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4ZS0
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HUMAN AURORA A CATALYTIC DOMAIN BOUND TO SB-6-OH
Descriptor:Aurora kinase A, 5-hydroxy-1'H-1,2'-bibenzimidazol-2(3H)-one
Authors:Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
Deposit date:2015-05-12
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
4ZTQ
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HUMAN AURORA A CATALYTIC DOMAIN BOUND TO FK932
Descriptor:Aurora kinase A, (2Z,5Z)-2-[(4-ethylphenyl)imino]-3-(2-methoxyethyl)-5-(pyridin-4-ylmethylidene)-1,3-thiazolidin-4-one, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
Deposit date:2015-05-14
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
4ZTR
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HUMAN AURORA A CATALYTIC DOMAIN BOUND TO FK1141
Descriptor:Aurora kinase A, 6-({4-[(Z)-{(2Z)-2-[(4-ethylphenyl)imino]-3-methyl-4-oxo-1,3-thiazolidin-5-ylidene}methyl]pyridin-2-yl}amino)pyridine-3-carboxylic acid
Authors:Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
Deposit date:2015-05-15
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016
4ZTS
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HUMAN AURORA A CATALYTIC DOMAIN BOUND TO FK1142
Descriptor:Aurora kinase A, (2Z,5Z)-2-[(4-ethylphenyl)imino]-3-methyl-5-[(2-{[4-(1H-tetrazol-5-yl)phenyl]amino}pyridin-4-yl)methylidene]-1,3-thiazolidin-4-one, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Marcaida, M.J., Kilchmann, F., Schick, T., Reymond, J.L.
Deposit date:2015-05-15
Release date:2016-07-20
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Discovery of a Selective Aurora A Kinase Inhibitor by Virtual Screening.
J.Med.Chem., 59, 2016