Author results

1F6R
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CRYSTAL STRUCTURE OF APO-BOVINE ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN
Authors:Chrysina, E.D., Brew, K., Acharya, K.R.
Deposit date:2000-06-23
Release date:2000-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions.
J.Biol.Chem., 275, 2000
1F6S
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CRYSTAL STRUCTURE OF BOVINE ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Chrysina, E.D., Brew, K., Acharya, K.R.
Deposit date:2000-06-23
Release date:2000-12-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structures of apo- and holo-bovine alpha-lactalbumin at 2. 2-A resolution reveal an effect of calcium on inter-lobe interactions.
J.Biol.Chem., 275, 2000
1VZU
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ROLES OF ACTIVE SITE TRYPTOPHANS IN SUBSTRATE BINDING AND CATALYSIS BY ALPHA-1,3 GALACTOSYLTRANSFERASE
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, MANGANESE (II) ION, BETA-LACTOSE, ...
Authors:Zhang, Y., Deshpande, A., Xie, Z., Natesh, R., Acharya, K.R., Brew, K.
Deposit date:2004-05-27
Release date:2004-07-08
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
1VZX
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ROLES OF ACTIVE SITE TRYPTOPHANS IN SUBSTRATE BINDING AND CATALYSIS BY ALPHA-1,3 GALACTOSYLTRANSFERASE
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, BETA-D-GALACTOSE, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Zhang, Y., Deshpande, A., Xie, Z., Natesh, R., Acharya, K.R., Brew, K.
Deposit date:2004-05-28
Release date:2004-07-08
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase.
Glycobiology, 14, 2004
1D2B
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THE MMP-INHIBITORY, N-TERMINAL DOMAIN OF HUMAN TISSUE INHIBITOR OF METALLOPROTEINASES-1 (N-TIMP-1), SOLUTION NMR, 29 STRUCTURES
Descriptor:TISSUE INHIBITOR OF METALLOPROTEINASES-1
Authors:Wu, B., Arumugam, S., Semenchenko, V., Brew, K., Van Doren, S.R.
Deposit date:1999-09-22
Release date:1999-12-22
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:NMR structure of tissue inhibitor of metalloproteinases-1 implicates localized induced fit in recognition of matrix metalloproteinases.
J.Mol.Biol., 295, 2000
1GWV
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - LACTOSE COMPLEX
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Boix, E., Zhang, Y., Swaminathan, G.J., Brew, K., Acharya, K.R.
Deposit date:2002-03-26
Release date:2003-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
1GWW
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - ALPHA-D-GLUCOSE COMPLEX
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Boix, E., Zhang, Y., Swaminathan, G.J., Brew, K., Acharya, K.R.
Deposit date:2002-03-26
Release date:2003-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
1GX0
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - BETA-D-GALACTOSE COMPLEX
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Boix, E., Zhang, Y., Swaminathan, G.J., Brew, K., Acharya, K.R.
Deposit date:2002-03-26
Release date:2003-03-20
Last modified:2011-10-19
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
1GX4
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ALPHA-,1,3 GALACTOSYLTRANSFERASE - N-ACETYL LACTOSAMINE COMPLEX
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Boix, E., Zhang, Y., Swaminathan, G.J., Brew, K., Acharya, K.R.
Deposit date:2002-03-27
Release date:2003-03-27
Last modified:2011-09-07
Method:X-RAY DIFFRACTION (1.46 Å)
Cite:Structural Basis of Ordered Binding of Donor and Acceptor Substrates to the Retaining Glycosyltransferase, Alpha -1,3 Galactosyltransferase
J.Biol.Chem., 277, 2002
1HFZ
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Pike, A.C.W., Brew, K., Acharya, K.R.
Deposit date:1996-06-13
Release date:1997-07-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.
Structure, 4, 1996
1O7O
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ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, MANGANESE (II) ION, BETA-LACTOSE, ...
