Author results

2OPG
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THE CRYSTAL STRUCTURE OF THE 10TH PDZ DOMAIN OF MPDZ
分子名称:Multiple PDZ domain protein, SODIUM ION
著者Gileadi, C., Phillips, C., Elkins, J., Papagrigoriou, E., Ugochukwu, E., Gorrec, F., Savitsky, P., Umeano, C., Berridge, G., Gileadi, O., Salah, E., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-01-29
公開日2007-02-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the 10th PDZ domain of MPDZ
To be Published
2Q3H
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THE CRYSTAL STRUCTURE OF RHOUA IN THE GDP-BOUND STATE.
分子名称:Ras homolog gene family, member U, MAGNESIUM ION, ...
著者Gileadi, C., Yang, X., Papagrigoriou, E., Elkins, J., Zhao, Y., Bray, J., Gileadi, O., Umeano, C., Ugochukwu, E., Uppenberg, J., Bunkoczi, G., von Delft, F., Pike, A.C.W., Phillips, C., Savitsky, P., Fedorov, O., Edwards, A., Weigelt, J., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-05-30
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The crystal structure of RhouA in the GDP-bound state.
To be Published
2Q3G
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STRUCTURE OF THE PDZ DOMAIN OF HUMAN PDLIM7 BOUND TO A C-TERMINAL EXTENSION FROM HUMAN BETA-TROPOMYOSIN
分子名称:PDZ and LIM domain protein 7, 1,2-ETHANEDIOL, CHLORIDE ION
著者Gileadi, C., Papagrigoriou, E., Elkins, J., Burgess-Brown, N., Salah, E., Gileadi, O., Umeano, C., Bunkoczi, G., von Delft, F., Uppenberg, J., Pike, A.C.W., Arrowsmith, C.H., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-05-30
公開日2007-06-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Structure of the PDZ domain of human PDLIM7 bound to a C-terminal extension from human beta-tropomyosin
To be Published
2ODE
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CRYSTAL STRUCTURE OF THE HETERODIMERIC COMPLEX OF HUMAN RGS8 AND ACTIVATED GI ALPHA 3
分子名称:Guanine nucleotide-binding protein G(k) subunit alpha, Regulator of G-protein signaling 8, TETRAFLUOROALUMINATE ION, ...
著者Gileadi, C., Soundararajan, M., Turnbull, A.P., Elkins, J.M., Papagrigoriou, E., Pike, A.C.W., Bunkoczi, G., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-12-22
公開日2007-02-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2OZF
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THE CRYSTAL STRUCTURE OF THE 2ND PDZ DOMAIN OF THE HUMAN NHERF-1 (SLC9A3R1)
分子名称:Ezrin-radixin-moesin-binding phosphoprotein 50
著者Phillips, C., Papagrigoriou, E., Gileadi, C., Fedorov, O., Elkins, J., Berridge, G., Turnbull, A.P., Gileadi, O., Schoch, G., Smee, C., Bray, J., Savitsky, P., Uppenberg, J., von Delft, F., Gorrec, F., Umeano, C., Salah, E., Colebrook, S., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-02-26
公開日2007-03-13
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the 2nd PDZ domain of the human NHERF-1 (SLC9A3R1)
To be Published
2OCS
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THE CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF HUMAN NHERF-2 (SLC9A3R2)
分子名称:Na(+)/H(+) exchange regulatory cofactor NHE-RF2, THIOCYANATE ION, 1,2-ETHANEDIOL
著者Papagrigoriou, E., Phillips, C., Gileadi, C., Elkins, J., Salah, E., Berridge, G., Savitsky, P., Gorrec, F., Umeano, C., Ugochukwu, E., Gileadi, O., Burgess, N., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-12-21
公開日2007-01-16
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the first PDZ domain of human NHERF-2 (SLC9A3R2)
To be Published
2P0A
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THE CRYSTAL STRUCTURE OF HUMAN SYNAPSIN III (SYN3) IN COMPLEX WITH AMPPNP
分子名称:Synapsin-3, CHLORIDE ION, SULFATE ION, ...
著者Turnbull, A.P., Phillips, C., Pike, A.C.W., Elkins, J.M., Gileadi, C., Salah, E., Niesen, F.H., Burgess, N., Gileadi, O., Gorrec, F., Umeano, C., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C.H., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2007-02-28
公開日2007-03-27
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of human synapsin III (SYN3) in complex with AMPPNP
To be Published
2PNT
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN GRASP (GRP1) IN COMPLEX WITH THE C-TERMINAL PEPTIDE OF THE METABOTROPIC GLUTAMATE RECEPTOR TYPE 1
分子名称:General receptor for phosphoinositides 1-associated scaffold protein, CHLORIDE ION
著者Elkins, J., Papagrigoriou, E., Cooper, C., Gileadi, C., Uppenberg, J., Bray, J., von Delft, F., Pike, A.C.W., Ugochukwu, E., Umeano, C., Gileadi, O., Edwards, A., Arrowsmith, C.H., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-04-25
公開日2007-05-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.148 Å)
主引用文献Crystal structure of the PDZ domain of human GRASP (GRP1) in complex with the C-terminal peptide of the metabotropic glutamate receptor type 1.
