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2TS1
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STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Descriptor:TYROSYL-TRNA SYNTHETASE
Authors:Brick, P., Bhat, T.N., Blow, D.M.
Deposit date:1989-06-29
Release date:1989-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
J.Mol.Biol., 208, 1989
4TS1
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CRYSTAL STRUCTURE OF A DELETION MUTANT OF A TYROSYL-T/RNA SYNTHETASE COMPLEXED WITH TYROSINE
Descriptor:TYROSYL-tRNA SYNTHETASE, TYROSINE
Authors:Brick, P., Blow, D.M.
Deposit date:1989-06-29
Release date:1989-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a deletion mutant of a tyrosyl-tRNA synthetase complexed with tyrosine.
J.Mol.Biol., 194, 1987
3TS1
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STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE
Descriptor:TYROSYL-TRNA SYNTHETASE, PHOSPHORIC ACID 2-AMINO-3-(4-HYDROXY-PHENYL)-PROPYL ESTER ADENOSIN-5'YL ESTER
Authors:Monteilhet, C., Brick, P., Blow, D.M.
Deposit date:1989-06-29
Release date:1989-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of tyrosyl-tRNA synthetase refined at 2.3 A resolution. Interaction of the enzyme with the tyrosyl adenylate intermediate.
J.Mol.Biol., 208, 1989
1TYC
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STRUCTURAL ANALYSIS OF A SERIES OF MUTANTS OF TYROSYL-TRNA SYNTHETASE: ENHANCEMENT OF CATALYSIS BY HYDROPHOBIC INTERACTIONS
Descriptor:TYROSYL-tRNA SYNTHETASE
Authors:Brown, K.A., Brick, P., De Meester, P., Blow, D.M.
Deposit date:1992-07-06
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Analysis of a Series of Mutants of Tyrosyl-tRNA Synthetase: Enhancement of Catalysis by Hydrophobic Interactions
To be Published
1BA3
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FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM
Descriptor:LUCIFERASE, TRIBROMOMETHANE
Authors:Franks, N.P., Jenkins, A., Conti, E., Lieb, W.R., Brick, P.
Deposit date:1998-04-21
Release date:1998-11-11
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis for the inhibition of firefly luciferase by a general anesthetic.
Biophys.J., 75, 1998
1BA7
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SOYBEAN TRYPSIN INHIBITOR
Descriptor:TRYPSIN INHIBITOR (KUNITZ)
Authors:De Meester, P., Brick, P., Lloyd, L.F., Blow, D.M., Onesti, S.
Deposit date:1998-04-22
Release date:1998-06-17
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the Kunitz-type soybean trypsin inhibitor (STI): implication for the interactions between members of the STI family and tissue-plasminogen activator.
Acta Crystallogr.,Sect.D, 54, 1998
1BBU
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LYSYL-TRNA SYNTHETASE (LYSS) COMPLEXED WITH LYSINE
Descriptor:PROTEIN (LYSYL-TRNA SYNTHETASE), LYSINE
Authors:Onesti, S., Desogus, G., Brevet, A., Chen, J., Plateau, P., Blanquet, S., Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1BBW
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LYSYL-TRNA SYNTHETASE (LYSS)
Descriptor:PROTEIN (LYSYL-TRNA SYNTHETASE)
Authors:Onesti, S., Desogus, G., Brevet, A., Chen, J., Plateau, P., Blanquet, S., Brick, P.
Deposit date:1998-04-24
Release date:2000-11-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural studies of lysyl-tRNA synthetase: conformational changes induced by substrate binding.
Biochemistry, 39, 2000
1LYL
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LYSYL-TRNA SYNTHETASE (LYSU) (E.C.6.1.1.6) COMPLEXED WITH LYSINE
Descriptor:LYSYL-TRNA SYNTHETASE (LYSU), LYSINE
Authors:Onesti, S., Brick, P.
Deposit date:1995-05-03
Release date:1995-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:The crystal structure of the lysyl-tRNA synthetase (LysU) from Escherichia coli
Structure, 3, 1995
1GDH
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CRYSTAL STRUCTURE OF A NAD-DEPENDENT D-GLYCERATE DEHYDROGENASE AT 2.4 ANGSTROMS RESOLUTION
Descriptor:D-GLYCERATE DEHYDROGENASE, SULFATE ION
Authors:Goldberg, J.D., Yoshida, T., Brick, P.
Deposit date:1993-09-22
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Crystal structure of a NAD-dependent D-glycerate dehydrogenase at 2.4 A resolution.
J.Mol.Biol., 236, 1994
1TIE
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CRYSTAL STRUCTURE OF A KUNITZ-TYPE TRYPSIN INHIBITOR FROM ERYTHRINA CAFFRA SEEDS
Descriptor:ERYTHRINA TRYPSIN INHIBITOR
Authors:Onesti, S., Brick, P., Blow, D.M.
Deposit date:1991-02-14
Release date:1992-07-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a Kunitz-type trypsin inhibitor from Erythrina caffra seeds.
J.Mol.Biol., 217, 1991
1A0C
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XYLOSE ISOMERASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES
Descriptor:XYLOSE ISOMERASE, COBALT (II) ION
Authors:Gallay, O., Chopra, R., Conti, E., Brick, P., Blow, D.