Authors:Zhang, Y., Swaminathan, G.J., Deshpande, A., Natesh, R., Xie, Z., Acharya, K.R., Brew, K.
Deposit date:2002-11-11
Release date:2003-11-06
Last modified:2018-02-28
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity.
Biochemistry, 42, 2003
1O7Q
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ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, GLYCEROL, MANGANESE (II) ION, ...
Authors:Zhang, Y., Swaminathan, G.J., Deshpande, A., Natesh, R., Xie, Z., Acharya, K.R., Brew, K.
Deposit date:2002-11-12
Release date:2003-11-06
Last modified:2015-04-15
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity.
Biochemistry, 42, 2003
1VZT
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ROLES OF INDIVIDUAL RESIDUES OF ALPHA-1,3 GALACTOSYLTRANSFERASES IN SUBSTRATE BINDING AND CATALYSIS
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Zhang, Y., Swaminathan, G.J., Deshpande, A., Natesh, R., Xie, X., Acharya, K.R., Brew, K.
Deposit date:2004-05-26
Release date:2005-05-26
Last modified:2018-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Roles of Individual Enzyme-Substrate Interactions by Alpha-1,3-Galactosyltransferase in Catalysis and Specificity.
Biochemistry, 42, 2003
1HFX
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Pike, A.C.W., Brew, K., Acharya, K.R.
Deposit date:1996-06-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.
Structure, 4, 1996
1HFY
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ALPHA-LACTALBUMIN
Descriptor:ALPHA-LACTALBUMIN, CALCIUM ION
Authors:Pike, A.C.W., Brew, K., Acharya, K.R.
Deposit date:1996-06-13
Release date:1997-07-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase.
Structure, 4, 1996
1JYD
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CRYSTAL STRUCTURE OF RECOMBINANT HUMAN SERUM RETINOL-BINDING PROTEIN AT 1.7 A RESOLUTION
Descriptor:PLASMA RETINOL-BINDING PROTEIN, GLYCEROL
Authors:Greene, L.H., Chrysina, E.D., Irons, L.I., Papageorgiou, A.C., Acharya, K.R., Brew, K.
Deposit date:2001-09-12
Release date:2003-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Role of conserved residues in structure and stability: Tryptophans of human serum retinol-binding protein, a model for the lipocalin superfamily
Protein Sci., 10, 2001
1JYJ
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CRYSTAL STRUCTURE OF A DOUBLE VARIANT (W67L/W91H) OF RECOMBINANT HUMAN SERUM RETINOL-BINDING PROTEIN AT 2.0 A RESOLUTION
Descriptor:PLASMA RETINOL-BINDING PROTEIN, GLYCEROL
Authors:Greene, L.H., Chrysina, E.D., Irons, L.I., Papageorgiou, A.C., Acharya, K.R., Brew, K.
Deposit date:2001-09-12
Release date:2003-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of Conserved Residues in Structure and Stability: Tryptophans of Human Serum Retinol-Binding Protein, a Model for the Lipocalin Superfamily
Protein Sci., 10, 2001
1K4V
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1.53 A CRYSTAL STRUCTURE OF THE BETA-GALACTOSIDE-ALPHA-1,3-GALACTOSYLTRANSFERASE IN COMPLEX WITH UDP
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Boix, E., Swaminathan, G.J., Zhang, Y., Natesh, R., Brew, K., Acharya, K.R.
Deposit date:2001-10-09
Release date:2002-04-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Structure of UDP complex of UDP-galactose:beta-galactoside-alpha -1,3-galactosyltransferase at 1.53-A resolution reveals a conformational change in the catalytically important C terminus.
J.Biol.Chem., 276, 2001
2J0T
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CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF MMP-1 IN COMPLEX WITH THE INHIBITORY DOMAIN OF TIMP-1
Descriptor:INTERSTITIAL COLLAGENASE, METALLOPROTEINASE INHIBITOR 1, ZINC ION, ...
