Author results

1IIM
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THYMIDYLYLTRANSFERASE COMPLEXED WITH TTP
Descriptor:glucose-1-phosphate thymidylyltransferase, THYMIDINE-5'-TRIPHOSPHATE
Authors:Barton, W.A., Lesniak, J., Biggins, J.B., Jeffrey, P.D., Jiang, J., Rajashankar, K.R., Thorson, J.S., Nikolov, D.B.
Deposit date:2001-04-23
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
1IIN
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THYMIDYLYLTRANSFERASE COMPLEXED WITH UDP-GLUCOSE
Descriptor:glucose-1-phosphate thymidylyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Barton, W.A., Lesniak, J., Biggins, J.B., Jeffrey, P.D., Jiang, J., Rajashankar, K.R., Thorson, J.S., Nikolov, D.B.
Deposit date:2001-04-23
Release date:2001-05-09
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization.
Nat.Struct.Biol., 8, 2001
1MP3
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L89T VARIANT OF S. ENTERICA RMLA
Descriptor:GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE, THYMIDINE-5'-TRIPHOSPHATE
Authors:Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.T., Nikolov, D.B.
Deposit date:2002-09-11
Release date:2002-10-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1MP4
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W224H VARIANT OF S. ENTERICA RMLA
Descriptor:W224H Variant of S. Enterica RmlA Bound to UDP-Glucose, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.S., Nikolov, D.B.
Deposit date:2002-09-11
Release date:2002-10-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
1MP5
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Y177F VARIANT OF S. ENTERICA RMLA
Descriptor:Y177F VARIANT OF S. ENTERICA RmlA BOUND TO UDP-GLUCOSE, URIDINE-5'-DIPHOSPHATE-GLUCOSE
Authors:Barton, W.A., Biggins, J.B., Jiang, J., Thorson, J.S., Nikolov, D.B.
Deposit date:2002-09-11
Release date:2002-10-09
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Expanding pyrimidine diphosphosugar libraries via structure-based nucleotidylyltransferase engineering
Proc.Natl.Acad.Sci.USA, 99, 2002
6CCE
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CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH INHIBITOR KANGLEMYCIN A
Descriptor:RNA polymerase-binding protein RbpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M., Darst, S.A., Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6CCV
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CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS RNA POLYMERASE TRANSCRIPTION INITIATION COMPLEX WITH INHIBITOR RIFAMPICIN
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Lilic, M., Darst, S.A., Campbell, E.A.
Deposit date:2018-02-07
Release date:2018-08-15
Last modified:2019-02-27
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
6DCF
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CRYSTAL STRUCTURE OF A MYCOBACTERIUM SMEGMATIS TRANSCRIPTION INITIATION COMPLEX WITH RIFAMPICIN-RESISTANT RNA POLYMERASE AND BOUND TO KANGLEMYCIN A
Descriptor:RNA polymerase-binding protein RbpA, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
Authors:Lilic, M., Darst, S.A., Campbell, E.A.
Deposit date:2018-05-06
Release date:2018-09-05
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (3.45 Å)
Cite:Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism.
Nat Commun, 9, 2018
1ZXF
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SOLUTION STRUCTURE OF A SELF-SACRIFICING RESISTANCE PROTEIN, CALC FROM MICROMONOSPORA ECHINOSPORA
Descriptor:CalC
Authors:Singh, S., Hager, M.H., Zhang, C., Griffith, B.R., Lee, M.S., Hallenga, K., Markley, J.L., Thorson, J.S., Center for Eukaryotic Structural Genomics (CESG)
Deposit date:2005-06-08
Release date:2005-12-13
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structural insight into the self-sacrifice mechanism of enediyne resistance.
Acs Chem.Biol., 1, 2006