Author results

5WRV
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COMPLEX STRUCTURE OF HUMAN SRP72/SRP68
Descriptor:ACETATE ION, GLYCEROL, SODIUM ION, ...
Authors:Gao, Y., Chen, Z.
Deposit date:2016-12-04
Release date:2017-06-21
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
5WRW
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STRUCTURE OF HUMAN APO-SRP72
Descriptor:SULFATE ION, Signal recognition particle subunit SRP72
Authors:Gao, Y., Chen, Z.
Deposit date:2016-12-04
Release date:2017-06-21
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation
J Mol Cell Biol, 9, 2017
3UBU
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CRYSTAL STRUCTURE OF AGKISACUCETIN, A GPIB-BINDING SNACLEC (SNAKE C-TYPE LECTIN) THAT INHIBITS PLATELET
Descriptor:Agglucetin subunit alpha-1, Agglucetin subunit beta-2, GLYCEROL, ...
Authors:Gao, Y., Ge, H., Chen, H., Li, H., Liu, Y., Niu, L., Teng, M.
Deposit date:2011-10-25
Release date:2012-04-11
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of agkisacucetin, a Gpib-binding snake C-type lectin that inhibits platelet adhesion and aggregation.
Proteins, 2012
5IRX
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STRUCTURE OF TRPV1 IN COMPLEX WITH DKTX AND RTX, DETERMINED IN LIPID NANODISC
Descriptor:(2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ...
Authors:Gao, Y., Cao, E., Julius, D., Cheng, Y.
Deposit date:2016-03-14
Release date:2016-05-25
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (2.95 Å)
Cite:TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5IRZ
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STRUCTURE OF TRPV1 DETERMINED IN LIPID NANODISC
Descriptor:(2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(pentanoyloxy)propan-2-yl decanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ...
Authors:Gao, Y., Cao, E., Julius, D., Cheng, Y.
Deposit date:2016-03-15
Release date:2016-05-25
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5IS0
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STRUCTURE OF TRPV1 IN COMPLEX WITH CAPSAZEPINE, DETERMINED IN LIPID NANODISC
Descriptor:Transient receptor potential cation channel subfamily V member 1, capsazepine
Authors:Gao, Y., Cao, E., Julius, D., Cheng, Y.
Deposit date:2016-03-15
Release date:2016-05-25
Last modified:2017-09-13
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
2DU9
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CRYSTAL STRUCTURE OF THE TRANSCRIPTIONAL FACTOR FROM C.GLUTAMICUM
Descriptor:(4S)-2-METHYL-2,4-PENTANEDIOL, Predicted transcriptional regulators
Authors:Gao, Y., Yao, M., Tanaka, I.
Deposit date:2006-07-20
Release date:2007-07-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:The structures of transcription factor CGL2947 from Corynebacterium glutamicum in two crystal forms: A novel homodimer assembling and the implication for effector-binding mode
Protein Sci., 16, 2007
1CL4
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NUCLEOCAPSID PROTEIN FROM MASON-PFIZER MONKEY VIRUS (MPMV)
Descriptor:PROTEIN (GAG POLYPROTEIN), ZINC ION
Authors:Gao, Y., Kaluarachchi, K., Giedroc, D.P.
Deposit date:1999-05-06
Release date:1999-05-11
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and backbone dynamics of Mason-Pfizer monkey virus (MPMV) nucleocapsid protein.
Protein Sci., 7, 1998
4GWS
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CRYSTAL STRUCTURE OF AMP COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH FILLED CENTRAL CAVITY
Descriptor:ADENOSINE MONOPHOSPHATE, FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fructose 2,6-bisphosphate Inhibition
To be Published
4GWU
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CRYSTAL STRUCTURE OF FRU 2,6-BISPHOSPHATE COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH FILLED CENTRAL CAVITY
Descriptor:FRUCTOSE-2,6-DIPHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Method:X-RAY DIFFRACTION (3 Å)
Cite:Hydrophobic Central Cavity in Fructose-1,6-bisphosphatase is Essential for the Synergism in AMP/Fru 2,6-bisphosphate Inhibition
To be Published
4GWW
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CRYSTAL STRUCTURE OF PRODUCT COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH BLOCKED SUBUNIT PAIR ROTATION
Descriptor:FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-11
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GWX
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CRYSTAL STRUCTURE OF PRODUCT COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH RESTRAINED SUBUNIT PAIR ROTATION
Descriptor:FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GWY
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CRYSTAL STRUCTURE OF AMP COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH BLOCKED SUBUNIT PAIR ROTATION
Descriptor:ADENOSINE MONOPHOSPHATE, FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-11
Method:X-RAY DIFFRACTION (3 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GWZ
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CRYSTAL STRUCTURE OF AMP COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH RESTRAINED SUBUNIT PAIR ROTATION
Descriptor:ADENOSINE MONOPHOSPHATE, FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Functional Importance of Subunit Pair Rotation in Regulation of Tetrameric Mammalian Fructose-1,6-bisphosphatase
To be Published
4GX3
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PRODUCT COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH MUTATION R22M REVEAL A T-STATE CONFORMATION
Descriptor:FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, MAGNESIUM ION, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4GX4
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AMP COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH MUTATION R22M
Descriptor:ADENOSINE MONOPHOSPHATE, FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4GX6
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AMP COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH MUTATION E192Q
Descriptor:ADENOSINE MONOPHOSPHATE, FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-03
Release date:2013-09-04
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4H45
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PRODUCT COMPLEXES OF PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE WITH MUTATION E192Q
Descriptor:FRUCTOSE-6-PHOSPHATE, Fructose-1,6-bisphosphatase 1, PHOSPHATE ION, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-16
Release date:2013-09-18
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Dimer-dimer Interface in Porcine Liver Fructose-1,6-bisphosphatase is Essential in Cooperative Binding of AMP
To be Published
4H46
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CRYSTAL STRUCTURE OF AMP COMPLEXES OF NEM MODIFIED PORCINE LIVER FRUCTOSE-1,6-BISPHOSPHATASE
Descriptor:1-ETHYL-PYRROLIDINE-2,5-DIONE, ADENOSINE MONOPHOSPHATE, FRUCTOSE-6-PHOSPHATE, ...
Authors:Gao, Y., Honzatko, R.B.
Deposit date:2012-09-16
Release date:2013-09-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Fluorescent 2',3'-O-(2,4,6-trinitrophenyl) (TNP)-AMP Is an Active Site Inhibitor for Porcine Liver Fructose-1,6-bisphosphatase Rather Than Allosteric Inhibitor
To be Published
5KFA
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: GROUND STATE AT PH7.0 (K+ MES) WITH 1 CA2+ ION
Descriptor:2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y., Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.51 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFB
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: REACTION WITH 1 MM MN2+ FOR 90S
Descriptor:2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y., Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFC
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: REACTION WITH 1 MM MN2+ FOR 180S
Descriptor:2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y., Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFD
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: REACTION WITH 1 MM MN2+ FOR 300S
Descriptor:2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y., Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFE
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: REACTION WITH 1 MM MN2+ FOR 600S
Descriptor:2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
Authors:Gao, Y., Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFF
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HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: REACTION WITH 1 MM MN2+ FOR 1800S
Descriptor:2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
Authors:Gao, Y., Yang, W.
Deposit date:2016-06-12
Release date:2016-06-22
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
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