Author results

6HQ6
  • Download 6hq6
  • View 6hq6
Molmil generated image of 6hq6
BACTERIAL BETA-1,3-OLIGOSACCHARIDE PHOSPHORYLASE FROM GH149
Descriptor:Bacterial beta-1,3-oligosaccharide phosphorylase, SULFATE ION, BICINE, ...
Authors:Kuhaudomlarp, S., Stevenson, C.E.M., Lawson, D.M., Field, R.A.
Deposit date:2018-09-24
Release date:2019-06-12
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:The structure of a GH149 beta-(1→3) glucan phosphorylase reveals a new surface oligosaccharide binding site and additional domains that are absent in the disaccharide-specific GH94 glucose-beta-(1→3)-glucose (laminaribiose) phosphorylase.
Proteins, 2019
6HQ8
  • Download 6hq8
  • View 6hq8
Molmil generated image of 6hq8
BACTERIAL BETA-1,3-OLIGOSACCHARIDE PHOSPHORYLASE FROM GH149 WITH LAMINARIHEXAOSE BOUND AT A SURFACE SITE
Descriptor:Beta-1,3-oligosaccharide phosphorylase, SULFATE ION, BICINE, ...
Authors:Kuhaudomlarp, S., Stevenson, C.E.M., Lawson, D.M., Field, R.A.
Deposit date:2018-09-24
Release date:2019-06-12
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:The structure of a GH149 beta-(1→3) glucan phosphorylase reveals a new surface oligosaccharide binding site and additional domains that are absent in the disaccharide-specific GH94 glucose-beta-(1→3)-glucose (laminaribiose) phosphorylase.
Proteins, 2019
6GRG
  • Download 6grg
  • View 6grg
Molmil generated image of 6grg
E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH PRO-MCCB17, ADP AND PHOSPHATE BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GRH
  • Download 6grh
  • View 6grh
Molmil generated image of 6grh
E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH TRUNCATED PRO-MCCB17 BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GRI
  • Download 6gri
  • View 6gri
Molmil generated image of 6gri
E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX
Descriptor:Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, Microcin B17-processing protein McbD, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-11
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GOS
  • Download 6gos
  • View 6gos
Molmil generated image of 6gos
E. COLI MICROCIN SYNTHETASE MCBBCD COMPLEX WITH PRO-MCCB17 BOUND
Descriptor:Bacteriocin microcin B17, Microcin B17-processing protein McbB, Microcin B17-processing protein McbC, ...
Authors:Ghilarov, D., Stevenson, C.E.M., Travin, D.Y., Piskunova, J., Serebryakova, M., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2018-06-04
Release date:2019-01-30
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.
Mol. Cell, 73, 2019
6GGY
  • Download 6ggy
  • View 6ggy
Molmil generated image of 6ggy
PAENIBACILLUS SP. YM1 LAMINARIBIOSE PHOSPHORYLASE WITH SULPHATE BOUND
Descriptor:Laminaribiose phosphorylase, SULFATE ION, 1,2-ETHANEDIOL, ...
Authors:Kuhaudomlarp, S., Walpole, S., Stevenson, C.E.M., Nepogodiev, S.A., Lawson, D.M., Angulo, J., Field, R.A.
Deposit date:2018-05-04
Release date:2018-06-13
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Unravelling the Specificity of Laminaribiose Phosphorylase from Paenibacillus sp. YM-1 towards Donor Substrates Glucose/Mannose 1-Phosphate by Using X-ray Crystallography and Saturation Transfer Difference NMR Spectroscopy.
Chembiochem, 20, 2019
6GH2
  • Download 6gh2
  • View 6gh2
Molmil generated image of 6gh2
PAENIBACILLUS SP. YM1 LAMINARIBIOSE PHOSPHORYLASE WITH ALPHA-GLC-1-PHOSPHATE BOUND
Descriptor:Laminaribiose phosphorylase, SULFATE ION, ALPHA-D-GLUCOSE-1-PHOSPHATE, ...
