Author results

2VUJ
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ENVIRONMENTALLY ISOLATED GH11 XYLANASE
Descriptor:GH11 XYLANASE, GLYCEROL
Authors:Dumon, C., Varvak, A., Wall, M.A., Flint, J.E., Lewis, R.J., Lakey, J.H., Luginbuhl, P., Healey, S., Todaro, T., DeSantis, G., Sun, M., Parra-Gessert, L., Tan, X., Weiner, D.P., Gilbert, H.J.
Deposit date:2008-05-26
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
2VUL
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THERMOSTABLE MUTANT OF ENVIRONMENTALLY ISOLATED GH11 XYLANASE
Descriptor:GH11 XYLANASE, SULFATE ION, DODECAETHYLENE GLYCOL
Authors:Dumon, C., Varvak, A., Wall, M.A., Flint, J.E., Lewis, R.J., Lakey, J.H., Luginbuhl, P., Healey, S., Todaro, T., Desantis, G., Sun, M., Parra-Gessert, L., Tan, X., Weiner, D.P., Gilbert, H.J.
Deposit date:2008-05-27
Release date:2008-06-17
Last modified:2014-06-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Engineering Hyperthermostability Into a Gh11 Xylanase is Mediated by Subtle Changes to Protein Structure.
J.Biol.Chem., 283, 2008
1W8F
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PSEUDOMONAS AERUGINOSA LECTIN II (PA-IIL)COMPLEXED WITH LACTO-N-NEO- FUCOPENTAOSE V(LNPFV)
Descriptor:PSEUDOMONAS AERUGINOSA LECTIN II, SULFATE ION, CALCIUM ION, ...
Authors:Perret, S., Sabin, C., Dumon, C., Budova, M., Gautier, C., Galanina, O., Ilia, S., Bovin, N., Nicaise, M., Desmadril, M., Gilboa-Garber, N., Wimmerova, M., Mitchell, E.P., Imberty, A.
Deposit date:2004-09-21
Release date:2005-03-31
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (1.05 Å)
Cite:Structural Basis for the Interaction between Human Milk Oligosaccharides and the Bacterial Lectin Pa-Iil of Pseudomonas Aeruginosa.
Biochem.J., 389, 2005
1W8H
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STRUCTURE OF PSEUDOMONAS AERUGINOSA LECTIN II (PA-IIL)COMPLEXED WITH LEWISA TRISACCHARIDE
Descriptor:PSEUDOMONAS AERUGINOSA LECTIN II, CALCIUM ION, ALPHA-L-FUCOSE, ...
Authors:Perret, S., Sabin, C., Dumon, C., Budova, M., Gautier, C., Galanina, O., Ilia, S., Bovin, N., Nicaise, M., Desmadril, M., Gilboa-Garber, N., Wimmerova, M., Mitchell, E.P., Imberty, A.
Deposit date:2004-09-21
Release date:2005-03-31
Last modified:2013-01-30
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural Basis for the Interaction between Human Milk Oligosaccharides and the Bacterial Lectin Pa-Iil of Pseudomonas Aeruginosa.
Biochem.J., 389, 2005
2W46
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CBM35 FROM CELLVIBRIO JAPONICUS ABF62
Descriptor:ESTERASE D, CALCIUM ION, SODIUM ION
Authors:Montainer, C., Lammerts van Bueren, A., Dumon, C., Flint, J.E., Correia, M.A., Prates, J.A., Firbank, S.J., Lewis, R.J., Grondin, G.G., Ghinet, M.G., Gloster, T.M., Herve, C., Knox, J.P., Talbot, B.G., Turkenburg, J.P., Kerovuo, J., Brzezinski, R., Fontes, C.M.G.A., Davies, G.J., Boraston, A.B., Gilbert, H.J.
Deposit date:2008-11-21
Release date:2009-01-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W47
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CLOSTRIDIUM THERMOCELLUM CBM35 IN COMPLEX WITH DELTA-4,5- ANHYDROGALACTURONIC ACID
Descriptor:LIPOLYTIC ENZYME, G-D-S-L, CALCIUM ION, ...
Authors:Montainer, C., Lammerts van Bueren, A., Dumon, C., Flint, J.E., Correia, M.A., Prates, J.A., Firbank, S.J., Lewis, R.J., Grondin, G.G., Ghinet, M.G., Gloster, T.M., Herve, C., Knox, J.P., Talbot, B.G., Turkenburg, J.P., Kerovuo, J., Brzezinski, R., Fontes, C.M.G.A., Davies, G.J., Boraston, A.B., Gilbert, H.J.
