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6HWF
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YEAST 20S PROTEASOME BETA2-G45A MUTANT IN COMPLEX WITH ONX 0914
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HWE
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YEAST 20S PROTEASOME BETA2-G45A MUTANT IN COMPLEX WITH CARFILZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HWD
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YEAST 20S PROTEASOME BETA2-G45A MUTANT IN COMPLEX WITH BORTEZOMIB
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HWC
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YEAST 20S PROTEASOME BETA2-G45A MUTANT
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HWB
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YEAST 20S PROTEASOME IN COMPLEX WITH 44B
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HWA
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YEAST 20S PROTEASOME IN COMPLEX WITH 43
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW9
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YEAST 20S PROTEASOME IN COMPLEX WITH 41B
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW8
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YEAST 20S PROTEASOME IN COMPLEX WITH 39
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW7
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YEAST 20S PROTEASOME IN COMPLEX WITH 29
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW6
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YEAST 20S PROTEASOME IN COMPLEX WITH 20
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW5
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YEAST 20S PROTEASOME IN COMPLEX WITH 18
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW4
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YEAST 20S PROTEASOME IN COMPLEX WITH 16
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW3
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YEAST 20S PROTEASOME IN COMPLEX WITH 13
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HW0
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YEAST 20S PROTEASOME IN COMPLEX WITH 7
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVY
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YEAST 20S PROTEASOME IN COMPLEX WITH 5 (7- AND 6-MEMBERED RING)
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVX
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YEAST 20S PROTEASOME IN COMPLEX WITH 4
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVW
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 43
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVV
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 39
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVU
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 29
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVT
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 20
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVS
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 18
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVR
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 16
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-11
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HVA
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 13
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HV7
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 7
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019
6HV5
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YEAST 20S PROTEASOME WITH HUMAN BETA2I (1-53) IN COMPLEX WITH 4
Descriptor:Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, Proteasome subunit alpha type-4, ...
Authors:Huber, E.M., Groll, M.
Deposit date:2018-10-10
Release date:2019-01-30
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-Based Design of Inhibitors Selective for Human Proteasome beta 2c or beta 2i Subunits.
J.Med.Chem., 62, 2019