
Authors:Hall, B.E., Bar-Sagi, D., Nassar, N.
Deposit date:2002-04-10
Release date:2002-11-06
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The Structural Basis for the Transition from Ras-GTP to Ras-GDP
Proc.Natl.Acad.Sci.USA, 99, 2002
1NI2
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STRUCTURE OF THE ACTIVE FERM DOMAIN OF EZRIN
Descriptor:Ezrin
Authors:Smith, W.J., Nassar, N., Bretscher, A.P., Cerione, R.A., Karplus, P.A.
Deposit date:2002-12-20
Release date:2003-02-25
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the Active N-terminal Domain of Ezrin. CONFORMATIONAL AND MOBILITY CHANGES IDENTIFY KEYSTONE INTERACTIONS.
J.Biol.Chem., 278, 2003
1NTY
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CRYSTAL STRUCTURE OF THE FIRST DH/PH DOMAIN OF TRIO TO 1.7 A
Descriptor:Triple functional domain protein
Authors:Skowronek, K.R., Zheng, Y., Nassar, N.
Deposit date:2003-01-30
Release date:2004-06-29
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids.
J.Biol.Chem., 279, 2004
1XCM
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CRYSTAL STRUCTURE OF THE GPPNHP-BOUND H-RAS G60A MUTANT
Descriptor:Transforming protein p21/H-Ras-1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
Authors:Ford, B., Nassar, N.
Deposit date:2004-09-02
Release date:2005-05-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structure of the GppNHp-bound form of the RasG60A mutant
To be Published
2DFK
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CRYSTAL STRUCTURE OF THE CDC42-COLLYBISTIN II COMPLEX
Descriptor:collybistin II, cell division cycle 42 isoform 1, GLYCEROL, ...
Authors:Xiang, S., Kim, E.Y., Connelly, J.J., Nassar, N., Kirsch, J., Winking, J., Schwarz, G., Schindelin, H.
Deposit date:2006-03-02
Release date:2006-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal Structure of Cdc42 in Complex with Collybistin II, a Gephyrin-interacting Guanine Nucleotide Exchange Factor.
J.Mol.Biol., 359, 2006
1SER
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THE 2.9 ANGSTROMS CRYSTAL STRUCTURE OF T. THERMOPHILUS SERYL-TRNA SYNTHETASE COMPLEXED WITH TRNA SER
Descriptor:TRNASER, PROTEIN (SERYL-TRNA SYNTHETASE (E.C.6.1.1.11))
Authors:Biou, S., Cusack, V., Yaremchuk, A., Tukalo, M.
Deposit date:1994-02-21
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The 2.9 A crystal structure of T. thermophilus seryl-tRNA synthetase complexed with tRNA(Ser).
Science, 263, 1994
1SES
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CRYSTAL STRUCTURES AT 2.5 ANGSTROMS RESOLUTION OF SERYL-TRNA SYNTHETASE COMPLEXED WITH TWO DIFFERENT ANALOGUES OF SERYL-ADENYLATE
Descriptor:SERYL-tRNA SYNTHETASE, SERYL-HYDROXAMATE-ADENOSINE MONOPHOSPHATE, ADENOSINE MONOPHOSPHATE
Authors:Cusack, S., Belrhali, H.
Deposit date:1994-02-21
Release date:1994-07-31
Last modified:2012-02-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structures at 2.5 angstrom resolution of seryl-tRNA synthetase complexed with two analogs of seryl adenylate.
Science, 263, 1994
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