Authors:Iyer, S., Wei, S., Brew, K., Acharya, K.R.
Deposit date:2006-08-04
Release date:2006-10-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.54 Å)
Cite:Crystal Structure of the Catalytic Domain of Matrix Metalloproteinase-1 in Complex with the Inhibitory Domain of Tissue Inhibitor of Metalloproteinase-1.
J.Biol.Chem., 282, 2007
2JCJ
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CRYSTAL STRUCTURE OF ALPHA-1,3 GALACTOSYLTRANSFERASE (C-TERMINUS TRUNCATED MUTANT-C3) IN COMPLEX WITH UDP AND TRIS
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Jamaluddin, H., Tumbale, P., Withers, S.G., Acharya, K.R., Brew, K.
Deposit date:2006-12-25
Release date:2007-05-22
Method:X-RAY DIFFRACTION (2.02 Å)
Cite:Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis.
J.Mol.Biol., 369, 2007
2JCK
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CRYSTAL STRUCTURE OF ALPHA-1,3 GALACTOSYLTRANSFERASE (R365K) IN COMPLEX WITH UDP AND 2 MANGANESE ION
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION
Authors:Jamaluddin, H., Tumbale, P., Withers, S.G., Acharya, K.R., Brew, K.
Deposit date:2006-12-26
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis.
J.Mol.Biol., 369, 2007
2JCL
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CRYSTAL STRUCTURE OF ALPHA-1,3 GALACTOSYLTRANSFERASE (R365K) IN THE ABSENCE OF LIGANDS
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, SULFATE ION
Authors:Jamaluddin, H., Tumbale, P., Withers, S.G., Acharya, K.R., Brew, K.
Deposit date:2006-12-26
Release date:2007-05-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis.
J.Mol.Biol., 369, 2007
2JCO
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CRYSTAL STRUCTURE OF WILD TYPE ALPHA-1,3 GALACTOSYLTRANSFERASE IN THE ABSENCE OF LIGANDS
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYL TRANSFERASE, GLYCEROL
Authors:Jamaluddin, H., Tumbale, P., Withers, S.G., Acharya, K.R., Brew, K.
Deposit date:2006-12-28
Release date:2007-06-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis.
J.Mol.Biol., 369, 2007
2VFZ
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CRYSTAL STRUCTURE OF ALPHA-1,3 GALACTOSYLTRANSFERASE (R365K) IN COMPLEX WITH UDP-2F-GALACTOSE
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYL TRANSFERASE, URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUOROGALACTOSE, MANGANESE (II) ION
Authors:Jamaluddin, H., Tumbale, P., Withers, S.G., Acharya, K.R., Brew, K.
Deposit date:2007-11-06
Release date:2007-11-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Conformational Changes Induced by Binding Udp-2F-Galactose to Alpha-1,3 Galactosyltransferase-Implications for Catalysis
J.Mol.Biol., 369, 2007
2VS3
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THE BINDING OF UDP-GALACTOSE BY AN ACTIVE SITE MUTANT OF ALPHA-1,3 GALACTOSYLTRANSFERASE (ALPHA3GT)
Descriptor:N-ACETYLLACTOSAMINIDE ALPHA-1,3-GALACTOSYLTRANSFERASE, URIDINE-5'-DIPHOSPHATE, 2-(ACETYLAMINO)-2-DEOXY-4-O-BETA-D-GALACTOPYRANOSYL-ALPHA-D-GLUCOPYRANOSE, ...
Authors:Tumbale, P., Jamaluddin, H., Thiyagarajan, N., Brew, K., Acharya, K.R.
Deposit date:2008-04-18
Release date:2008-07-15
Last modified:2017-07-12
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural Basis of Udp-Galactose Binding by Alpha- 1,3-Galactosyltransferase (Alpha3Gt): Role of Negative Charge on Aspartic Acid 316 in Structure and Activity.
Biochemistry, 47, 2008
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