Author results

3ME9
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CRYSTAL STRUCTURE OF SGF29 IN COMPLEX WITH H3K4ME3 PEPTIDE
Descriptor:SAGA-associated factor 29 homolog, Histone H3, UNKNOWN ATOM OR ION, ...
Authors:Bian, C., Tempel, W., Xu, C., Guo, Y., Dong, A., Crombet, L., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.37 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
3MEA
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CRYSTAL STRUCTURE OF THE SGF29 IN COMPLEX WITH H3K4ME3
Descriptor:SAGA-associated factor 29 homolog, Histone H3
Authors:Bian, C., Xu, C., Tempel, W., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-03-31
Release date:2010-04-28
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.26 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
4II1
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CRYSTAL STRUCTURE OF THE ZINC FINGER OF ZGPAT
Descriptor:Zinc finger CCCH-type with G patch domain-containing protein, ZINC ION, UNKNOWN ATOM OR ION
Authors:Bian, C., Tempel, W., Dong, A., Chao, X., Fu, M., Wernimont, A.K., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-12-19
Release date:2013-02-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Crystal structure of the zinc finger of ZGPAT
to be published
3IUF
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CRYSTAL STRUCTURE OF THE C2H2-TYPE ZINC FINGER DOMAIN OF HUMAN UBI-D4
Descriptor:Zinc finger protein ubi-d4, ZINC ION
Authors:Tempel, W., Xu, C., Bian, C., Adams-Cioaba, M., Eryilmaz, J., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2009-08-31
Release date:2009-11-03
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the Cys2His2-type zinc finger domain of human DPF2.
Biochem.Biophys.Res.Commun., 413, 2011
3QIR
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CRYSTAL STRUCTURE OF PIWIL2 PAZ DOMAIN
Descriptor:Piwi-like protein 2
Authors:Dong, A., Xu, C., Bian, C., Wernimont, A.K., Kania, J., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-01-27
Release date:2011-02-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of PIWIL2 PAZ domain
To be Published
3QMG
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NON-METHYLATED CPG ISLANDS BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*AP*CP*GP*GP*TP*GP*GP*C)-3', 5'-D(*GP*CP*CP*AP*CP*CP*GP*TP*TP*GP*GP*C)-3', ...
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMH
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NON-METHYLATED CPG ISLANDS (DNA-TCGA) BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*TP*CP*GP*AP*TP*GP*GP*C)-3', ZINC ION
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3QMI
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STRUCTURAL BASIS OF SELECTIVE BINDING OF NON-METHYLATED CPG ISLANDS (DNA-ACGT) BY THE CXXC DOMAIN OF CFP1
Descriptor:CpG-binding protein, 5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3', ZINC ION, ...
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-02-04
Release date:2011-02-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
3RCO
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CRYSTAL STRUCTURE OF A CONSERVED MOTIF IN HUMAN TDRD7
Descriptor:Tudor domain-containing protein 7, CHLORIDE ION
Authors:Dong, A., Xu, C., Walker, J.R., Lam, R., Guo, Y., Bian, C., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-03-31
Release date:2012-04-04
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of a conserved motif in human TDRD7
To be Published
3UZD
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CRYSTAL STRUCTURE OF 14-3-3 GAMMA
Descriptor:14-3-3 protein gamma, Histone deacetylase 4, NITRATE ION, ...
Authors:Xu, C., Bian, C., MacKenzie, F., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-07
Release date:2012-03-21
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
4HP1
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CRYSTAL STRUCTURE OF TET3 IN COMPLEX WITH A NON-CPG DSDNA
Descriptor:DNA (5'-D(*GP*CP*CP*AP*CP*(5CM)P*GP*GP*TP*GP*GP*C)-3'), LOC100036628 protein, ZINC ION
Authors:Chao, X., Tempel, W., Bian, C., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-10-23
Release date:2012-12-05
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
4HP3
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CRYSTAL STRUCTURE OF TET3 IN COMPLEX WITH A CPG DSDNA
Descriptor:DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*TP*TP*GP*GP*C)-3'), LOC100036628 protein, UNKNOWN ATOM OR ION, ...
Authors:Chao, X., Tempel, W., Bian, C., Bountra, C., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2012-10-23
Release date:2012-12-05
Last modified:2012-12-19
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development.
Cell(Cambridge,Mass.), 151, 2012
2FA9
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THE CRYSTAL STRUCTURE OF SAR1[H79G]-GDP PROVIDES INSIGHT INTO THE COAT-CONTROLLED GTP HYDROLYSIS IN THE DISASSEMBLY OF COP II
Descriptor:GTP-binding protein SAR1b, MAGNESIUM ION, SULFATE ION, ...
Authors:Rao, Y., Huang, M., Yuan, C., Bian, C., Hou, X.
Deposit date:2005-12-07
Release date:2006-09-05
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of Sar1[H79G]-GDP Which Provides Insight into the Coat-controlled GTP Hydrolysis in the Disassembly of COP II
Chin.J.Struct.Chem., 25, 2006
2FMX
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AN OPEN CONFORMATION OF SWITCH I REVEALED BY SAR1-GDP CRYSTAL STRUCTURE AT LOW MG(2+)
Descriptor:GTP-binding protein SAR1b, SULFATE ION, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:Rao, Y., Bian, C., Yuan, C., Li, Y., Huang, M.
