Author results

1IS1
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CRYSTAL STRUCTURE OF RIBOSOME RECYCLING FACTOR FROM VIBRIO PARAHAEMOLYTICUS
Descriptor:RIBOSOME RECYCLING FACTOR
Authors:Nakano, H., Yamaichi, Y., Uchiyama, S., Yoshida, T., Nishina, K., Kato, H., Ohkubo, T., Honda, T., Yamagata, Y., Kobayashi, Y.
Deposit date:2001-11-05
Release date:2003-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure and binding mode of a ribosome recycling factor (RRF) from mesophilic bacterium
J.BIOL.CHEM., 278, 2003
1ISE
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CRYSTAL STRUCTURE OF A MUTANT OF RIBOSOME RECYCLING FACTOR FROM ESCHERICHIA COLI, ARG132GLY
Descriptor:Ribosome Recycling Factor
Authors:Nakano, H., Yoshida, T., Oka, S., Uchiyama, S., Nishina, K., Ohkubo, T., Kato, H., Yamagata, Y., Kobayashi, Y.
Deposit date:2001-11-30
Release date:2003-10-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of a mutant of ribosome recycling factor from Escherichia coli, Arg132Gly
To be Published
3AHM
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PZ PEPTIDASE A
Descriptor:Oligopeptidase, ZINC ION, ACETATE ION
Authors:Nakano, H.
Deposit date:2010-04-25
Release date:2010-08-25
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:The exquisite structure and reaction mechanism of bacterial Pz-peptidase A toward collagenous peptides: X-ray crystallographic structure analysis of PZ-peptidase a reveals differences from mammalian thimet oligopeptidase.
J.Biol.Chem., 285, 2010
3AHN
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PZ PEPTIDASE A WITH INHIBITOR 1
Descriptor:Oligopeptidase, N~2~-{(2S)-3-[(R)-hydroxy{(1R)-2-phenyl-1-[(phenylacetyl)amino]ethyl}phosphoryl]-2-methylpropanoyl}-L-lysyl-D-serine, ZINC ION, ...
Authors:Nakano, H.
Deposit date:2010-04-25
Release date:2010-08-25
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The exquisite structure and reaction mechanism of bacterial Pz-peptidase A toward collagenous peptides: X-ray crystallographic structure analysis of PZ-peptidase a reveals differences from mammalian thimet oligopeptidase.
J.Biol.Chem., 285, 2010
3AHO
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PZ PEPTIDASE A WITH INHIBITOR 2
Descriptor:Oligopeptidase, ZINC ION, 1-{3-[(R)-{(1R)-1-[(glycyl-L-prolyl)amino]-2-phenylethyl}(hydroxy)phosphoryl]propanoyl}-L-prolyl-D-norleucine, ...
Authors:Nakano, H.
Deposit date:2010-04-25
Release date:2010-09-01
Last modified:2015-12-16
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:The exquisite structure and reaction mechanism of bacterial Pz-peptidase A toward collagenous peptides: X-ray crystallographic structure analysis of PZ-peptidase a reveals differences from mammalian thimet oligopeptidase.
J.Biol.Chem., 285, 2010
2EK8
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AMINOPEPTIDASE FROM ANEURINIBACILLUS SP. STRAIN AM-1
Descriptor:Aminopeptidase, ZINC ION, ISOPROPYL ALCOHOL
Authors:Akioka, M., Nakano, H., Watanabe, K.
Deposit date:2007-03-22
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural characterization of a novel bacterial aminopeptidase with an apical domain from aneurinibacillus sp. strain AM-1
To be published
2EK9
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AMINOPEPTIDASE FROM ANEURINIBACILLUS SP. STRAIN AM-1 WITH BESTATIN
Descriptor:Aminopeptidase, ZINC ION, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, ...
Authors:Akioka, M., Nakano, H., Watanabe, K.
