Author results

4BJH
  • Download 4bjh
  • View 4bjh
Molmil generated image of 4bjh
CRYSTAL STRUCTURE OF THE AQUIFEX REACTOR COMPLEX FORMED BY DIHYDROOROTASE (H180A, H232A) WITH DIHYDROOROTATE AND ASPARTATE TRANSCARBAMOYLASE WITH N-(PHOSPHONACETYL)-L-ASPARTATE (PALA)
Descriptor:DIHYDROOROTASE, ASPARTATE CARBAMOYLTRANSFERASE, ZINC ION, ...
Authors:Edwards, B.F.P., Martin, P.D., Grimley, E., Vaishnav, A., Fernando, R., Brunzelle, J.S., Cordes, M., Evans, H.G., Evans, D.R.
Deposit date:2013-04-18
Release date:2013-12-18
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:The Mononuclear Metal Center of Type-I Dihydroorotase from Aquifex Aeolicus.
Bmc Biochem., 14, 2013
6DUM
  • Download 6dum
  • View 6dum
Molmil generated image of 6dum
ALDH1A1 N121S IN COMPLEX WITH 6-{[(3-FLUOROPHENYL)METHYL]SULFANYL}-2-(OXETAN-3-YL)-5-PHENYL-2,5-DIHYDRO-4H-PYRAZOLO[3,4-D]PYRIMIDIN-4-ONE (COMPOUND 13G)
Descriptor:Retinal dehydrogenase 1, YTTERBIUM (III) ION, 6-{[(3-fluorophenyl)methyl]sulfanyl}-2-(oxetan-3-yl)-5-phenyl-2,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, ...
Authors:Buchman, C.D., Hurley, T.D.
Deposit date:2018-06-21
Release date:2019-05-01
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy.
J.Med.Chem., 61, 2018