Authors:Kuhaudomlarp, S., Walpole, S., Stevenson, C.E.M., Nepogodiev, S.A., Lawson, D.M., Angulo, J., Field, R.A.
Deposit date:2018-05-04
Release date:2018-06-13
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Unravelling the Specificity of Laminaribiose Phosphorylase from Paenibacillus sp. YM-1 towards Donor Substrates Glucose/Mannose 1-Phosphate by Using X-ray Crystallography and Saturation Transfer Difference NMR Spectroscopy.
Chembiochem, 20, 2019
6GH3
  • Download 6gh3
  • View 6gh3
Molmil generated image of 6gh3
PAENIBACILLUS SP. YM1 LAMINARIBIOSE PHOSPHORYLASE WITH ALPHA-MAN-1-PHOSPHATE BOUND
Descriptor:Laminaribiose phosphorylase, SULFATE ION, ALPHA-D-MANNOSE 1-PHOSPHATE, ...
Authors:Kuhaudomlarp, S., Walpole, S., Stevenson, C.E.M., Nepogodiev, S.A., Lawson, D.M., Angulo, J., Field, R.A.
Deposit date:2018-05-04
Release date:2018-06-13
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Unravelling the Specificity of Laminaribiose Phosphorylase from Paenibacillus sp. YM-1 towards Donor Substrates Glucose/Mannose 1-Phosphate by Using X-ray Crystallography and Saturation Transfer Difference NMR Spectroscopy.
Chembiochem, 20, 2019
6F9Q
  • Download 6f9q
  • View 6f9q
Molmil generated image of 6f9q
BINARY COMPLEX OF A 7S-CIS-CIS-NEPETALACTOL CYCLASE FROM NEPETA MUSSINII WITH NAD+
Descriptor:7S-cis-cis-nepetalactol cyclase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CHLORIDE ION
Authors:Lichman, B.R., Kamileen, M.O., Titchiner, G., Saalbach, G., Stevenson, C.E.M., Lawson, D.M., O'Connor, S.E.
Deposit date:2017-12-15
Release date:2018-12-12
Last modified:2018-12-19
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis.
Nat. Chem. Biol., 15, 2019
6F94
  • Download 6f94
  • View 6f94
Molmil generated image of 6f94
CRYSTAL STRUCTURE OF E. COLI GYRASEB 24KDA IN COMPLEX WITH 6-[(ETHYLCARBAMOYL)AMINO]-4-[(3-METHYPHENYL)AMINO]-N-(3-METHYPHENYL)PYRIDINE-3-CARBOXAMIDE
Descriptor:DNA gyrase subunit B, 6-(ethylcarbamoylamino)-~{N}-(3-methylphenyl)-4-[(3-methylphenyl)amino]pyridine-3-carboxamide
Authors:Narramore, S.K., Stevenson, C.E.M., Lawson, D.M., Maxwell, A., Fishwick, C.W.G.
Deposit date:2017-12-14
Release date:2019-06-26
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase.
Bioorg.Med.Chem., 2019
6F96
  • Download 6f96
  • View 6f96
Molmil generated image of 6f96
CRYSTAL STRUCTURE OF E. COLI GYRASEB 24KDA IN COMPLEX WITH 6-[(ETHYLCARBAMOYL)AMINO]-4-[(4-METHOXYPHENYL)AMINO]-N-(PYRIDIN-3-YL)PYRIDINE-3-CARBOXAMIDE
Descriptor:DNA gyrase subunit B, 6-(ethylcarbamoylamino)-4-[(4-methoxyphenyl)amino]-~{N}-pyridin-3-yl-pyridine-3-carboxamide
Authors:Narramore, S.K., Stevenson, C.E.M., Lawson, D.M., Maxwell, A., Fishwick, C.W.G.
Deposit date:2017-12-14
Release date:2019-01-30
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase.