To be Published
2C2H
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CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP
分子名称:RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 3, GUANOSINE-5'-DIPHOSPHATE, CALCIUM ION, ...
著者Debreczeni, J.E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., von Delft, F., Doyle, D., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A.
登録日2005-09-29
公開日2005-10-13
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal Structure of the Human Rac3 in Complex with Gdp
To be Published
2ERY
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THE CRYSTAL STRUCTURE OF THE RAS RELATED PROTEIN RRAS2 (RRAS2) IN THE GDP BOUND STATE
分子名称:Ras-related protein R-Ras2, MAGNESIUM ION, GUANOSINE-5'-DIPHOSPHATE
著者Salah, E., Schoch, G., Turnbull, A., Papagrigoriou, E., Soundararajan, M., Burgess, N., Elkins, J., Gileadi, C., Gileadi, O., von Delft, F., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2005-10-25
公開日2005-11-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of the Ras related protein RRas2 (RRAS2) in the GDP bound state
To be Published
2G0N
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THE CRYSTAL STRUCTURE OF THE HUMAN RAC3 IN COMPLEX WITH GDP AND CHLORIDE
分子名称:Ras-related C3 botulinum toxin substrate 3, MAGNESIUM ION, CHLORIDE ION, ...
著者Ugochukwu, E., Yang, X., Zao, Y., Elkins, J., Gileadi, C., Burgess, N., Colebrook, S., Gileadi, O., Fedorov, O., Bunkoczi, G., Sundstrom, M., Arrowsmith, C., Weigelt, J., Edwards, A., von Delft, F., Doyle, D., Structural Genomics Consortium (SGC)
登録日2006-02-13
公開日2006-05-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Crystal Structure of the Human RAC3 in complex with GDP and Chloride
To be Published
2PKT
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CRYSTAL STRUCTURE OF THE HUMAN CLP-36 (PDLIM1) BOUND TO THE C-TERMINAL PEPTIDE OF HUMAN ALPHA-ACTININ-1
分子名称:PDZ and LIM domain protein 1, CALCIUM ION, CHLORIDE ION, ...
著者Uppenberg, J., Gileadi, C., Elkins, J., Bray, J., Burgess-Brown, N., Salah, E., Gileadi, O., Bunkoczi, G., Ugochukwu, E., Umeano, C., von Delft, F., Weigelt, J., Arrowsmith, C.H., Edwards, A., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2007-04-18
公開日2007-05-08
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1.
To be Published
2REY
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CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF HUMAN DISHEVELLED 2 (HOMOLOGOUS TO DROSOPHILA DSH)
分子名称:Segment polarity protein dishevelled homolog DVL-2
著者Papagrigoriou, E., Gileadi, C., Elkins, J., Cooper, C., Ugochukwu, E., Turnbull, A., Pike, A.C.W., Gileadi, O., von Delft, F., Sundstrom, M., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Doyle, D., Structural Genomics Consortium (SGC)
登録日2007-09-27
公開日2007-10-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structure of the PDZ domains of human dishevelled 2 (homologous to Drosophila dsh).
To be Published
3ZWF
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CRYSTAL STRUCTURE OF HUMAN TRNASE Z, SHORT FORM (ELAC1).
分子名称:ZINC PHOSPHODIESTERASE ELAC PROTEIN 1, 1,2-ETHANEDIOL, ZINC ION, ...
著者Allerston, C.K., Krojer, T., Berridge, G., Burgess-Brown, N., Chaikuad, A., Chalk, R., Elkins, J.M., Gileadi, C., Latwiel, S.V.A., Savitsky, P., Vollmar, M., Arrowsmith, C.H., Weigelt, J., Edwards, A., Bountra, C., von Delft, F., Gileadi, O.
登録日2011-07-29
公開日2011-08-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Human Trnase Z, Short Form (Elac1).
