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1HNN
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CRYSTAL STRUCTURE OF HUMAN PNMT COMPLEXED WITH SK&F 29661 AND ADOHCY(SAH)
Descriptor:PHENYLETHANOLAMINE N-METHYLTRANSFERASE, S-ADENOSYL-L-HOMOCYSTEINE, 1,2,3,4-TETRAHYDRO-ISOQUINOLINE-7-SULFONIC ACID AMIDE
Authors:Martin, J.L., Begun, J., McLeish, M.J., Caine, J.M., Grunewald, G.L.
Deposit date:2000-12-07
Release date:2001-12-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT.
Structure, 9, 2001
1N7I
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THE STRUCTURE OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND THE INHIBITOR LY134046
Descriptor:Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 8,9-DICHLORO-2,3,4,5-TETRAHYDRO-1H-BENZO[C]AZEPINE
Authors:McMillan, F.M., Archbold, J., McLeish, M.J., Caine, J.M., Criscione, K.R., Grunewald, G.L., Martin, J.L.
Deposit date:2002-11-15
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase.
J.Med.Chem., 47, 2004
1N7J
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THE STRUCTURE OF PHENYLETHANOLAMINE N-METHYLTRANSFERASE IN COMPLEX WITH S-ADENOSYLHOMOCYSTEINE AND AN IODINATED INHIBITOR
Descriptor:Phenylethanolamine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 7-IODO-1,2,3,4-TETRAHYDRO-ISOQUINOLINE
Authors:McMillan, F.M., Archbold, J., McLeish, M.J., Caine, J.M., Criscione, K.R., Grunewald, G.L., Martin, J.L.
Deposit date:2002-11-15
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Molecular recognition of sub-micromolar inhibitors by the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase.
J.Med.Chem., 47, 2004
4F37
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STRUCTURE OF THE TETHERED N-TERMINUS OF ALZHEIMER'S DISEASE A PEPTIDE
Descriptor:Colicin-E7 immunity protein, Im7 immunity protein, Fab WO2 anti-amyloid-beta antibody Fab fragment
Authors:Nisbet, R.M., Nuttall, S.D., Caine, J.M., Rober, R., Hittaki, M., Pearce, L.A., Davydova, N., Masters, C.L., Varghese, J.N., Streltsov, V.A.
Deposit date:2012-05-09
Release date:2013-05-15
Last modified:2014-09-03
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-beta peptide.
Proteins, 81, 2013