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1H52
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BINDING OF PHOSPHATE AND PYROPHOSPHATE IONS AT THE ACTIVE SITE OF HUMAN ANGIOGENIN AS REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor:ANGIOGENIN, PYROPHOSPHATE 2-
Authors:Leonidas, D.D., Chavali, G.B., Jardine, A.M., Li, S., Shapiro, R., Acharya, K.R.
Deposit date:2001-05-18
Release date:2001-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography
Protein Sci., 10, 2001
1H53
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BINDING OF PHOSPHATE AND PYROPHOSPHATE IONS AT THE ACTIVE SITE OF HUMAN ANGIOGENIN AS REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor:ANGIOGENIN, CITRIC ACID, PHOSPHATE ION
Authors:Leonidas, D.D., Chavali, G.B., Jardine, A.M., Li, S., Shapiro, R., Acharya, K.R.
Deposit date:2001-05-18
Release date:2001-08-09
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography
Protein Sci., 10, 2001
1HBY
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BINDING OF PHOSPHATE AND PYROPHOSPHATE IONS AT THE ACTIVE SITE OF HUMAN ANGIOGENIN AS REVEALED BY X-RAY CRYSTALLOGRAPHY
Descriptor:ANGIOGENIN, PHOSPHATE ION
Authors:Leonidas, D.D., Chavali, G.B., Jardine, A.S., Li, S., Shapiro, R., Acharya, K.R.
Deposit date:2001-04-21
Release date:2001-08-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Binding of Phosphate and Pyrophosphate Ions at the Active Site of Human Angiogenin as Revealed by X-Ray Crystallography
Protein Sci., 10, 2001
1K58
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT D116H
Descriptor:Angiogenin
Authors:Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R.
Deposit date:2001-10-10
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K59
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT Q117G
Descriptor:angiogenin, CITRIC ACID
Authors:Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R.
Deposit date:2001-10-10
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K5A
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN DOUBLE VARIANT I119A/F120A
Descriptor:Angiogenin
Authors:Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R.
Deposit date:2001-10-10
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1K5B
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT DES(121-123)
Descriptor:Angiogenin, CITRIC ACID
Authors:Leonidas, D.D., Shapiro, R., Subbarao, G.V., Russo, A., Acharya, K.R.
Deposit date:2001-10-10
Release date:2002-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic studies on the role of the C-terminal segment of human angiogenin in defining enzymatic potency.
Biochemistry, 41, 2002
1QHC
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CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH 5'-PHOSPHO-2'-DEOXYURIDINE-3'-PYROPHOSPHATE ADENOSINE-3'-PHOSPHATE
Descriptor:PROTEIN (RIBONUCLEASE A), ADENYLATE-3'-PHOSPHATE-[[2'-DEOXY-URIDINE-5'-PHOSPHATE]-3'-PHOSPHATE]
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1999-05-12
Release date:1999-08-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Toward rational design of ribonuclease inhibitors: high-resolution crystal structure of a ribonuclease A complex with a potent 3',5'-pyrophosphate-linked dinucleotide inhibitor.
Biochemistry, 38, 1999
1ABB
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CONTROL OF PHOSPHORYLASE B CONFORMATION BY A MODIFIED COFACTOR: CRYSTALLOGRAPHIC STUDIES ON R-STATE GLYCOGEN PHOSPHORYLASE RECONSTITUTED WITH PYRIDOXAL 5'-DIPHOSPHATE
Descriptor:GLYCOGEN PHOSPHORYLASE B, SULFATE ION, PYRIDOXAL-5'-DIPHOSPHATE, ...
Authors:Leonidas, D.D., Oikonomakos, N.G., Papageorgiou, A.C., Acharya, K.R., Barford, D., Johnson, L.N.
Deposit date:1992-04-09
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Control of phosphorylase b conformation by a modified cofactor: crystallographic studies on R-state glycogen phosphorylase reconstituted with pyridoxal 5'-diphosphate.
Protein Sci., 1, 1992
1AFK
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CRYSTAL STRUCTURE OF RIBONUCLEASE A IN COMPLEX WITH 5'-DIPHOSPHOADENOSINE-3'-PHOSPHATE
Descriptor:RIBONUCLEASE A, 3'-PHOSPHATE-ADENOSINE-5'-DIPHOSPHATE
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1997-03-08
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997
1AFL
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RIBONUCLEASE A IN COMPLEX WITH 5'-DIPHOSPHOADENOSINE 2'-PHOSPHATE AT 1.7 ANGSTROM RESOLUTION
Descriptor:RIBONUCLEASE A, 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, CITRIC ACID
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1997-03-08
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997
1AFU
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STRUCTURE OF RIBONUCLEASE A AT 2.0 ANGSTROMS FROM MONOCLINIC CRYSTALS
Descriptor:RIBONUCLEASE A
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1997-03-14
Release date:1998-03-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of ribonuclease A complexes with 5'-diphosphoadenosine 3'-phosphate and 5'-diphosphoadenosine 2'-phosphate at 1.7 A resolution.