Deposit date:1997-11-28
Release date:1998-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
1A0D
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XYLOSE ISOMERASE FROM BACILLUS STEAROTHERMOPHILUS
Descriptor:XYLOSE ISOMERASE, MANGANESE (II) ION
Authors:Gallay, O., Chopra, R., Conti, E., Brick, P., Blow, D.
Deposit date:1997-11-28
Release date:1998-06-03
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
1A0E
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XYLOSE ISOMERASE FROM THERMOTOGA NEAPOLITANA
Descriptor:XYLOSE ISOMERASE, COBALT (II) ION
Authors:Gallay, O., Chopra, R., Conti, E., Brick, P., Blow, D.
Deposit date:1997-11-28
Release date:1998-06-03
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
1AMU
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PHENYLALANINE ACTIVATING DOMAIN OF GRAMICIDIN SYNTHETASE 1 IN A COMPLEX WITH AMP AND PHENYLALANINE
Descriptor:GRAMICIDIN SYNTHETASE 1, MAGNESIUM ION, SULFATE ION, ...
Authors:Conti, E., Stachelhaus, T., Marahiel, M.A., Brick, P.
Deposit date:1997-06-18
Release date:1998-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
EMBO J., 16, 1997
1BCU
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ALPHA-THROMBIN COMPLEXED WITH HIRUGEN AND PROFLAVIN
Descriptor:ALPHA-THROMBIN, HIRUGEN, PROFLAVIN
Authors:Conti, E., Rivetti, C., Wonacott, A., Brick, P.
Deposit date:1998-05-02
Release date:1998-10-14
Last modified:2018-04-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray and spectrophotometric studies of the binding of proflavin to the S1 specificity pocket of human alpha-thrombin.
FEBS Lett., 425, 1998
1BJ5
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HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTIC ACID
Descriptor:HUMAN SERUM ALBUMIN, MYRISTIC ACID
Authors:Curry, S., Mandelkow, H., Brick, P., Franks, N.
Deposit date:1998-07-02
Release date:1998-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites.
Nat.Struct.Biol., 5, 1998
1BKE
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HUMAN SERUM ALBUMIN IN A COMPLEX WITH MYRISTIC ACID AND TRI-IODOBENZOIC ACID
Descriptor:SERUM ALBUMIN, MYRISTIC ACID, 2,3,5-TRIIODOBENZOIC ACID
Authors:Curry, S., Mandelkow, H., Brick, P., Franks, N.
Deposit date:1998-07-06
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Crystal structure of human serum albumin complexed with fatty acid reveals an asymmetric distribution of binding sites.
Nat.Struct.Biol., 5, 1998
1CG2
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CARBOXYPEPTIDASE G2
Descriptor:CARBOXYPEPTIDASE G2, ZINC ION
Authors:Rowsell, S., Pauptit, R.A., Tucker, A.D., Melton, R.G., Blow, D.M., Brick, P.
Deposit date:1996-12-20
Release date:1997-12-24
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy.
Structure, 5, 1997
1COY
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CRYSTAL STRUCTURE OF CHOLESTEROL OXIDASE COMPLEXED WITH A STEROID SUBSTRATE. IMPLICATIONS FOR FAD DEPENDENT ALCOHOL OXIDASES
Descriptor:CHOLESTEROL OXIDASE, 3-BETA-HYDROXY-5-ANDROSTEN-17-ONE, FLAVIN-ADENINE DINUCLEOTIDE
Authors:Li, J., Vrielink, A., Brick, P., Blow, D.M.
Deposit date:1993-06-14
Release date:1993-10-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of cholesterol oxidase complexed with a steroid substrate: implications for flavin adenine dinucleotide dependent alcohol oxidases.
Biochemistry, 32, 1993
1DZF
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RPB5 FROM S.CEREVISIAE
Descriptor:DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1
Authors:Todone, F., Weinzierl, R.O.J., Brick, P., Onesti, S.
Deposit date:2000-02-25
Release date:2000-06-09
Last modified:2014-02-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal Structure of Rpb5, a Universal Eukaryotic RNA Polymerase Subunit and Trascription Factor Interaction Target
Proc.Natl.Acad.Sci.USA, 97, 2000
1E1O
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM, COMPLEXED WITH LYSINE
Descriptor:LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE, LYSINE, ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-09
Release date:2000-07-28
Last modified:2017-03-29
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E1T
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH THE LYSYL_ADENYLATE INTERMEDIATE
Descriptor:LYSYL-TRNA SYNTHETASE, HEAT INDUCIBLE, ADENOSINE-5'-[LYSYL-PHOSPHATE], ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-10
Release date:2000-07-28
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E22
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH LYSINE AND THE NON-HYDROLYSABLE ATP ANALOGUE AMP-PCP
Descriptor:LYSYL-TRNA SYNTHETASE, LYSINE, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-15
Release date:2000-07-28
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
1E24
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LYSYL-TRNA SYNTHETASE (LYSU) HEXAGONAL FORM COMPLEXED WITH LYSINE AND ATP AND MN2+
Descriptor:LYSYL-TRNA SYNTHETASE, LYSINE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Desogus, G., Todone, F., Brick, P., Onesti, S.
Deposit date:2000-05-16
Release date:2000-07-28
Last modified:2011-08-24
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Active Site of Lysyl-tRNA Synthetase: Structural Studies of the Adenylation Reaction
Biochemistry, 39, 2000
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