8T3W
| Structure of Bre1-nucleosome complex - state2 | Descriptor: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | Authors: | Zhao, F, Hicks, C.W, Wolberger, C. | Deposit date: | 2023-06-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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8T3T
| Structure of Bre1-nucleosome complex - state3 | Descriptor: | 601 DNA strand 1, 601 DNA strand 2, E3 ubiquitin-protein ligase BRE1, ... | Authors: | Zhao, F, Hicks, C.W, Wolberger, C. | Deposit date: | 2023-06-07 | Release date: | 2023-10-18 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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8T3Y
| Structure of Bre1-nucleosome complex - state1 | Descriptor: | 601 DNA Strand 1, 601 DNA Strand 2, E3 ubiquitin-protein ligase BRE1, ... | Authors: | Zhao, F, Hicks, C.W, Wolberger, C. | Deposit date: | 2023-06-08 | Release date: | 2023-10-18 | Last modified: | 2023-11-22 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Mechanism of histone H2B monoubiquitination by Bre1. Nat.Struct.Mol.Biol., 30, 2023
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5ZJW
| Crystal Structure of PAK4 in complex with inhibitor CZg353 | Descriptor: | (3Z)-N-[(1S)-2-hydroxy-1-phenylethyl]-3-[(1H-imidazol-2-yl)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxamide, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | Authors: | Zhao, F, Li, H. | Deposit date: | 2018-03-22 | Release date: | 2019-04-03 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Crystal Structure of PAK4 in complex with inhibitor CZg353 To be published
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6IYV
| Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with ertapenem adduct | Descriptor: | (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhao, F, Li, D.F, Wang, D.C. | Deposit date: | 2018-12-17 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2for ertapenem than for imipenem. Biochem. Biophys. Res. Commun., 510, 2019
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7E9M
| Crystal Structure of Spindlin1 bound to SPINDOC Docpep3 | Descriptor: | Peptide from Spindlin interactor and repressor of chromatin-binding protein, Spindlin-1 | Authors: | Zhao, F, Li, H. | Deposit date: | 2021-03-04 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular basis for SPINDOC-Spindlin1 engagement and its role in transcriptional inhibition to be published
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7EA1
| Crystal Structure of Spindlin1 bound to SPINDOC Docpep2 | Descriptor: | Peptide from Spindlin interactor and repressor of chromatin-binding protein, Spindlin-1 | Authors: | Zhao, F, Li, H. | Deposit date: | 2021-03-05 | Release date: | 2022-06-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Molecular basis for SPINDOC-Spindlin1 engagement and its role in transcriptional inhibition to be published
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7FCT
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7BU9
| Crystal Structure of Spindlin1-H3(K4me3-K9me2) complex | Descriptor: | H3(K4me3-K9me2) peptide, Spindlin-1 | Authors: | Zhao, F, Li, H. | Deposit date: | 2020-04-05 | Release date: | 2020-10-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.502 Å) | Cite: | Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1. J.Biol.Chem., 295, 2020
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7XC8
| Crystal structure of cotton alpha-like expansin GhEXLA1 | Descriptor: | Beta-expansin, DI(HYDROXYETHYL)ETHER, GLYCEROL | Authors: | Zhao, F, Men, S, Xue, Y, Tu, L.L, Yin, P, Zhang, X.L. | Deposit date: | 2022-03-23 | Release date: | 2023-05-17 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystal structure of cotton alpha-like expansin GhEXLA1 To Be Published
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7BQZ
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5XVA
| Crystal Structure of PAK4 in complex with inhibitor CZH216 | Descriptor: | ETHANOL, Serine/threonine-protein kinase PAK 4, [6-chloranyl-4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]-[(3R)-3-methylpiperazin-1-yl]methanone | Authors: | Zhao, F, Li, H. | Deposit date: | 2017-06-27 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.847 Å) | Cite: | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors. J. Med. Chem., 61, 2018
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5XVG
| Crystal Structure of PAK4 in complex with inhibitor CZH226 | Descriptor: | 1,2-ETHANEDIOL, ETHANOL, Serine/threonine-protein kinase PAK 4, ... | Authors: | Zhao, F, Li, H. | Deposit date: | 2017-06-27 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors. J. Med. Chem., 61, 2018
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5XVF