Biochemistry, 36, 1997
1B1E
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT K40Q
Descriptor:HYDROLASE ANGIOGENIN, CITRIC ACID
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1998-11-20
Release date:1999-04-02
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth.
J.Mol.Biol., 285, 1999
1B1I
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN
Descriptor:HYDROLASE ANGIOGENIN, CITRIC ACID
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1998-11-20
Release date:1999-04-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth.
J.Mol.Biol., 285, 1999
1B1J
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CRYSTAL STRUCTURE OF HUMAN ANGIOGENIN VARIANT H13A.
Descriptor:HYDROLASE ANGIOGENIN
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1998-11-20
Release date:1999-04-02
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Refined crystal structures of native human angiogenin and two active site variants: implications for the unique functional properties of an enzyme involved in neovascularisation during tumour growth.
J.Mol.Biol., 285, 1999
1BKZ
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CRYSTAL STRUCTURE OF HUMAN GALECTIN-7
Descriptor:GALECTIN-7
Authors:Leonidas, D.D., Acharya, K.R.
Deposit date:1998-07-13
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the recognition of carbohydrates by human galectin-7.
Biochemistry, 37, 1998
1HI2
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EOSINOPHIL-DERIVED NEUROTOXIN (EDN) - SULPHATE COMPLEX
Descriptor:EOSINOPHIL-DERIVED NEUROTOXIN, SULFATE ION
Authors:Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R.
Deposit date:2001-01-02
Release date:2001-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors
J.Biol.Chem., 276, 2001
1HI3
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EOSINOPHIL-DERIVED NEUROTOXIN (EDN) - ADENOSINE 2'-5'-DIPHOSPHATE COMPLEX
Descriptor:EOSINOPHIL-DERIVED NEUROTOXIN, ADENOSINE-2'-5'-DIPHOSPHATE
Authors:Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R.
Deposit date:2001-01-02
Release date:2001-05-31
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors
J.Biol.Chem., 276, 2001
1HI4
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EOSINOPHIL-DERIVED NEUROTOXIN (EDN) - ADENOSIEN-3'-5'-DIPHOSPHATE COMPLEX
Descriptor:EOSINOPHIL-DERIVED NEUROTOXIN, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R.
Deposit date:2001-01-02
Release date:2001-05-31
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors
J.Biol.Chem., 276, 2001
1HI5
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EOSINOPHIL-DERIVED NEUROTOXIN (EDN) - ADENOSINE-5'-DIPHOSPHATE COMPLEX
Descriptor:EOSINOPHIL-DERIVED NEUROTOXIN, ADENOSINE-5'-DIPHOSPHATE
Authors:Leonidas, D.D., Boix, E., Prill, R., Suzuki, M., Turton, R., Minson, K., Swaminathan, G.J., Youle, R.J., Acharya, K.R.
Deposit date:2001-01-02
Release date:2001-05-31
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Mapping the Ribonucleolytic Active Site of Eosinophil-Derived Neurotoxin (Edn): High Resolution Crystal Structures of Edn Complexes with Adenylic Nucleotide Inhibitors
J.Biol.Chem., 276, 2001
1O0F
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RNASE A IN COMPLEX WITH 3',5'-ADP
Descriptor:Ribonuclease pancreatic, ADENOSINE-3'-5'-DIPHOSPHATE
Authors:Leonidas, D.D., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M.
Deposit date:2003-02-21
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1O0H
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RIBONUCLEASE A IN COMPLEX WITH 5'-ADP
Descriptor:Ribonuclease pancreatic, ADENOSINE-5'-DIPHOSPHATE
Authors:Leonidas, D.D., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M.
Deposit date:2003-02-21
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1O0M
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RIBONUCLEASE A IN COMPLEX WITH URIDINE-2'-PHOSPHATE
Descriptor:Ribonuclease pancreatic, PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER
Authors:Leonidas, D.D., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M.
Deposit date:2003-02-24
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1O0N
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RIBONUCLEASE A IN COMPLEX WITH URIDINE-3'-PHOSPHATE
Descriptor:Ribonuclease pancreatic, 3'-URIDINEMONOPHOSPHATE
Authors:Leonidas, D.D., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M.
Deposit date:2003-02-24
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003
1O0O
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RIBONUCLEASE A IN COMPLEX WITH ADENOSINE-2',5'-DIPHOSPHATE
Descriptor:Ribonuclease pancreatic, ADENOSINE-2'-5'-DIPHOSPHATE
Authors:Leonidas, D.D., Oikonomakos, N.G., Chrysina, E.D., Kosmopoulou, M.N., Vlassi, M.
Deposit date:2003-02-24
Release date:2003-12-09
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors
PROTEIN SCI., 12, 2003