Deposit date:2007-03-22
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structural characterization of a novel bacterial aminopeptidase with an apical domain from aneurinibacillus sp. strain AM-1
To be published
1GE9
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SOLUTION STRUCTURE OF THE RIBOSOME RECYCLING FACTOR
Descriptor:RIBOSOME RECYCLING FACTOR
Authors:Yoshida, T., Uchiyama, S., Nakano, H., Kashimori, H., Kijima, H., Ohshima, T., Saihara, Y., Ishino, T., Shimahara, T., Yoshida, T., Yokose, K., Ohkubo, T., Kaji, A., Kobayashi, Y.
Deposit date:2000-10-19
Release date:2001-05-16
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the ribosome recycling factor from Aquifex aeolicus.
Biochemistry, 40, 2001
2D1X
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THE CRYSTAL STRUCTURE OF THE CORTACTIN-SH3 DOMAIN AND AMAP1-PEPTIDE COMPLEX
Descriptor:cortactin isoform a, proline rich region from development and differentiation enhancing factor 1, SULFATE ION
Authors:Hashimoto, S., Hirose, M., Hashimoto, A., Morishige, M., Yamada, A., Hosaka, H., Akagi, K., Ogawa, E., Oneyama, C., Agatsuma, T., Okada, M., Kobayashi, H., Wada, H., Nakano, H., Ikegami, T., Nakagawa, A., Sabe, H.
Deposit date:2005-09-01
Release date:2006-04-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2ZZO
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN GP41 FRAGMENT N36 AND FUSION INHIBITOR C34/S138A
Descriptor:Transmembrane protein
Authors:Watabe, T., Nakano, H., Nakatsu, T., Kato, H., Fujii, N.
Deposit date:2009-02-20
Release date:2009-08-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:X-ray crystallographic study of an HIV-1 fusion inhibitor with the gp41 S138A substitution
J.Mol.Biol., 392, 2009
3WD0
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SERRATIA MARCESCENS CHITINASE B, TETRAGONAL FORM
Descriptor:Chitinase B, GLYCEROL, SULFATE ION, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
3WD1
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH SYN-TRIAZOLE INHIBITOR
Descriptor:Chitinase B, GLYCEROL, SULFATE ION, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
3WD2
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH AZIDE INHIBITOR
Descriptor:Chitinase B, [2-[[(2S)-1-[bis(phenylmethyl)amino]-5-[[N-(methylcarbamoyl)carbamimidoyl]amino]-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-diazonio-azanide, GLYCEROL, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
3WD3
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH AZIDE INHIBITOR
Descriptor:Chitinase B, [2-[[(2S)-1-[bis(phenylmethyl)amino]-5-[[N-(methylcarbamoyl)carbamimidoyl]amino]-1-oxidanylidene-pentan-2-yl]amino]-2-oxidanylidene-ethyl]-diazonio-azanide, GLYCEROL, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
3WD4
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH AZIDE INHIBITOR AND QUINOLINE COMPOUND
Descriptor:Chitinase B, GLYCEROL, SULFATE ION, ...
Authors:Hirose, T., Maita, N., Gouda, H., Koseki, J., Yamamoto, T., Sugawara, A., Nakano, H., Hirono, S., Shiomi, K., Watanabe, T., Taniguchi, H., Sharpless, K.B., Omura, S., Sunazuka, T.
Deposit date:2013-06-06
Release date:2013-09-18
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
Proc.Natl.Acad.Sci.USA, 110, 2013
2DT4
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CRYSTAL STRUCTURE OF PYROCOCCUS HORIKOSHII A PLANT- AND PROKARYOTE-CONSERVED (PPC) PROTEIN AT 1.60 RESOLUTION
Descriptor:Hypothetical protein PH0802, GLYCEROL
Authors:Lin, L., Nakano, H., Uchiyama, S., Fujimoto, S., Matsunaga, S., Nakamura, S.
Deposit date:2006-07-10
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structure of Pyrococcus horikoshii PPC protein at 1.60 A resolution
Proteins, 67, 2007
3AHA
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CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN GP41 FRAGMENTS N36 AND C34 MUTANT N126K/E137Q
Descriptor:Transmembrane protein gp41, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION
Authors:Izumi, K., Nakamura, S., Nakano, H., Shimura, K., Sakagami, Y., Oishi, S., Uchiyama, S., Ohkubo, T., Kobayashi, Y., Fujii, N., Matsuoka, M., Kodama, E.N.