Bioorg.Med.Chem., 2019
6F9H
  • Download 6f9h
  • View 6f9h
Molmil generated image of 6f9h
CRYSTAL STRUCTURE OF BARLEY BETA-AMYLASE COMPLEXED WITH 4-S-ALPHA-D-GLUCOPYRANOSYL-(1,4-DIDEOXY-4-THIO-NOJIRIMYCIN)
Descriptor:Beta-amylase, 1,4-dideoxy-4-thio-nojirimycin, ALPHA-D-GLUCOSE, ...
Authors:Moncayo, M.A., Rodrigues, L.L., Stevenson, C.E.M., Ruzanski, C., Rejzek, M., Lawson, D.M., Angulo, J., Field, R.A.
Deposit date:2017-12-14
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Synthesis, biological and structural analysis of prospective glycosyl-iminosugar prodrugs: impact on germination
To be published
6F9J
  • Download 6f9j
  • View 6f9j
Molmil generated image of 6f9j
CRYSTAL STRUCTURE OF BARLEY BETA-AMYLASE COMPLEXED WITH 4-O-ALPHA-D-MANNOPYRANOSYL-(1-DEOXYNOJIRIMYCIN)
Descriptor:Beta-amylase, 1-DEOXYNOJIRIMYCIN, ALPHA-D-MANNOSE, ...
Authors:Moncayo, M.A., Rodrigues, L.L., Stevenson, C.E.M., Ruzanski, C., Rejzek, M., Lawson, D.M., Angulo, J., Field, R.A.
Deposit date:2017-12-14
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Synthesis, biological and structural analysis of prospective glycosyl-iminosugar prodrugs: impact on germination
To be published
6F9L
  • Download 6f9l
  • View 6f9l
Molmil generated image of 6f9l
CRYSTAL STRUCTURE OF BARLEY BETA-AMYLASE COMPLEXED WITH 3-DEOXY-3-FLUORO-MALTOSE
Descriptor:Beta-amylase, (2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(2~{R},3~{R},4~{R},5~{S},6~{S})-4-fluoranyl-2-(hydroxymethyl)-5,6-bis(oxidanyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol, CHLORIDE ION
Authors:Tantanarat, K., Stevenson, C.E.M., Rejzek, M., Lawson, D.M., Field, R.A.
Deposit date:2017-12-14
Release date:2019-01-30
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Crystal structure of Barley Beta-Amylase complexed with 3-Deoxy-3-fluoro-maltose
To be published
6F8J
  • Download 6f8j
  • View 6f8j
Molmil generated image of 6f8j
CRYSTAL STRUCTURE OF E. COLI GYRASEB 24KDA IN COMPLEX WITH 6-[(ETHYLCARBAMOYL)AMINO]-4-(1H-PYRAZOL-1-YL)-N-(PYRIDIN-3-YL)PYRIDINE-3-CARBOXAMIDE
Descriptor:DNA gyrase subunit B, 6-(ethylcarbamoylamino)-4-pyrazol-1-yl-~{N}-pyridin-3-yl-pyridine-3-carboxamide
Authors:Narramore, S.K., Stevenson, C.E.M., Lawson, D.M., Maxwell, A., Fishwick, C.W.G.
Deposit date:2017-12-13
Release date:2019-06-26
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase.
Bioorg.Med.Chem., 2019
6F86
  • Download 6f86
  • View 6f86
Molmil generated image of 6f86
CRYSTAL STRUCTURE OF E. COLI GYRASEB 24KDA IN COMPLEX WITH 4-(4-BROMO-1H-PYRAZOL-1-YL)-6-[(ETHYLCARBAMOYL)AMINO]-N-(PYRIDIN-3-YL)PYRIDINE-3-CARBOXAMIDE
Descriptor:DNA gyrase subunit B, 4-(4-bromanylpyrazol-1-yl)-6-(ethylcarbamoylamino)-~{N}-pyridin-3-yl-pyridine-3-carboxamide
Authors:Narramore, S.K., Stevenson, C.E.M., Lawson, D.M., Maxwell, A., Fishwick, C.W.G.