| Crystal Structure of PAK4 in complex with inhibitor CZH062 | Descriptor: | 2-(4-azanylpiperidin-1-yl)-6-chloranyl-N-(1-methylimidazol-4-yl)quinazolin-4-amine, Serine/threonine-protein kinase PAK 4 | Authors: | Zhao, F, Li, H. | Deposit date: | 2017-06-27 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.655 Å) | Cite: | Structure-Based Design of 6-Chloro-4-aminoquinazoline-2-carboxamide Derivatives as Potent and Selective p21-Activated Kinase 4 (PAK4) Inhibitors. J. Med. Chem., 61, 2018
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1ZZ5
| Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | Descriptor: | 13,15-DIAMINO-2-(AMINOMETHYL)-3,4,9,12-TETRAHYDROXYHEXADECAHYDRO-2H-7,10-EPOXYPYRANO[2,3-B][1,10,4]BENZODIOXAZACYCLODODECIN-8-YL 2,6-DIAMINO-2,6-DIDEOXYHEXOPYRANOSIDE, 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3', ... | Authors: | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | Deposit date: | 2005-06-13 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular recognition of RNA by neomycin and a restricted neomycin derivative Angew.Chem.Int.Ed.Engl., 44, 2005
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2A04
| Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | Descriptor: | 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3', MAGNESIUM ION, ... | Authors: | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | Deposit date: | 2005-06-15 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Molecular recognition of RNA by neomycin and a restricted neomycin derivative Angew.Chem.Int.Ed.Engl., 44, 2005
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1ZX7
| Molecular Recognition of RNA by Neomycin and a Restricted Neomycin Derivative | Descriptor: | 5'-R(*CP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*AP*CP*C)-3', 5'-R(*GP*UP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*CP*GP*G)-3' | Authors: | Zhao, Q, Zhao, F, Blount, K.F, Han, Q, Tor, Y, Hermann, T. | Deposit date: | 2005-06-07 | Release date: | 2005-09-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular recognition of RNA by neomycin and a restricted neomycin derivative Angew.Chem.Int.Ed.Engl., 44, 2005
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6IYW
| Crystal sturucture of L,D-transpeptidase LdtMt2 from Mycobacterium tuberculosis in complex with Imipenem adduct | Descriptor: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, GLYCEROL, L,D-transpeptidase 2 | Authors: | Li, D.F, Zhao, F, Wang, D.C. | Deposit date: | 2018-12-17 | Release date: | 2019-02-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The 1-beta-methyl group confers a lower affinity of l,d-transpeptidase LdtMt2 for ertapenem than for imipenem. Biochem. Biophys. Res. Commun., 510, 2019
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4FMC
| EspG-Rab1 complex | Descriptor: | ALUMINUM FLUORIDE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMA
| EspG structure | Descriptor: | ACETIC ACID, EspG protein, FORMIC ACID, ... | Authors: | Shao, F, Zhu, Y, Hu, L. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FME
| EspG-Rab1-Arf6 complex | Descriptor: | ADP-ribosylation factor 6, ALUMINUM FLUORIDE, EspG protein, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMB
| VirA-Rab1 complex structure | Descriptor: | ALUMINUM FLUORIDE, Cysteine protease-like virA, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2012-10-03 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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4FMD
| EspG-Rab1 complex structure at 3.05 A | Descriptor: | ALUMINUM FLUORIDE, DI(HYDROXYETHYL)ETHER, EspG protein, ... | Authors: | Shao, F, Zhu, Y. | Deposit date: | 2012-06-16 | Release date: | 2012-09-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses. Cell(Cambridge,Mass.), 150, 2012
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8HAW
| An auto-activation mechanism of plant non-specific phospholipase C | Descriptor: | CALCIUM ION, GLYCEROL, Non-specific phospholipase C4, ... | Authors: | Zhao, F, Fan, R.Y, Guan, Z.Y, Guo, L, Yin, P. | Deposit date: | 2022-10-26 | Release date: | 2023-01-25 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C. Nat Commun, 14, 2023
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8HAV
| An auto-activation mechanism of plant non-specific phospholipase C | Descriptor: | DI(HYDROXYETHYL)ETHER, GLYCEROL, Non-specific phospholipase C4 | Authors: | Zhao, F, Fan, R.Y, Guan, Z.Y, Guo, L, Yin, P. | Deposit date: | 2022-10-26 | Release date: | 2023-01-25 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights into the mechanism of phospholipid hydrolysis by plant non-specific phospholipase C. Nat Commun, 14, 2023
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