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2ANO
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BU of 2ano by Molmil
Crystal structure of E.coli dihydrofolate reductase in complex with NADPH and the inhibitor MS-SH08-17
Descriptor: 1-{[N-(1-IMINO-GUANIDINO-METHYL)]SULFANYLMETHYL}-3-TRIFLUOROMETHYL-BENZENE, Dihydrofolate reductase, MANGANESE (II) ION, ...
Authors:Summerfield, R.L, Daigle, D.M, Mayer, S, Jackson, S.G, Organ, M, Hughes, D.W, Brown, E.D, Junop, M.S.
Deposit date:2005-08-11
Release date:2006-07-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.68 Å)
Cite:A 2.13 A Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region
J.Med.Chem., 49, 2006
2ANQ
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BU of 2anq by Molmil
Crystal Structure of E.coli DHFR in complex with NADPH and the inhibitor compound 10a.
Descriptor: (2,5-dimethylbenzene-1,4-diyl)dimethanediyl bis(N-carbamimidoylcarbamimidothioate), Dihydrofolate reductase, MANGANESE (II) ION, ...
Authors:Summerfield, R.L, Daigle, D.M, Mayer, S, Jackson, S.G, Organ, M, Hughes, D.W, Brown, E.D, Junop, M.S.
Deposit date:2005-08-11
Release date:2006-07-25
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.13 Å)
Cite:A 2.13 A Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region
J.Med.Chem., 49, 2006
1R2B
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BU of 1r2b by Molmil
Crystal structure of the BCL6 BTB domain complexed with a SMRT co-repressor peptide
Descriptor: B-cell lymphoma 6 protein, Nuclear receptor co-repressor 2
Authors:Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G.
Deposit date:2003-09-26
Release date:2003-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Mol.Cell, 12, 2003
1R28
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BU of 1r28 by Molmil
Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB domain to 2.2 Angstrom
Descriptor: B-cell lymphoma 6 protein
Authors:Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G.
Deposit date:2003-09-26
Release date:2003-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Mol.Cell, 12, 2003
1R29
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BU of 1r29 by Molmil
Crystal Structure of the B-Cell Lymphoma 6 (BCL6) BTB Domain to 1.3 Angstrom
Descriptor: B-cell lymphoma 6 protein
Authors:Ahmad, K.F, Melnick, A, Lax, S.A, Bouchard, D, Liu, J, Kiang, C.L, Mayer, S, Licht, J.D, Prive, G.G.
Deposit date:2003-09-26
Release date:2003-12-23
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain.
Mol.Cell, 12, 2003
1HL2
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BU of 1hl2 by Molmil
Crystal structure of N-acetylneuraminate lyase from E. coli mutant L142R in complex with b-hydroxypyruvate
Descriptor: 3-HYDROXYPYRUVIC ACID, N-ACETYLNEURAMINATE LYASE SUBUNIT
Authors:Joerger, A.C, Fersht, A.R.
Deposit date:2003-03-12
Release date:2003-05-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mimicking Natural Evolution in Vitro: An N-Acetylneuraminate Lyase Mutant with an Increased Dihydrodipicolinate Synthase Activity
Proc.Natl.Acad.Sci.USA, 100, 2003

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