To be Published
2IHD
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CRYSTAL STRUCTURE OF HUMAN REGULATOR OF G-PROTEIN SIGNALING 8, RGS8
分子名称:Regulator of G-protein signaling 8, CHLORIDE ION
著者Turnbull, A.P., Papagrigoriou, E., Ugochukwu, E., Salah, E., Gileadi, C., Burgess, N., Bhatia, C., Gileadi, O., Bray, J., Elkins, J., von Delft, F., Weigelt, J., Edwards, A., Arrowsmith, C., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-09-26
公開日2006-11-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2J1L
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CRYSTAL STRUCTURE OF HUMAN RHO-RELATED GTP-BINDING PROTEIN RHOD
分子名称:RHO-RELATED GTP-BINDING PROTEIN RHOD, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION
著者Pike, A.C.W., Johansson, C., Gileadi, C., Niesen, F.H., Sobott, F., Schoch, G., Elkins, J., Smee, C., Gorrec, F., Watt, S., Bray, J., Turnbull, A.P., von Delft, F., Arrowsmith, C., Edwards, A., Weigelt, J., Sundstrom, M., Doyle, D.
登録日2006-08-14
公開日2006-09-18
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of Human Rho-Related GTP-Binding Protein Rhod
To be Published
2O2T
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THE CRYSTAL STRUCTURE OF THE 1ST PDZ DOMAIN OF MPDZ
分子名称:Multiple PDZ domain protein
著者Papagrigoriou, E., Gileadi, C., Phillips, C., Johansson, C., Salah, E., Savitsky, P., Gorrec, F., Umeano, C., Berridge, G., Pike, A.C.W., Elkins, J., Edwards, A., Arrowsmith, C., Weigelt, J., Sundstrom, M., Doyle, D.A., Structural Genomics Consortium (SGC)
登録日2006-11-30
公開日2006-12-12
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure of the 1st PDZ domain of MPDZ
To be Published
2XDP
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CRYSTAL STRUCTURE OF THE TUDOR DOMAIN OF HUMAN JMJD2C
分子名称:LYSINE-SPECIFIC DEMETHYLASE 4C, SULFATE ION
著者Yue, W.W., Gileadi, C., Krojer, T., Weisbach, H., Ugochukwu, E., Daniel, M., Phillips, C., Chaikuad, A., von Delft, F., Allerston, C., Arrowsmith, C., Weigelt, J., Edwards, A., Bountra, C., Oppermann, U.
登録日2010-05-06
公開日2010-06-09
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal Structure of the Tudor Domain of Human Jmjd2C
To be Published
5A3P
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN PLU1 (JARID1B).
分子名称:LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ...
著者Nowak, R., Srikannathasan, V., Johansson, C., Gileadi, C., Tallant, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., von Delft, F., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Oppermann, U.
登録日2015-06-02
公開日2015-06-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.008 Å)
主引用文献Structural Analysis of Human Kdm5B Guides Histone Demethylase Inhibitor Development.
Nat.Chem.Biol., 12, 2016
5FY4
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH SUCCINATE
分子名称:LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ...
著者Nowak, R., Srikannathasan, V., Johansson, C., Gileadi, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., von Delft, F., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Oppermann, U.
登録日2016-03-04
公開日2017-03-22
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with Succinate
To be Published
5FY5
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH FUMARATE
分子名称:LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ...
著者Nowak, R., Srikannathasan, V., Johansson, C., Gileadi, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., von Delft, F., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Oppermann, U.
登録日2016-03-04
公開日2017-03-22
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.47 Å)
主引用文献Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with Fumarate
To be Published
5FY9
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH PYRUVATE
分子名称:LYSINE-SPECIFIC DEMETHYLASE 5B, MANGANESE (II) ION, ZINC ION, ...
著者Nowak, R., Srikannathasan, V., Johansson, C., Gileadi, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., von Delft, F., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Oppermann, U.
登録日2016-03-04
公開日2017-03-22
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with Pyruvate
To be Published
5FYB
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH MC1648
分子名称:LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ...
著者Nowak, R., Srikannathasan, V., Rotili, D., Johansson, C., Gileadi, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., von Delft, F., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Oppermann, U.
登録日2016-03-05
公開日2017-03-29
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with Mc1648
To be Published
5FYS
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH D-2-HYDROXYGLUTARATE
分子名称:LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ...
著者Nowak, R., Kopec, J., Johansson, C., Gileadi, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., von Delft, F., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Oppermann, U.
登録日2016-03-09
公開日2017-03-22
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with D-2-Hydroxyglutarate
To be Published
5FYT
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN JARID1B IN COMPLEX WITH 3D FRAGMENT (5-FLUORO-2-OXO-2,3-DIHYDRO-1H-INDOL-3-YL)ACETIC ACID (N09996A)
分子名称:LYSINE-SPECIFIC DEMETHYLASE 5B, ZINC ION, MANGANESE (II) ION, ...
著者Nowak, R., Krojer, T., Johansson, C., Pearce, N., Gileadi, C., Kupinska, K., Strain-Damerell, C., Szykowska, A., Burgess-Brown, N.A., Arrowsmith, C.H., Bountra, C., Edwards, A.M., von Delft, F., Brennan, P.E., Oppermann, U.
登録日2016-03-09
公開日2016-03-23
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with N09996A
To be Published