Deposit date:2008-11-21
Release date:2009-01-27
Last modified:2017-06-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2W87
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XYL-CBM35 IN COMPLEX WITH GLUCURONIC ACID CONTAINING DISACCHARIDE.
Descriptor:ESTERASE D, CALCIUM ION, D-GLUCURONIC ACID, ...
Authors:Montainer, C., Bueren, A.L.v., Dumon, C., Flint, J.E., Correia, M.A., Prates, J.A., Firbank, S.J., Lewis, R.J., Grondin, G.G., Ghinet, M.G., Gloster, T.M., Herve, C., Knox, J.P., Talbot, B.G., Turkenburg, J.P., Kerovuo, J., Brzezinski, R., Fontes, C.M.G.A., Davies, G.J., Boraston, A.B., Gilbert, H.J.
Deposit date:2009-01-14
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
2VJX
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2007-12-14
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VL4
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (2S,3S,4R,5R)-2,3,4-TRIHYDROXY-5-HYDROXYMETHYL-PIPERIDINE, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-01-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VMF
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-01-25
Release date:2008-04-01
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VO5
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (1R,4R,5R,7R,8R)-2-Benzyl-5-hydroxymethyl-2-aza-bicyclo[2.2.2]octane-4,7,8-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-02-08
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VOT
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (5R,6R,7S,8R)-6,7,8-trihydroxy-5-(hydroxymethyl)-2-[(phenylamino)methyl]-5,6,7,8-tetrahydro-1H-imidazo[1,2-a]pyridin-4-ium, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.N., Offen, W.A., Smith, N., Dumon, C., Moreland, C., Gratien, J., Heck, M.-P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-02-20
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VQT
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, (2Z,3R,4S,5R,6R)-2-[(2-aminoethyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-18
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VQU
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STRUCTURAL AND BIOCHEMICAL EVIDENCE FOR A BOAT-LIKE TRANSITION STATE IN BETA-MANNOSIDASES
Descriptor:BETA-MANNOSIDASE, 1,2-ETHANEDIOL, (2R,3S,4R,5R)-5-(HYDROXYMETHYL)PIPERIDINE-2,3,4-TRIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-18
Release date:2008-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2VR4
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TRANSITION-STATE MIMICRY IN MANNOSIDE HYDROLYSIS: CHARACTERISATION OF TWENTY SIX INHIBITORS AND INSIGHT INTO BINDING FROM LINEAR FREE ENERGY RELATIONSHIPS AND 3-D STRUCTURE
Descriptor:BETA-MANNOSIDASE, (2Z,3R,4S,5R,6R)-2-[(4-aminobutyl)imino]-6-(hydroxymethyl)piperidine-3,4,5-triol, 1,2-ETHANEDIOL, ...
Authors:Tailford, L.E., Offen, W.A., Smith, N.L., Dumon, C., Moreland, C., Gratien, J., Heck, M.P., Stick, R.V., Bleriot, Y., Vasella, A., Gilbert, H.J., Davies, G.J.
Deposit date:2008-03-25
Release date:2008-04-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural and Biochemical Evidence for a Boat-Like Transition State in Beta-Mannosidases.
Nat.Chem.Biol., 4, 2008
2CNC
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FAMILY 10 XYLANASE
Descriptor:ENDOXYLANASE, CHLORIDE ION, XYLOPYRANOSE, ...
Authors:Xie, H., Flint, J., Vardakou, M., Lakey, J.H., Lewis, R.J., Gilbert, H.J., Dumon, C.
Deposit date:2006-05-19
Release date:2006-06-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Probing the Structural Basis for the Difference in Thermostability Displayed by Family 10 Xylanases.
J.Mol.Biol., 360, 2006
2JE8
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STRUCTURE OF A BETA-MANNOSIDASE FROM BACTEROIDES THETAIOTAOMICRON
Descriptor:BETA-MANNOSIDASE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ...
Authors:Tailford, L.E., Money, V.A., Smith, N.L., Dumon, C., Davies, G.J., Gilbert, H.J.
Deposit date:2007-01-16
Release date:2007-02-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Mannose Foraging by Bacteroides Thetaiotaomicron: Structure and Specificity of the Beta-Mannosidase, Btman2A.
J.Biol.Chem., 282, 2007
2VG9
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CRYSTAL STRUCTURE OF LOOP SWAP MUTANT OF NECALLIMASTIX PATRICIARUM XYN11A
Descriptor:BIFUNCTIONAL ENDO-1,4-BETA-XYLANASE A, CADMIUM ION, ACETATE ION
Authors:Vardakou, M., Dumon, C., Flint, J.E., Murray, J.W., Christakopoulos, P., Weiner, D.P., Juge, N., Lewis, R.J., Gilbert, H.J.
