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5MG2
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CRYSTAL STRUCTURE OF THE SECOND BROMODOMAIN OF HUMAN TAF1 IN COMPLEX WITH BAY-299 CHEMICAL PROBE
Descriptor:Transcription initiation factor TFIID subunit 1, 1,2-ETHANEDIOL, 6-(3-oxidanylpropyl)-2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione
Authors:Tallant, C., Bouche, L., Holton, S.J., Fedorov, O., Siejka, P., Picaud, S., Krojer, T., Srikannathasan, V., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Hartung, I.V., Haendler, B., Muller, S., Huber, K.V.M., Structural Genomics Consortium (SGC)
Deposit date:2016-11-20
Release date:2017-05-03
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.
J. Med. Chem., 60, 2017
5N49
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BRPF2 IN COMPLEX WITH COMPOUND 7
Descriptor:Bromodomain-containing protein 1, 2-(1,3,6-trimethyl-2-oxidanylidene-benzimidazol-5-yl)benzo[de]isoquinoline-1,3-dione
Authors:Bouche, L., Christ, C.D., Siegel, S., Fernandez-Montalvan, A.E., Holton, S.J., Fedorov, O., ter Laak, A., Sugawara, T., Stoeckigt, D., Tallant, C., Bennett, J., Monteiro, O., Saez, L.D., Siejka, P., Meier, J., Puetter, V., Weiske, J., Mueller, S., Huber, K.V.M., Hartung, I.V., Haendler, B.
Deposit date:2017-02-10
Release date:2017-05-03
Last modified:2017-05-24
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Benzoisoquinolinediones as Potent and Selective Inhibitors of BRPF2 and TAF1/TAF1L Bromodomains.
J. Med. Chem., 60, 2017
1CYN
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CYCLOPHILIN B COMPLEXED WITH [D-(CHOLINYLESTER)SER8]-CYCLOSPORIN
Descriptor:PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B, CYCLOSPORIN A
Authors:Mikol, V., Kallen, J., Walkinshaw, M.D.
Deposit date:1995-05-22
Release date:1996-01-29
Last modified:2018-09-12
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:X-Ray Structure of a Cyclophilin B/Cyclosporin Complex: Comparison with Cyclophilin a and Delineation of its Calcineurin-Binding Domain.
Proc.Natl.Acad.Sci.USA, 91, 1994
2C9O
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3D STRUCTURE OF THE HUMAN RUVB-LIKE HELICASE RUVBL1
Descriptor:RUVB-LIKE 1, ADENOSINE-5'-DIPHOSPHATE
Authors:Matias, P.M., Gorynia, S., Donner, P., Carrondo, M.A.
Deposit date:2005-12-14
Release date:2006-10-23
Last modified:2019-03-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of the human AAA+ protein RuvBL1.
J. Biol. Chem., 281, 2006