1QHH
| STRUCTURE OF DNA HELICASE WITH ADPNP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, PROTEIN (PCRA (SUBUNIT)) | Authors: | Soultanas, P, Dillingham, M.S, Velankar, S.S, Wigley, D.B. | Deposit date: | 1999-05-14 | Release date: | 1999-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase. J.Mol.Biol., 290, 1999
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1QHG
| STRUCTURE OF DNA HELICASE MUTANT WITH ADPNP | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ATP-DEPENDENT HELICASE PCRA, MAGNESIUM ION | Authors: | Soultanas, P, Dillingham, M.S, Velankar, S.S, Wigley, D.B. | Deposit date: | 1999-05-14 | Release date: | 1999-07-13 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | DNA binding mediates conformational changes and metal ion coordination in the active site of PcrA helicase. J.Mol.Biol., 290, 1999
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2PJR
| HELICASE PRODUCT COMPLEX | Descriptor: | DNA (5'-D(*AP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*C)-3'), DNA (5'-D(*TP*TP*TP*TP*T)-3'), ... | Authors: | Velankar, S.S, Soultanas, P, Dillingham, M.S, Subramanya, H.S, Wigley, D.B. | Deposit date: | 1999-03-12 | Release date: | 1999-04-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism. Cell(Cambridge,Mass.), 97, 1999
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3PJR
| HELICASE SUBSTRATE COMPLEX | Descriptor: | 5'-D(*CP*GP*AP*GP*CP*AP*CP*TP*GP*C)-3', 5'-D(*GP*CP*AP*GP*TP*GP*CP*TP*CP*GP*TP*TP*TP*TP*T)-3', ADENOSINE-5'-TRIPHOSPHATE, ... | Authors: | Velankar, S.S, Soultanas, P, Dillingham, M.S, Subramanya, H.S, Wigley, D.B. | Deposit date: | 1999-03-12 | Release date: | 1999-04-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism Cell(Cambridge,Mass.), 97, 1999
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1W36
| RecBCD:DNA complex | Descriptor: | CALCIUM ION, DNA HAIRPIN, EXODEOXYRIBONUCLEASE V ALPHA CHAIN, ... | Authors: | Singleton, M.R, Dillingham, M.S, Gaudier, M, C Kowalczykowski, S, Wigley, D.B. | Deposit date: | 2004-07-13 | Release date: | 2004-11-04 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Crystal Structure of Recbcd Enzyme Reveals a Machine for Processing DNA Breaks Nature, 432, 2004
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8B1U
| RecBCD-DNA in complex with the phage protein Abc2 and host PpiB | Descriptor: | Anti-RecBCD protein 2, DNA (70-MER), MAGNESIUM ION, ... | Authors: | Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S. | Deposit date: | 2022-09-12 | Release date: | 2022-12-28 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub. Elife, 11, 2022
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8B1R
| RecBCD in complex with the phage protein gp5.9 | Descriptor: | MAGNESIUM ION, Probable RecBCD inhibitor gp5.9, RecBCD enzyme subunit RecB, ... | Authors: | Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S. | Deposit date: | 2022-09-12 | Release date: | 2022-12-28 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub. Elife, 11, 2022
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8B1T
| RecBCD-DNA in complex with the phage protein Abc2 | Descriptor: | Anti-RecBCD protein 2, DNA (70-MER), MAGNESIUM ION, ... | Authors: | Wilkinson, M, Wilkinson, O.J, Feyerherm, C, Fletcher, E.E, Wigley, D.B, Dillingham, M.S. | Deposit date: | 2022-09-12 | Release date: | 2022-12-28 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub. Elife, 11, 2022
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5NOC
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5MBV
| Cryo-EM structure of Lambda Phage protein GamS bound to RecBCD. | Descriptor: | Host-nuclease inhibitor protein gam, RecBCD enzyme subunit RecB, RecBCD enzyme subunit RecC, ... | Authors: | Wilkinson, M, Chaban, Y, Wigley, D.B. | Deposit date: | 2016-11-08 | Release date: | 2017-01-11 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones. Elife, 5, 2016
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5DMA
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3U44
| Crystal structure of AddAB-DNA complex | Descriptor: | ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease subunit A, DNA (36-MER), ... | Authors: | Saikrishnan, K, Krajewski, W, Wigley, D. | Deposit date: | 2011-10-07 | Release date: | 2012-03-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex. Embo J., 31, 2012
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3U4Q
| Structure of AddAB-DNA complex at 2.8 angstroms | Descriptor: | 1,2-ETHANEDIOL, ATP-dependent helicase/deoxyribonuclease subunit B, ATP-dependent helicase/nuclease subunit A, ... | Authors: | Saikrishnan, K, Krajewski, W, Wigley, D. | Deposit date: | 2011-10-10 | Release date: | 2012-03-21 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Insights into Chi recognition from the structure of an AddAB-type helicase-nuclease complex. Embo J., 31, 2012
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6G26
| The crystal structure of the Burkholderia pseudomallei HicAB complex | Descriptor: | 1,2-ETHANEDIOL, HicA, HicB, ... | Authors: | Winter, A.J, Isupov, M.N, Williams, C, Crump, M.P. | Deposit date: | 2018-03-22 | Release date: | 2018-10-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | The molecular basis of protein toxin HicA-dependent binding of the protein antitoxin HicB to DNA. J. Biol. Chem., 293, 2018
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6G1N
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6G1C
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4CEJ
| Crystal structure of AddAB-DNA-ADPNP complex at 3 Angstrom resolution | Descriptor: | ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ... | Authors: | Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D. | Deposit date: | 2013-11-11 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites. Nature, 508, 2014
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4CEH
| Crystal structure of AddAB with a forked DNA substrate | Descriptor: | ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ... | Authors: | Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D. | Deposit date: | 2013-11-11 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.24 Å) | Cite: | Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites. Nature, 508, 2014
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4CEI
| Crystal structure of ADPNP-bound AddAB with a forked DNA substrate | Descriptor: | ATP-DEPENDENT HELICASE/DEOXYRIBONUCLEASE SUBUNIT B, ATP-DEPENDENT HELICASE/NUCLEASE SUBUNIT A, DNA, ... | Authors: | Krajewski, W.W, Wilkinson, M, Fu, X, Cronin, N.B, Wigley, D. | Deposit date: | 2013-11-11 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites. Nature, 508, 2014
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3K70
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