1WZB
| Crystal structure of the collagen triple helix model [{HYP(R)-HYP(R)-GLY}10]3 | Descriptor: | Collagen triple helix | Authors: | Kawahara, K, Nakamura, S, Nishi, Y, Uchiyama, S, Nishiuchi, Y, Nakazawa, T, Ohkubo, T, Kobayashi, Y. | Deposit date: | 2005-03-03 | Release date: | 2006-01-31 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Effect of hydration on the stability of the collagen-like triple-helical structure of [4(R)-hydroxyprolyl-4(R)-hydroxyprolylglycine]10 Biochemistry, 44, 2005
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3B2C
| Crystal structure of the collagen triple helix model [{PRO-HYP(R)-GLY}4-{HYP(S)-Pro-GLY}2-{PRO-HYP(R)-GLY}4]3 | Descriptor: | Collagen-like peptide | Authors: | Motooka, D, Kawahara, K, Nakamura, S, Doi, M, Nishi, Y, Nishiuchi, Y, Nakazawa, T, Yoshida, T, Ohkubo, T, Kobayashi, Y, Kang, Y.K, Uchiyama, S. | Deposit date: | 2011-07-26 | Release date: | 2012-04-04 | Method: | X-RAY DIFFRACTION (1.36 Å) | Cite: | The triple helical structure and stability of collagen model peptide with 4(S)-hydroxyprolyl-pro-gly units Biopolymers, 98, 2011
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6JQR
| Crystal structure of FLT3 in complex with gilteritinib | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, 6-ethyl-3-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide, GLYCEROL, ... | Authors: | Amano, Y. | Deposit date: | 2019-04-01 | Release date: | 2019-11-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells. Oncotarget, 10, 2019
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7DHL
| Crystal structure of FGFR3 in complex with pyrimidine derivative | Descriptor: | 5-[2-(3,5-dimethoxyphenyl)ethyl]-N-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]pyrimidin-2-amine, Fibroblast growth factor receptor 3 | Authors: | Echizen, Y, Tateishi, Y, Amano, Y. | Deposit date: | 2020-11-16 | Release date: | 2021-02-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency. Bioorg.Med.Chem., 33, 2021
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2E5B
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2E5D
| Crystal structure of Human NMPRTase complexed with nicotinamide | Descriptor: | NICOTINAMIDE, Nicotinamide phosphoribosyltransferase | Authors: | Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. | Deposit date: | 2006-12-20 | Release date: | 2007-12-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase J.Biochem., 147, 2010
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2E5C
| Crystal structure of Human NMPRTase complexed with 5'-phosphoribosyl-1'-pyrophosphate | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Nicotinamide phosphoribosyltransferase | Authors: | Takahashi, R, Nakamura, S, Kobayashi, Y, Ohkubo, T. | Deposit date: | 2006-12-20 | Release date: | 2007-12-25 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure and reaction mechanism of human nicotinamide phosphoribosyltransferase J.Biochem., 147, 2010
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