Author results

6BZK
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SOLUTION STRUCTURE OF KTI55
Descriptor:M protein
Authors:Castellino, F.J., Qiu, C., Yuan, Y.
Deposit date:2017-12-24
Release date:2019-01-16
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:Solution structure of truncated PAM
To Be Published
5TBG
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-R1B MUTANT
Descriptor:Conantokin-R1B
Authors:Castellino, F.J., Yuan, Y.
Deposit date:2016-09-12
Release date:2017-06-28
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors.
Biochemistry, 55, 2016
5TBQ
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-R1B MUTANT
Descriptor:Conantokin
Authors:Castellino, F.J., Yuan, Y.
Deposit date:2016-09-12
Release date:2017-06-28
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors.
Biochemistry, 55, 2016
5TBR
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-R1B MUTANT
Descriptor:Conantokin-R1-B
Authors:Castellino, F.J., Yuan, Y.
Deposit date:2016-09-12
Release date:2017-06-28
Last modified:2017-09-27
Method:SOLUTION NMR
Cite:Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors.
Biochemistry, 55, 2016
1I5K
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STRUCTURE AND BINDING DETERMINANTS OF THE RECOMBINANT KRINGLE-2 DOMAIN OF HUMAN PLASMINOGEN TO AN INTERNAL PEPTIDE FROM A GROUP A STREPTOCOCCAL SURFACE PROTEIN
Descriptor:PLASMINOGEN, M PROTEIN
Authors:Rios-Steiner, J.L., Schenone, M., Mochalkin, I., Tulinsky, A., Castellino, F.J.
Deposit date:2001-02-27
Release date:2001-08-01
Last modified:2011-11-16
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein.
J.Mol.Biol., 308, 2001
6BZL
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SOLUTION STRUCTURE OF VEK75
Descriptor:M protein
Authors:Qiu, C., Yuan, Y., Castellino, F.J.
Deposit date:2017-12-24
Release date:2019-01-16
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:The C-Domain Repeats in Plasminogen-binding Group A Streptococcal M-Protein are Essential Determinants for its Dimerization
To Be Published
1KI0
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THE X-RAY STRUCTURE OF HUMAN ANGIOSTATIN
Descriptor:ANGIOSTATIN, BICINE
Authors:Abad, M.C., Arni, R.K., Grella, D.K., Castellino, F.J., Tulinsky, A., Geiger, J.H.
Deposit date:2001-12-02
Release date:2002-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:The X-ray crystallographic structure of the angiogenesis inhibitor angiostatin.
J.Mol.Biol., 318, 2002
2DOH
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THE X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE ANGIOGENESIS INHIBITOR, ANGIOSTATIN, BOUND A TO A PEPTIDE FROM THE GROUP A STREPTOCOCCAL SURFACE PROTEIN PAM
Descriptor:Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM, 1,4-DIETHYLENE DIOXIDE
Authors:Cnudde, S.E., Prorok, M., Castellino, F.J., Geiger, J.H.
Deposit date:2006-04-29
Release date:2006-12-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2DOI
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THE X-RAY CRYSTALLOGRAPHIC STRUCTURE OF THE ANGIOGENESIS INHIBITOR, ANGIOSTATIN, BOUND TO A PEPTIDE FROM THE GROUP A STREPTOCOCCUS PROTEIN PAM
Descriptor:Angiostatin, Plasminogen-binding group A streptococcal M-like protein PAM
Authors:Cnudde, S.E., Prorok, M., Castellino, F.J., Geiger, J.H.
Deposit date:2006-04-29
Release date:2006-12-05
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:X-ray crystallographic structure of the angiogenesis inhibitor, angiostatin, bound to a peptide from the group A streptococcal surface protein PAM
Biochemistry, 45, 2006
2DPQ
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THE CRYSTAL STRUCTURES OF THE CALCIUM-BOUND CON-G AND CON-T(K7GAMMA) DIMERIC PEPTIDES DEMONSTRATE A NOVEL METAL-DEPENDENT HELIX-FORMING MOTIF
Descriptor:Conantokin-G, CHLORIDE ION, CALCIUM ION
Authors:Cnudde, S.E., Prorok, M., Dai, Q., Castellino, F.J., Geiger, J.H.
Deposit date:2006-05-13
Release date:2007-04-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif
J.Am.Chem.Soc., 129, 2007
2DPR
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THE CRYSTAL STRUCTURES OF THE CALCIUM-BOUND CON-G AND CON-T(K7GLU) DIMERIC PEPTIDES DEMONSTRATE A NOVEL METAL-DEPENDENT HELIX-FORMING MOTIF
Descriptor:Conantokin-T, CALCIUM ION
Authors:Cnudde, S.E., Prorok, M., Dai, Q., Castellino, F.J., Geiger, J.H.
Deposit date:2006-05-13
Release date:2007-04-24
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The crystal structures of the calcium-bound con-G and con-T[K7gamma] dimeric peptides demonstrate a metal-dependent helix-forming motif
J.Am.Chem.Soc., 129, 2007
2KNF
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SOLUTION STRUCTURE AND FUNCTIONAL CHARACTERIZATION OF HUMAN PLASMINOGEN KRINGLE 5
Descriptor:Plasminogen
Authors:Battistel, M.D., Grishaev, A., An, S.A., Castellino, F.J., Llinas, M.