Deposit date:2006-01-10
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:An open conformation of switch I revealed by Sar1-GDP crystal structure at low Mg(2+)
Biochem.Biophys.Res.Commun., 348, 2006
3S8S
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CRYSTAL STRUCTURE OF THE RRM DOMAIN OF HUMAN SETD1A
Descriptor:Histone-lysine N-methyltransferase SETD1A, UNKNOWN ATOM OR ION
Authors:Chao, X., Tempel, W., Bian, C., Cerovina, T., Walker, J.R., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-05-30
Release date:2011-06-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of the RRM domain of human SETD1A
to be published
3S93
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CRYSTAL STRUCTURE OF CONSERVED MOTIF IN TDRD5
Descriptor:Tudor domain-containing protein 5, UNKNOWN ATOM OR ION
Authors:Chao, X., Tempel, W., Bian, C., Kania, J., Wernimont, A.K., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-05-31
Release date:2011-08-31
Method:X-RAY DIFFRACTION (2.28 Å)
Cite:Crystal structure of conserved motif in TDRD5
to be published
3U1U
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CRYSTAL STRUCTURE OF RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG PLUS-3 DOMAIN
Descriptor:RNA polymerase-associated protein RTF1 homolog, SULFATE ION, GLYCEROL, ...
Authors:Guo, Y., Tempel, W., Bian, C., Wernimont, A.K., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-09-30
Release date:2012-04-04
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of RNA polymerase-associated protein RTF1 homolog Plus-3 domain
to be published
3UXG
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CRYSTAL STRUCTURE OF RFXANK
Descriptor:DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION
Authors:Tempel, W., Chao, X., Bian, C., Li, Y., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-12-05
Release date:2012-06-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
6C1Y
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MBD OF HUMAN MECP2 IN COMPLEX WITH METHYLATED DNA
Descriptor:Methyl-CpG-binding protein 2, 12-mer DNA, UNKNOWN ATOM OR ION
Authors:Liu, K., Bian, C., Tempel, W., Wernimont, A.K., Arrowsmith, C.H., Bountra, C., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2018-01-05
Release date:2018-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:mbd of human mecp2 in complex with methylated DNA
to be published
3Q1J
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CRYSTAL STRUCTURE OF TUDOR DOMAIN 1 OF HUMAN PHD FINGER PROTEIN 20
Descriptor:PHD finger protein 20, UNKNOWN ATOM OR ION
Authors:Tempel, W., Li, Z., Wernimont, A.K., Chao, X., Bian, C., Lam, R., Crombet, L., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2010-12-17
Release date:2011-02-09
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins.
Febs Lett., 586, 2012
3QII
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CRYSTAL STRUCTURE OF TUDOR DOMAIN 2 OF HUMAN PHD FINGER PROTEIN 20
Descriptor:PHD finger protein 20, UNKNOWN ATOM OR ION
Authors:Li, Z., Tempel, W., Wernimont, A.K., Chao, X., Bian, C., Lam, R., Crombet, L., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Structural Genomics Consortium (SGC)
Deposit date:2011-01-27
Release date:2011-02-09
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structures of the Tudor domains of human PHF20 reveal novel structural variations on the Royal Family of proteins.
Febs Lett., 586, 2012
2I2Z
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HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTATE AND ASPIRIN
Descriptor:Serum albumin, MYRISTIC ACID, 2-HYDROXYBENZOIC ACID
Authors:Yang, F., Bian, C., Zhu, L., Zhao, G., Huang, Z., Huang, M.
Deposit date:2006-08-17
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin
J.Struct.Biol., 157, 2007
2I30
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HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTATE AND SALICYLIC ACID
Descriptor:Serum albumin, 2-HYDROXYBENZOIC ACID, MYRISTIC ACID
Authors:Yang, F., Bian, C., Zhu, L., Zhao, G., Huang, Z., Huang, M.
Deposit date:2006-08-17
Release date:2006-12-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Effect of human serum albumin on drug metabolism: Structural evidence of esterase activity of human serum albumin
J.Struct.Biol., 157, 2007
3CX9
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CRYSTAL STRUCTURE OF HUMAN SERUM ALBUMIN COMPLEXED WITH MYRISTIC ACID AND LYSOPHOSPHATIDYLETHANOLAMINE
Descriptor:Serum albumin, MYRISTIC ACID, (2S)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-hydroxypropyl hexadecanoate
Authors:Guo, S., Yang, F., Chen, L., Bian, C., Huang, M.
Deposit date:2008-04-24
Release date:2009-04-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis of transport of lysophospholipids by human serum albumin.
Biochem.J., 423, 2009
3LX7
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CRYSTAL STRUCTURE OF A NOVEL TUDOR DOMAIN-CONTAINING PROTEIN SGF29
Descriptor:SAGA-associated factor 29 homolog, SULFATE ION, UNKNOWN ATOM OR ION
Authors:Bian, C.B., Xu, C., Tempel, W., Lam, R., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A.M., Bochkarev, A., Min, J.
Deposit date:2010-02-24
Release date:2010-05-05
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.
Embo J., 30, 2011
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