Deposit date:2017-12-12
Release date:2019-06-26
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:New insights into the binding mode of pyridine-3-carboxamide inhibitors of E. coli DNA gyrase.
Bioorg.Med.Chem., 2019
5O98
  • Download 5o98
  • View 5o98
Molmil generated image of 5o98
BINARY COMPLEX OF CATHARANTHUS ROSEUS VITROSAMINE SYNTHASE WITH NADP+
Descriptor:Alcohol dehydrogenase 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Stavrinides, A.K., Tatsis, E.C., Dang, T.T., Caputi, L., Stevenson, C.E.M., Lawson, D.M., Schneider, B., O'Connor, S.E.
Deposit date:2017-06-16
Release date:2018-02-21
Last modified:2018-05-16
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Discovery of a Short-Chain Dehydrogenase from Catharanthus roseus that Produces a New Monoterpene Indole Alkaloid.
Chembiochem, 19, 2018
5NZ7
  • Download 5nz7
  • View 5nz7
Molmil generated image of 5nz7
CLOSTRIDIUM THERMOCELLUM CELLODEXTRIN PHOSPHORYLASE LIGAND FREE FORM
Descriptor:Cellodextrin phosphorylase, CHLORIDE ION
Authors:O'Neill, E.C., Pergolizzi, G., Stevenson, C.E.M., Lawson, D.M., Nepogodiev, S.A., Field, R.A.
Deposit date:2017-05-12
Release date:2017-08-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis.
Carbohydr. Res., 451, 2017
5NZ8
  • Download 5nz8
  • View 5nz8
Molmil generated image of 5nz8
CLOSTRIDIUM THERMOCELLUM CELLODEXTRIN PHOSPHORYLASE WITH CELLOTETRAOSE AND PHOSPHATE BOUND
Descriptor:Cellodextrin phosphorylase, BETA-D-GLUCOSE, PHOSPHATE ION
Authors:O'Neill, E.C., Pergolizzi, G., Stevenson, C.E.M., Lawson, D.M., Nepogodiev, S.A., Field, R.A.
Deposit date:2017-05-12
Release date:2017-08-09
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cellodextrin phosphorylase from Ruminiclostridium thermocellum: X-ray crystal structure and substrate specificity analysis.
Carbohydr. Res., 451, 2017
5NJ5
  • Download 5nj5
  • View 5nj5
Molmil generated image of 5nj5
E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH PHOSPHATE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ZINC ION, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJ9
  • Download 5nj9
  • View 5nj9
Molmil generated image of 5nj9
E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH DRVY ANGIOTENSIN FRAGMENT BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ASP-ARG-VAL-TYR, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJA
  • Download 5nja
  • View 5nja
Molmil generated image of 5nja
E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH ANGIOTENSIN ANALOGUE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, HIS-PRO-PHE, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJB
  • Download 5njb
  • View 5njb
Molmil generated image of 5njb
E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E WITH ACTINONIN BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, ZINC ION, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017
5NJC
  • Download 5njc
  • View 5njc
Molmil generated image of 5njc
E. COLI MICROCIN-PROCESSING METALLOPROTEASE TLDD/E (TLDD E263A MUTANT) WITH HEXAPEPTIDE BOUND
Descriptor:Metalloprotease TldD, Metalloprotease PmbA, VAL-LEU-GLU-ASP-ARG-ILE, ...
Authors:Ghilarov, D., Serebryakova, M., Stevenson, C.E.M., Hearnshaw, S.J., Volkov, D., Maxwell, A., Lawson, D.M., Severinov, K.
Deposit date:2017-03-28
Release date:2017-10-04
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:The Origins of Specificity in the Microcin-Processing Protease TldD/E.
Structure, 25, 2017