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1M5X
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CRYSTAL STRUCTURE OF THE HOMING ENDONUCLEASE I-MSOI BOUND TO ITS DNA SUBSTRATE
Descriptor:5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', DNA endonuclease I-MsoI, ...
Authors:Chevalier, B., Turmel, M., Lemieux, C., Monnat, R.J., Stoddard, B.L.
Deposit date:2002-07-10
Release date:2003-06-03
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI
J.Mol.Biol., 329, 2003
1N3E
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CRYSTAL STRUCTURE OF I-CREI BOUND TO A PALINDROMIC DNA SEQUENCE I (PALINDROME OF LEFT SIDE OF WILDTYPE DNA TARGET SEQUENCE)
Descriptor:5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3', 5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*CP*G)-3', DNA endonuclease I-CreI, ...
Authors:Chevalier, B., Turmel, M., Lemieux, C., Monnat, R.J., Stoddard, B.L.
Deposit date:2002-10-28
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI
J.Mol.Biol., 329, 2003
1N3F
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CRYSTAL STRUCTURE OF I-CREI BOUND TO A PALINDROMIC DNA SEQUENCE II (PALINDROME OF RIGHT SIDE OF WILDTYPE DNA TARGET SEQUENCE)
Descriptor:5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*GP*A)-3', 5'-D(P*GP*AP*CP*AP*GP*TP*TP*TP*CP*G-3'), DNA endonuclease I-CreI, ...
Authors:Chevalier, B., Turmel, M., Lemieux, C., Monnat, R.J., Stoddard, B.L.
Deposit date:2002-10-28
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Flexible DNA Target Site Recognition by Divergent Homing Endonuclease Isoschizomers I-CreI and I-MsoI
J.Mol.Biol., 329, 2003
2FLD
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I-MSOI RE-DESIGNED FOR ALTERED DNA CLEAVAGE SPECIFICITY
Descriptor:5'-D(*GP*CP*AP*GP*AP*AP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*TP*TP*CP*TP*GP*C)-3', DNA ENDONUCLEASE I-MSOI, ...
Authors:Ashworth, J., Duarte, C.M., Havranek, J.J., Sussman, D., Monnat, R.J., Stoddard, B.L., Baker, D.
Deposit date:2006-01-05
Release date:2006-06-06
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Computational redesign of endonuclease DNA binding and cleavage specificity.
Nature, 441, 2006
3FD2
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CRYSTAL STRUCTURE OF MMSOI/DNA COMPLEX WITH CALCIUM
Descriptor:Site-specific DNA endonuclease I-MsoI, 5'-D(*GP*CP*AP*GP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*CP*CP*G)-3', 5'-D(*CP*GP*GP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*CP*TP*GP*C)-3', ...
Authors:Li, H., Monnat, R.J.
Deposit date:2008-11-24
Release date:2009-06-30
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins.
Nucleic Acids Res., 37, 2009
1G9Y
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HOMING ENDONUCLEASE I-CREI / DNA SUBSTRATE COMPLEX WITH CALCIUM
Descriptor:5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*TP*TP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', DNA ENDONUCLEASE I-CREI, ...
Authors:Chevalier, B., Monnat, R.J., Stoddard, B.L.
Deposit date:2000-11-28
Release date:2001-04-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites.
Nat.Struct.Biol., 8, 2001
1G9Z
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LAGLIDADG HOMING ENDONUCLEASE I-CREI / DNA PRODUCT COMPLEX WITH MAGNESIUM
Descriptor:5'-D(*GP*CP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*GP*A)-3', 5'-D(P*GP*AP*CP*AP*GP*TP*TP*TP*CP*G)-3', 5'-D(*CP*GP*AP*AP*AP*CP*TP*GP*TP*CP*TP*CP*AP*C)-3', ...
Authors:Chevalier, B., Monnat, R.J., Stoddard, B.L.
Deposit date:2000-11-28
Release date:2001-04-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites.
Nat.Struct.Biol., 8, 2001
3FC3
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CRYSTAL STRUCTURE OF THE BETA-BETA-ALPHA-ME TYPE II RESTRICTION ENDONUCLEASE HPY99I
Descriptor:Restriction endonuclease Hpy99I, 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', ...
Authors:Sokolowska, M., Czapinska, H., Bochtler, M.
Deposit date:2008-11-21
Release date:2009-03-31
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA.
Nucleic Acids Res., 37, 2009
3GOX
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CRYSTAL STRUCTURE OF THE BETA-BETA-ALPHA-ME TYPE II RESTRICTION ENDONUCLEASE HPY99I IN THE ABSENCE OF EDTA
Descriptor:Restriction endonuclease Hpy99I, 5'-(*DCP*DTP*DCP*DGP*DAP*DCP*DGP*DTP*DAP*DGP*DA)-3', 5'-(*DTP*DAP*DCP*DGP*DTP*DCP*DGP*DAP*DGP*DTP*DC)-3', ...
Authors:Sokolowska, M., Czapinska, H., Bochtler, M.
Deposit date:2009-03-20
Release date:2009-04-28
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Crystal structure of the beta beta alpha-Me type II restriction endonuclease Hpy99I with target DNA.
Nucleic Acids Res., 37, 2009