5WSO | |
2GSG | | CRYSTAL STRUCTURE OF THE FV FRAGMENT OF A MONOCLONAL ANTIBODY SPECIFIC FOR POLY-GLUTAMINE | | Descriptor: | monoclonal antibody light chain, monoclonal antibody heavy chain, SULFATE ION | | Authors: | Li, P., Huey-Tubman, K.E., West Jr., A.P., Bennett, M.J., Bjorkman, P.J. | | Deposit date: | 2006-04-26 | | Release date: | 2007-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The structure of a polyQ-anti-polyQ complex reveals binding according to a linear lattice model.
Nat.Struct.Mol.Biol., 14, 2007
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3GA3 | | CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF HUMAN MDA5 | | Descriptor: | Interferon-induced helicase C domain-containing protein 1, MDA5, ZINC ION | | Authors: | Li, P. | | Deposit date: | 2009-02-16 | | Release date: | 2009-02-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Crystal structure of the C-terminal domain of human MDA5
To be Published
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1HYR | |
1B3J | | STRUCTURE OF THE MHC CLASS I HOMOLOG MIC-A, A GAMMADELTA T CELL LIGAND | | Descriptor: | MHC CLASS I HOMOLOG MIC-A, N-ACETYL-D-GLUCOSAMINE | | Authors: | Li, P., Willie, S., Bauer, S., Morris, D., Spies, T., Strong, R. | | Deposit date: | 1998-12-11 | | Release date: | 1999-07-09 | | Last modified: | 2011-11-16 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Crystal structure of the MHC class I homolog MIC-A, a gammadelta T cell ligand.
Immunity, 10, 1999
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1JFM | |
1N1A | | CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN FKBP52 | | Descriptor: | FKBP52 | | Authors: | Li, P., Ding, Y., Wu, B., Shu, C., Shen, B., Rao, Z. | | Deposit date: | 2002-10-16 | | Release date: | 2002-12-30 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structure of the N-terminal domain of human FKBP52.
Acta Crystallogr.,Sect.D, 59, 2003
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2OTU | | CRYSTAL STRUCTURE OF FV POLYGLUTAMINE COMPLEX | | Descriptor: | Fv light chain variable domain, Fv heavy chain variable domain, peptide antigen | | Authors: | Li, P. | | Deposit date: | 2007-02-09 | | Release date: | 2007-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.68 Å) | | Cite: | Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy
To be Published
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2OTW | | CRYSTAL STRUCTURE OF FV POLYGLUTAMINE COMPLEX | | Descriptor: | Fv light chain avriable domain VL, Fv heavy chain variable domain VH, poly-Gln peptide antigen | | Authors: | Li, P. | | Deposit date: | 2007-02-09 | | Release date: | 2007-04-24 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Implications of the structure of a poly-Gln/anti-poly-Gln complex for disease progression and therapy
To be Published
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4PP8 | |
1J4H | | CRYSTAL STRUCTURE ANALYSIS OF THE FKBP12 COMPLEXED WITH 000107 SMALL MOLECULE | | Descriptor: | FKBP12, 3-PHENYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PROPIONIC ACID ETHYL ESTER | | Authors: | Li, P., Ding, Y., Wang, L., Wu, B., Shu, C., Li, S., Shen, B., Rao, Z. | | Deposit date: | 2001-09-30 | | Release date: | 2003-06-03 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
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1J4I | | CRYSTAL STRUCTURE ANALYSIS OF THE FKBP12 COMPLEXED WITH 000308 SMALL MOLECULE | | Descriptor: | FKBP12, 4-METHYL-2-{[4-(TOLUENE-4-SULFONYL)-THIOMORPHOLINE-3-CARBONYL]-AMINO}-PENTANOIC ACID | | Authors: | Li, P., Ding, Y., Wang, L., Wu, B., Shu, C., Li, S., Shen, B., Rao, Z. | | Deposit date: | 2001-09-30 | | Release date: | 2003-06-03 | | Last modified: | 2019-10-23 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Design and structure-based study of new potential FKBP12 inhibitors.