Deposit date:2010-04-22
Release date:2010-05-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino terminal heptad repeat.
Antiviral Res., 2010
5IB9
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CRYSTAL STRUCTURE OF AMINOPEPTIDASE EQUIPPED WITH PAD FROM ANEURINIBACILLUS SP. AM-1
Descriptor:Aminopeptidase, ZINC ION, 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID
Authors:Tagawa, R., Nakano, H., Watanabe, K.
Deposit date:2016-02-22
Release date:2017-02-22
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of aminopeptidase
To Be Published
3UMW
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CRYSTAL STRUCTURE OF PIM1 KINASE IN COMPLEX WITH INHIBITOR (Z)-2-[(1H-INDAZOL-3-YL)METHYLENE]-6-METHOXY-7-(PIPERAZIN-1-YLMETHYL)BENZOFURAN-3(2H)-ONE
Descriptor:Proto-oncogene serine/threonine-protein kinase pim-1, GLYCEROL, SULFATE ION, ...
Authors:Parker, L.J., Handa, N., Yokoyama, S.
Deposit date:2011-11-14
Release date:2012-10-03
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Rational evolution of a novel type of potent and selective proviral integration site in Moloney murine leukemia virus kinase 1 (PIM1) inhibitor from a screening-hit compound.
J.Med.Chem., 55, 2012
4Z2G
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH MACROLIDE INHIBITOR 26
Descriptor:Chitinase B, (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {4-[N'-(methylcarbamoyl)carbamimidamido]butyl}carbamate
Authors:Maita, N., Sugawara, A., Sunazuka, T.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
4Z2H
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH MACROLIDE INHIBITOR 29
Descriptor:Chitinase B, (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {2-[N'-(methylcarbamoyl)carbamimidamido]ethyl}carbamate, GLYCEROL, ...
Authors:Maita, N., Sugawara, A., Sunazuka, T.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
4Z2I
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH MACROLIDE INHIBITOR 30
Descriptor:Chitinase B, (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {3-[N'-(methylcarbamoyl)carbamimidamido]propyl}carbamate, SODIUM ION, ...
Authors:Maita, N., Sugawara, A., Sunazuka, T.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2 Å)
Cite:Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
4Z2J
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH MACROLIDE INHIBITOR 31
Descriptor:Chitinase B, (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {5-[N'-(methylcarbamoyl)carbamimidamido]pentyl}carbamate, GLYCEROL, ...
Authors:Maita, N., Sugawara, A., Sunazuka, T.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
4Z2K
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH MACROLIDE INHIBITOR 32
Descriptor:Chitinase B, (1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,17S)-3-ethyl-2,10-dihydroxy-2,6,8,10,12,15,15,17-octamethyl-5-oxo-9-(prop-2-yn-1-yloxy)-4,14,16-trioxabicyclo[11.3.1]heptadec-7-yl {7-[N'-(methylcarbamoyl)carbamimidamido]heptyl}carbamate, GLYCEROL
Authors:Maita, N., Sugawara, A., Sunazuka, T.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
4Z2L
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SERRATIA MARCESCENS CHITINASE B COMPLEXED WITH MACROLIDE INHIBITOR 33
Descriptor:Chitinase B, (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-14-ethyl-7,10,12,13-tetrahydroxy-3,5,7,9,11,13-hexamethyl-2-oxo-6-(prop-2-yn-1-yloxy)oxacyclotetradecan-4-yl {3-[N'-(methylcarbamoyl)carbamimidamido]propyl}carbamate, GLYCEROL, ...
Authors:Maita, N., Sugawara, A., Sunazuka, T.
Deposit date:2015-03-30
Release date:2015-07-01
Last modified:2015-07-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Creation of Customized Bioactivity within a 14-Membered Macrolide Scaffold: Design, Synthesis, and Biological Evaluation Using a Family-18 Chitinase
J.Med.Chem., 58, 2015
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