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2Z9S
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CRYSTAL STRUCTURE ANALYSIS OF RAT HBP23/PEROXIREDOXIN I, CYS52SER MUTANT
Descriptor:Peroxiredoxin-1
Authors:Matsumura, T., Okamoto, K., Nishino, T., Abe, Y.
Deposit date:2007-09-25
Release date:2007-11-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Dimer-Oligomer Interconversion of Wild-type and Mutant Rat 2-Cys Peroxiredoxin: DISULFIDE FORMATION AT DIMER-DIMER INTERFACES IS NOT ESSENTIAL FOR DECAMERIZATION
J.Biol.Chem., 283, 2008
1WYG
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CRYSTAL STRUCTURE OF A RAT XANTHINE DEHYDROGENASE TRIPLE MUTANT (C535A, C992R AND C1324S)
Descriptor:Xanthine dehydrogenase/oxidase, PHOSPHATE ION, CALCIUM ION, ...
Authors:Nishino, T., Okamoto, K., Kawaguchi, Y., Hori, H., Matsumura, T., Eger, B.T., Pai, E.F., Nishino, T.
Deposit date:2005-02-14
Release date:2005-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Mechanism of the Conversion of Xanthine Dehydrogenase to Xanthine Oxidase: IDENTIFICATION OF THE TWO CYSTEINE DISULFIDE BONDS AND CRYSTAL STRUCTURE OF A NON-CONVERTIBLE RAT LIVER XANTHINE DEHYDROGENASE MUTANT
J.Biol.Chem., 280, 2005
2E3T
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CRYSTAL STRUCTURE OF RAT XANTHINE OXIDOREDUCTASE MUTANT (W335A AND F336L)
Descriptor:Xanthine dehydrogenase/oxidase, BICARBONATE ION, PHOSPHATE ION, ...
Authors:Asai, R., Nishino, T., Matsumura, T., Okamoto, K., Pai, E.F., Nishino, T.
Deposit date:2006-11-28
Release date:2007-09-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Two mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidase
J.Biochem.(Tokyo), 141, 2007
4YTZ
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RAT XANTHINE OXIDOREDUCTASE, C-TERMINAL DELETION PROTEIN VARIANT, CRYSTAL GROWN WITHOUT DITHIOTHREITOL
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Nishino, T., Okamoto, K., Kawaguchi, Y., Matsumura, T., Eger, B.T., Pai, E.F., Nishino, T.
Deposit date:2015-03-18
Release date:2015-04-22
Last modified:2015-09-02
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase
Febs J., 282, 2015
2E1Q
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CRYSTAL STRUCTURE OF HUMAN XANTHINE OXIDOREDUCTASE MUTANT, GLU803VAL
Descriptor:Xanthine dehydrogenase/oxidase, BICARBONATE ION, CALCIUM ION, ...
Authors:Yamaguchi, Y., Matsumura, T., Ichida, K., Okamoto, K., Nishino, T.
Deposit date:2006-10-27
Release date:2007-09-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate
J.Biochem.(Tokyo), 141, 2007
4YSW
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STRUCTURE OF RAT XANTHINE OXIDOREDUCTASE, C-TERMINAL DELETION PROTEIN VARIANT, NADH BOUND FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, CALCIUM ION, ...
Authors:Nishino, T., Okamoto, K., Kawaguchi, Y., Matsumura, T., Eger, B.T., Pai, E.F.
Deposit date:2015-03-17
Release date:2015-04-22
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase.
Febs J., 282, 2015
4YTY
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STRUCTURE OF RAT XANTHINE OXIDOREDUCTASE, C535A/C992R/C1324S, NADH BOUND FORM
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, CALCIUM ION, ...
Authors:Nishino, T., Okamoto, K., Kawaguchi, Y., Matsumura, T., Eger, B.T., Pai, E.F.
Deposit date:2015-03-18
Release date:2015-04-22
Last modified:2015-09-09
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase.
Febs J., 282, 2015
2P6V
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STRUCTURE OF TAFH DOMAIN OF THE HUMAN TAF4 SUBUNIT OF TFIID
Descriptor:Transcription initiation factor TFIID subunit 4, SULFATE ION
Authors:Wang, X., Truckses, D.M., Takada, S., Matsumura, T., Tanese, N., Jacobson, R.H.
Deposit date:2007-03-19
Release date:2007-05-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conserved region I of human coactivator TAF4 binds to a short hydrophobic motif present in transcriptional regulators.
Proc.Natl.Acad.Sci.Usa, 104, 2007
3WIN
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CLOSTRIDIUM BOTULINUM HEMAGGLUTININ
Descriptor:HA3, 17 kD hemagglutinin component, HA1
Authors:Amatsu, S., Sugawara, Y., Matsumura, T., Fujinaga, Y., Kitadokoro, K.
Deposit date:2013-09-19
Release date:2013-11-06
Last modified:2013-12-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Crystal Structure of Clostridium botulinum Whole Hemagglutinin Reveals a Huge Triskelion-shaped Molecular Complex
J.Biol.Chem., 288, 2013
3AM9
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COMPLEX OF BOVINE XANTHINE DEHYDROGENASE AND TRIHYDROXY FYX-051
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, CALCIUM ION, ...
Authors:Matsumoto, K., Okamoto, K., Ashizawa, N., Matsumura, T., Kusano, T., Nishino, T.
Deposit date:2010-08-18
Release date:2010-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:FYX-051: A Novel and Potent Hybrid-Type Inhibitor of Xanthine Oxidoreductase
J.Pharmacol.Exp.Ther., 336, 2011
4YRW
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RAT XANTHINE OXIDOREDUCTASE, C-TERMINAL DELETION PROTEIN VARIANT
Descriptor:Xanthine dehydrogenase/oxidase, FE2/S2 (INORGANIC) CLUSTER, BICARBONATE ION, ...
Authors:Okamoto, K.
Deposit date:2015-03-16
Release date:2015-04-29
Last modified:2015-09-16
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase
Febs J., 282, 2015
6K9U
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DISCOVERY OF PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVE AS A HIGHLY SELECTIVE PDE10A INHIBITOR
Descriptor:cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A, ZINC ION, MAGNESIUM ION, ...
Authors:Takedomi, K., Koizumi, Y.
Deposit date:2019-06-18
Release date:2019-07-17
Last modified:2019-08-07
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Discovery of a pyrazolo[1,5-a]pyrimidine derivative (MT-3014) as a highly selective PDE10A inhibitor via core structure transformation from the stilbene moiety.
Bioorg.Med.Chem., 27, 2019