Biophys.J., 85, 2003
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3EQT | |
5JLY | | STRUCTURE OF PEROXIREDOXIN-1 FROM SCHISTOSOMA JAPONICUM | | Descriptor: | Thioredoxin peroxidase-1 | | Authors: | Wu, Q., Huang, F., Zeng, D., Liu, X., Zhao, J., Wang, H., Peng, Y., Li, P., Li, Y. | | Deposit date: | 2016-04-27 | | Release date: | 2017-05-03 | | Method: | X-RAY DIFFRACTION (3.051 Å) | | Cite: | Crystal structure of Peroxiredoxin-1 from Schistosoma japonicum
To Be Published
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4LEV | | STRUCTURE OF HUMAN CGAS | | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | | Authors: | Li, P. | | Deposit date: | 2013-06-26 | | Release date: | 2013-12-25 | | Last modified: | 2014-01-08 | | Method: | X-RAY DIFFRACTION (1.952 Å) | | Cite: | Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
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4LEW | | STRUCTURE OF HUMAN CGAS | | Descriptor: | Cyclic GMP-AMP synthase, ZINC ION | | Authors: | Li, P. | | Deposit date: | 2013-06-26 | | Release date: | 2013-12-25 | | Last modified: | 2014-01-08 | | Method: | X-RAY DIFFRACTION (2.04 Å) | | Cite: | Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
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4LEY | | STRUCTURE OF MOUSE CGAS BOUND TO 18 BP DNA | | Descriptor: | Cyclic GMP-AMP synthase, 18 bp dsDNA, ZINC ION | | Authors: | Li, P. | | Deposit date: | 2013-06-26 | | Release date: | 2013-12-25 | | Last modified: | 2014-01-08 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
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4LEZ | | STRUCTURE OF MOUSE CGAS BOUND TO AN 18BP DNA AND CGAS PRODUCT | | Descriptor: | Cyclic GMP-AMP synthase, 18bp dsDNA, ZINC ION, ... | | Authors: | Li, P. | | Deposit date: | 2013-06-26 | | Release date: | 2013-12-25 | | Last modified: | 2015-08-05 | | Method: | X-RAY DIFFRACTION (2.36 Å) | | Cite: | Cyclic GMP-AMP Synthase Is Activated by Double-Stranded DNA-Induced Oligomerization.
Immunity, 39, 2013
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6AEM | | CRYSTAL STRUCTURE OF THE PKD1 DOMAIN OF VIBRIO ANGUILLARUM EPP | | Descriptor: | PKD domain, CALCIUM ION, ZINC ION | | Authors: | Ma, Q., Li, P. | | Deposit date: | 2018-08-05 | | Release date: | 2018-12-12 | | Method: | X-RAY DIFFRACTION (1.272 Å) | | Cite: | Structural basis for specific calcium binding by the polycystic-kidney-disease domain of Vibrio anguillarum protease Epp
Biochem. Biophys. Res. Commun., 505, 2018
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6O8B | | CRYSTAL STRUCTURE OF STING CTD IN COMPLEX WITH TBK1 | | Descriptor: | Stimulator of interferon genes protein, Serine/threonine-protein kinase TBK1, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | | Authors: | Li, P., Zhao, B., Du, F. | | Deposit date: | 2019-03-09 | | Release date: | 2019-05-22 | | Last modified: | 2019-06-12 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
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6O8C | | CRYSTAL STRUCTURE OF STING CTT IN COMPLEX WITH TBK1 | | Descriptor: | Serine/threonine-protein kinase TBK1, Stimulator of interferon genes protein, N-(3-{[5-iodo-4-({3-[(thiophen-2-ylcarbonyl)amino]propyl}amino)pyrimidin-2-yl]amino}phenyl)pyrrolidine-1-carboxamide | | Authors: | Li, P., Zhao, B., Du, F. | | Deposit date: | 2019-03-09 | | Release date: | 2019-05-22 | | Last modified: | 2019-06-12 | | Method: | X-RAY DIFFRACTION (3.17 Å) | | Cite: | A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature, 569, 2019
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3E3H | | CRYSTAL STRUCTURE OF THE OP HYDROLASE MUTANT FROM BREVUNDIMONAS DIMINUTA | | Descriptor: | Parathion hydrolase, COBALT (II) ION, DIETHYL 4-METHYLBENZYLPHOSPHONATE | | Authors: | Li, P., Reeves, T.E., Grimsley, J.K., Wild, J.R. | | Deposit date: | 2008-08-07 | | Release date: | 2008-10-07 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Balancing the stability and the catalytic specificities of OP hydrolases with enhanced V-agent activities.
Protein Eng.Des.Sel., 21, 2008
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3LRN | | CRYSTAL STRUCTURE OF HUMAN RIG-I CTD BOUND TO A 14 BP GC 5' PPP DSRNA | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(GTP)P*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION | | Authors: | Li, P. | | Deposit date: | 2010-02-11 | | Release date: | 2010-06-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
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3LRR | | CRYSTAL STRUCTURE OF HUMAN RIG-I CTD BOUND TO A 12 BP AU RICH 5' PPP DSRNA | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*(ATP)P*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*U)-3'), ZINC ION | | Authors: | Li, P. | | Deposit date: | 2010-02-11 | | Release date: | 2010-06-02 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The Structural Basis of 5' Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain.
Structure, 18, 2010
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3OG8 | | CRYSTAL STRUCTURE OF HUMAN RIG-I CTD BOUND TO A 14-BP BLUNT-ENDED DSRNA | | Descriptor: | ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*GP*CP*C)-3'), ZINC ION | | Authors: | Li, P. | | Deposit date: | 2010-08-16 | | Release date: | 2010-11-03 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of RIG-I C-terminal domain bound to blunt-ended double-strand RNA without 5' triphosphate.
Nucleic Acids Res., 39, 2011
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