Deposit date:2009-08-21
Release date:2009-10-27
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure and functional characterization of human plasminogen kringle 5.
Biochemistry, 48, 2009
2MYZ
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-R1B MUTANT
Descriptor:Conantokin-R1-B
Authors:Kunda, S., Yuan, Y., Balsara, R.D., Zajicek, J., Castellino, F.J.
Deposit date:2015-02-04
Release date:2015-06-17
Last modified:2015-08-05
Method:SOLUTION NMR
Cite:Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
2MZK
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN RLB
Descriptor:Conantokin-R1-B
Authors:Kunda, S., Yuan, Y., Balsara, R.D., Zajicek, J., Castellino, F.J.
Deposit date:2015-02-14
Release date:2015-06-17
Last modified:2015-08-05
Method:SOLUTION NMR
Cite:Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
2MZL
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-G MUTANT
Descriptor:Conantokin-R1-B
Authors:Kunda, S., Yuan, Y., Balsara, R.D., Zajicek, J., Castellino, F.J.
Deposit date:2015-02-14
Release date:2015-06-17
Last modified:2015-08-05
Method:SOLUTION NMR
Cite:Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
2MZM
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THE SOLUTION STRUCTURE OF THE MAGNESIUM-BOUND CONANTOKIN-G
Descriptor:Conantokin-R1-B
Authors:Kunda, S., Yuan, Y., Balsara, R.D., Zajicek, J., Castellino, F.J.
Deposit date:2015-02-14
Release date:2015-06-17
Last modified:2015-08-05
Method:SOLUTION NMR
Cite:Hydroxyproline-induced Helical Disruption in Conantokin Rl-B Affects Subunit-selective Antagonistic Activities toward Ion Channels of N-Methyl-d-aspartate Receptors.
J.Biol.Chem., 290, 2015
5HPG
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STRUCTURE AND LIGAND DETERMINANTS OF THE RECOMBINANT KRINGLE 5 DOMAIN OF HUMAN PLASMINOGEN
Descriptor:PLASMINOGEN
Authors:Tulinsky, A., Mochalkin, I., Castellino, F.J.
Deposit date:1997-09-19
Release date:1998-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure and ligand binding determinants of the recombinant kringle 5 domain of human plasminogen.
Biochemistry, 37, 1998
6BZJ
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SOLUTION STRUCTURE OF AGL55
Descriptor:M protein
Authors:Qiu, C., Yuan, Y., Castellino, F.J.
Deposit date:2017-12-24
Release date:2019-01-16
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:The C-Domain Repeats in Plasminogen-binding Group A Streptococcal M-Protein are Essential Determinants for its Dimerization
To Be Published
5V4U
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SOLUTION STRUCTURE OF VKK38 BOUND TO PLASMINOGEN KRINGLE 2
Descriptor:M protein
Authors:Yuan, Y., Castellino, F.
Deposit date:2017-03-10
Release date:2017-07-26
Last modified:2017-09-20
Method:SOLUTION NMR
Cite:Conformationally organized lysine isosteres in Streptococcus pyogenes M protein mediate direct high-affinity binding to human plasminogen.
J. Biol. Chem., 292, 2017
2KJ4
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SOLUTION STRUCTURE OF THE COMPLEX OF VEK-30 AND PLASMINOGEN KRINGLE 2
Descriptor:plasminogen, VEK-30
Authors:Wang, M., Zajicek, J., Prorok, M., Castellin, F.J.
Deposit date:2009-05-21
Release date:2009-10-20
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Solution structure of the complex of VEK-30 and plasminogen kringle 2.
J.Struct.Biol., 169, 2010
1CEA
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THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH EACA (EPSILON-AMINOCAPROIC ACID)
Descriptor:PLASMINOGEN, 6-AMINOHEXANOIC ACID
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1995-12-03
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
Biochemistry, 35, 1996
1CEB
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THE STRUCTURE OF THE NON-COVALENT COMPLEX OF RECOMBINANT KRINGLE 1 DOMAIN OF HUMAN PLASMINOGEN WITH AMCHA (TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID)
Descriptor:PLASMINOGEN, TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACID
Authors:Tulinsky, A., Mathews, I.I.
Deposit date:1995-12-03
Release date:1996-04-03
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.07 Å)
Cite:Crystal structures of the recombinant kringle 1 domain of human plasminogen in complexes with the ligands epsilon-aminocaproic acid and trans-4-(aminomethyl)cyclohexane-1-carboxylic Acid.
Biochemistry, 35, 1996
1PKR
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THE STRUCTURE OF RECOMBINANT PLASMINOGEN KRINGLE 1 AND THE FIBRIN BINDING SITE
Descriptor:PLASMINOGEN, CHLORIDE ION
Authors:Wu, T.-P., Tulinsky, A.
Deposit date:1993-08-03
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:The structure of recombinant plasminogen kringle 1 and the fibrin binding site.
Blood Coagulation Fibrinolysis, 5, 1994