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2BVX
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DESIGN AND DISCOVERY OF NOVEL, POTENT THROMBIN INHIBITORS WITH A SOLUBILIZING CATIONIC P1-P2-LINKER
Descriptor:ALPHA THROMBIN, HIRUDIN VARIANT-2, N-(5-CHLORO-BENZO[B]THIOPHEN-3-YLMETHYL)-2-[6-CHLORO-OXO-3-(2-PYRIDIN-2-YL-ETHYLAMINO)-2H-PYRAZIN-1-YL]-ACETAMIDE
Authors:Bulat, S., Bosio, S., Grabowski, E., Papadopoulos, M.A., Cerezo-Galvez, S., Rosenbaum, C., Matassa, V.G., Ott, I., Metz, G., Schamberger, J., Sekul, R., Feurer, A.
Deposit date:2005-07-04
Release date:2006-10-25
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing P1-P2-Linker
Lett.Drug Des.Discovery, 3, 2006
2BXT
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DESIGN AND DISCOVERY OF NOVEL, POTENT THROMBIN INHIBITORS WITH A SOLUBILIZING CATIONIC P1-P2-LINKER
Descriptor:ALPHA THROMBIN, HIRUDIN VARIANT-2, 6-CHLORO-1-(2-{[(5-CHLORO-1-BENZOTHIEN-3-YL)METHYL]AMINO}ETHYL)-3-[(2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL
Authors:Bulat, S., Bosio, S., Grabowski, E., Papadopoulos, M.A., Cerezo-Galvez, S., Rosenbaum, C., Matassa, V.G., Ott, I., Metz, G., Schamberger, J., Sekul, R., Feurer, A.
Deposit date:2005-07-27
Release date:2006-10-26
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (1.83 Å)
Cite:Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing P1-P2-Linker
Lett.Drug Des.Discovery, 3, 2006
2BXU
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DESIGN AND DISCOVERY OF NOVEL, POTENT THROMBIN INHIBITORS WITH A SOLUBILIZING CATIONIC P1-P2-LINKER
Descriptor:ALPHA THROMBIN, HIRUDIN, 1-(2-{[(6-AMINO-2-METHYLPYRIDIN-3-YL)METHYL]AMINO}ETHYL)-6-CHLORO-3-[(2,2-DIFLUORO-2-PYRIDIN-2-YLETHYL)AMINO]-1,4-DIHYDROPYRAZIN-2-OL
Authors:Bulat, S., Bosio, S., Grabowski, E., Papadopoulos, M.A., Cerezo-Galvez, S., Rosenbaum, C., Matassa, V.G., Ott, I., Metz, G., Schamberger, J., Sekul, R., Feurer, A.
Deposit date:2005-07-27
Release date:2006-10-26
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Design and Discovery of Novel, Potent Pyrazinone-Based Thrombin Inhibitors with a Solubilizing P1-P2-Linker
Lett.Drug Des.Discovery, 3, 2006
3CJZ
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EFFECTS OF N2,N2-DIMETHYLGUANOSINE ON RNA STRUCTURE AND STABILITY: CRYSTAL STRUCTURE OF AN RNA DUPLEX WITH TANDEM M22G:A PAIRS
Descriptor:RNA (5'-R(*GP*GP*AP*CP*GP*(M2G)P*AP*CP*GP*UP*CP*CP*U)-3')
Authors:Pallan, P.S., Kreutz, C., Bosio, S., Micura, R., Egli, M.
Deposit date:2008-03-14
Release date:2008-10-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs.
Rna, 14, 2008
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