Deposit date:2007-11-09
Release date:2007-12-25
Last modified:2013-06-19
Method:X-RAY DIFFRACTION (2 Å)
Cite:Understanding the Structural Basis for Substrate and Inhibitor Recognition in Eukaryotic Gh11 Xylanases.
J.Mol.Biol., 375, 2008
2VGD
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CRYSTAL STRUCTURE OF ENVIRONMENTAL ISOLATED GH11 IN COMPLEX WITH XYLOBIOSE AND FERULOYL-ARABINO-XYLOTRIOSE
Descriptor:ENXYN11A, SODIUM ION, BETA-D-XYLOPYRANOSE, ...
Authors:Vardakou, M., Dumon, C., Flint, J.E., Murray, J.W., Christakopoulos, P., Weiner, D.P., Juge, N., Lewis, R.J., Gilbert, H.J.
Deposit date:2007-11-12
Release date:2007-12-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Understanding the Structural Basis for Substrate and Inhibitor Recognition in Eukaryotic Gh11 Xylanases.
J.Mol.Biol., 375, 2008
2WZS
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STRUCTURE OF THE FAMILY GH92 INVERTING MANNOSIDASE BT3990 FROM BACTEROIDES THETAIOTAOMICRON VPI-5482 IN COMPLEX WITH MANNOIMIDAZOLE
Descriptor:PUTATIVE ALPHA-1,2-MANNOSIDASE, CALCIUM ION, (5R,6R,7S,8R)-5-(HYDROXYMETHYL)-5,6,7,8-TETRAHYDROIMIDAZO[1,2-A]PYRIDINE-6,7,8-TRIOL, ...
Authors:Zhu, Y., Suits, M.D.L., Thompson, A., Chavan, S., Dinev, Z., Dumon, C., Smith, N., Moremen, K.W., Xiang, Y., Siriwardena, A., Williams, S.J., Gilbert, H.J., Davies, G.J.
Deposit date:2009-12-02
Release date:2009-12-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Mechanistic Insights Into a Ca2+-Dependent Family of A-Mannosidases in a Human Gut Symbiont.
Nat.Chem.Biol., 6, 2010
4N1I
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CRYSTAL STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE UMABF62A FROM USTILAGO MAIDYS
Descriptor:alpha-L-arabinofuranosidase UmAbf62A, CALCIUM ION, GLYCEROL, ...
Authors:Siguier, B., Dumon, C., Mourey, L., Tranier, S.
Deposit date:2013-10-04
Release date:2014-01-15
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1 Å)
Cite:First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
4N2R
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CRYSTAL STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE UMABF62A FROM USTILAGO MAYDIS IN COMPLEX WITH L-ARABINOFURANOSE
Descriptor:alpha-L-arabinofuranosidase UmAbf62A, CALCIUM ION, beta-L-arabinofuranose, ...
Authors:Siguier, B., Dumon, C., Mourey, L., Tranier, S.
Deposit date:2013-10-06
Release date:2014-01-15
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
4N2Z
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CRYSTAL STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE PAABF62A FROM PODOSPORA ANSERINA IN COMPLEX WITH CELLOTRIOSE
Descriptor:GH62 arabinofuranosidase, CALCIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
Authors:Siguier, B., Dumon, C., Mourey, L., Tranier, S.
Deposit date:2013-10-06
Release date:2014-01-15
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
4N4B
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CRYSTAL STRUCTURE OF THE ALPHA-L-ARABINOFURANOSIDASE PAABF62A FROM PODOSPORA ANSERINA
Descriptor:GH62 arabinofuranosidase, CALCIUM ION, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Siguier, B., Dumon, C., Mourey, L., Tranier, S.
Deposit date:2013-10-08
Release date:2014-01-15
Last modified:2014-03-12
Method:X-RAY DIFFRACTION (1.44 Å)
Cite:First Structural Insights into alpha-L-Arabinofuranosidases from the Two GH62 Glycoside Hydrolase Subfamilies.
J.Biol.Chem., 289, 2014
2W1W
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NATIVE STRUCTURE OF A FAMILY 35 CARBOHYDRATE BINDING MODULE FROM CLOSTRIDIUM THERMOCELLUM
Descriptor:LIPOLYTIC ENZYME, G-D-S-L, CALCIUM ION, ...
Authors:Gloster, T.M., Davies, G.J., Correia, M., Prates, J., Fontes, C., Gilbert, H.J.
Deposit date:2008-10-21
Release date:2009-01-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.
Proc.Natl.Acad.Sci.USA, 106, 2009
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