6NUI | | HUMAN GUANYLATE KINASE | | Descriptor: | Guanylate kinase | | Authors: | Sabo, T.M., Khan, N., Ban, D., Trigo-Mourino, P., Carneiro, M.G., Trent, J.O., Konrad, M., Lee, D. | | Deposit date: | 2019-02-01 | | Release date: | 2019-06-26 | | Last modified: | 2019-08-14 | | Method: | SOLUTION NMR | | Cite: | Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer.
J.Biol.Chem., 294, 2019
|
|
4UN2 | | CRYSTAL STRUCTURE OF THE UBA DOMAIN OF DSK2 IN COMPLEX WITH UBIQUITIN | | Descriptor: | UBIQUITIN, UBIQUITIN DOMAIN-CONTAINING PROTEIN DSK2 | | Authors: | Michielssens, S., Peters, J.H., Ban, D., Pratihar, S., Seeliger, D., Sharma, M., Giller, K., Sabo, T.M., Becker, S., Lee, D., Griesinger, C., de Groot, B.L. | | Deposit date: | 2014-05-23 | | Release date: | 2014-08-27 | | Last modified: | 2014-09-24 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | A Designed Conformational Shift to Control Protein Binding Specificity.
Angew.Chem.Int.Ed.Engl., 53, 2014
|
|
2MWH | | NMR SOLUTION STRUCTURE OF LIGAND-FREE OAA | | Descriptor: | Anti-HIV lectin OAA | | Authors: | Lee, D., Carneiro, M.G., Koharudin, L.M., Griesinger, C., Gronenborn, A.M., Ban, D., Sabo, T., Trigo-Mourino, P., Mazur, A. | | Deposit date: | 2014-11-10 | | Release date: | 2015-04-22 | | Last modified: | 2015-06-10 | | Method: | SOLUTION NMR | | Cite: | Sampling of Glycan-Bound Conformers by the Anti-HIV Lectin Oscillatoria agardhii agglutinin in the Absence of Sugar.
Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
2MWY | | MDMX-P53 | | Descriptor: | Protein Mdm4, Cellular tumor antigen p53 | | Authors: | Grace, C.R. | | Deposit date: | 2014-12-03 | | Release date: | 2016-01-27 | | Last modified: | 2016-05-11 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
|
|
2N06 | | MDMX-298 | | Descriptor: | Protein Mdm4, 4-[[(4S,5R)-5-(4-chlorophenyl)-4-(3-methoxyphenyl)-2-(4-methoxy-2-propan-2-yloxy-phenyl)-4,5-dihydroimidazol-1-yl]carbonyl]piperazin-2-one | | Authors: | Grace, C.R., Kriwacki, R.W. | | Deposit date: | 2015-03-04 | | Release date: | 2016-01-27 | | Last modified: | 2019-11-06 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
|
|
2N0U | | MDMX-057 | | Descriptor: | Protein Mdm4, 4-[(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-1-(3-oxidanylidenepiperazin-1-yl)carbonyl-4,5-dihydroimidazol-2-yl]-3-propan-2-yloxy-benzenecarbonitrile | | Authors: | Grace, C.R., Kriwacki, R.W. | | Deposit date: | 2015-03-17 | | Release date: | 2016-01-27 | | Last modified: | 2016-05-04 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
|
|
2N0W | | MDMX-SJ212 | | Descriptor: | Protein Mdm4, 4-({(4S,5R)-4-(5-bromo-2-fluorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one | | Authors: | Grace, C.R., Kriwacki, R.W. | | Deposit date: | 2015-03-17 | | Release date: | 2016-01-27 | | Last modified: | 2016-05-04 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
|
|
2N14 | | MDMX-295 | | Descriptor: | Protein Mdm4, 4-({(4S,5R)-4-(3-chlorophenyl)-5-(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one | | Authors: | Grace, C.R., Kriwacki, R.W. | | Deposit date: | 2015-03-20 | | Release date: | 2016-01-27 | | Last modified: | 2016-05-04 | | Method: | SOLUTION NMR | | Cite: | Monitoring Ligand-Induced Protein Ordering in Drug Discovery.
J.Mol.Biol., 428, 2016
|
|
