Author results

4NBI
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D-AMINOACYL-TRNA DEACYLASE (DTD) FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH D-TYROSYL-3'-AMINOADENOSINE AT 1.86 ANGSTROM RESOLUTION
Descriptor:D-tyrosyl-tRNA(Tyr) deacylase, 3'-deoxy-3'-(D-tyrosylamino)adenosine, TRIETHYLENE GLYCOL
Authors:Ahmad, S., Routh, S.B., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2013-10-23
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Mechanism of chiral proofreading during translation of the genetic code.
Elife, 2, 2013
4NBJ
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D-AMINOACYL-TRNA DEACYLASE (DTD) FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH D-TYROSYL-3'-AMINOADENOSINE AT 2.20 ANGSTROM RESOLUTION
Descriptor:D-tyrosyl-tRNA(Tyr) deacylase, 3'-deoxy-3'-(D-tyrosylamino)adenosine
Authors:Ahmad, S., Routh, S.B., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2013-10-23
Release date:2013-12-18
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Mechanism of chiral proofreading during translation of the genetic code.
Elife, 2, 2013
4RR6
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 1)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RR7
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 2)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RR8
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 3)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RR9
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA (SNAPSHOT 4)
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRA
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 1)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRB
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 2)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRC
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 3)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRD
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N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA (SNAPSHOT 4)
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRF
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EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM METHANOCOCCUS JANNASCHII WITH L-SER3AA
Descriptor:Threonine--tRNA ligase, SERINE-3'-AMINOADENOSINE, CHLORIDE ION, ...
Authors:Ahmad, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRG
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EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM METHANOCOCCUS JANNASCHII WITH L-THR3AA
Descriptor:Threonine--tRNA ligase, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Ahmad, S., Yerabham, A.S.K., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRH
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K116M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRI
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K116M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRJ
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Y115A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRK
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Y115A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRL
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E129A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-SER3AA
Descriptor:Probable threonine--tRNA ligase 2, SERINE-3'-AMINOADENOSINE
Authors:Ahmad, S., Yerabham, A.S.K., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.965 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRM
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E129A MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM AEROPYRUM PERNIX WITH L-THR3AA
Descriptor:Probable threonine--tRNA ligase 2, 3'-deoxy-3'-(L-threonylamino)adenosine, MAGNESIUM ION, ...
Authors:Ahmad, S., Muthukumar, S., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
5EYL
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TUBULIN-BINDING DARPIN
Descriptor:DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), PHOSPHATE ION, GLYCEROL
Authors:Ahmad, S., Kossow, M., Gigant, B.
Deposit date:2015-11-25
Release date:2016-07-20
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin.
Sci Rep, 6, 2016
5EYP
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TUBULIN-DARPIN COMPLEX
Descriptor:Tubulin alpha chain, Tubulin beta chain, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), ...
Authors:Ahmad, S., Knossow, M., Gigant, B.
Deposit date:2015-11-25
Release date:2016-07-20
Last modified:2017-09-06
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin.
Sci Rep, 6, 2016
5J61
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D-AMINOACYL-TRNA DEACYLASE (DTD) FROM PLASMODIUM FALCIPARUM IN COMPLEX WITH GLYCYL-3'-AMINOADENOSINE AT 2.10 ANGSTROM RESOLUTION
Descriptor:D-tyrosyl-tRNA(Tyr) deacylase, 3'-deoxy-3'-(glycylamino)adenosine
Authors:Routh, S.B., Ahmad, S., Sankaranarayanan, R.
Deposit date:2016-04-04
Release date:2016-09-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Elongation Factor Tu Prevents Misediting of Gly-tRNA(Gly) Caused by the Design Behind the Chiral Proofreading Site of D-Aminoacyl-tRNA Deacylase
Plos Biol., 14, 2016
5HV9
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HUMAN LTC4S MUTANT-S36E
Descriptor:Leukotriene C4 synthase, GLUTATHIONE, SULFATE ION
Authors:Thulasingam, M., Ahmad, H.R.S., Rinaldo-Matthis, A., Haeggstrom, J.Z.
Deposit date:2016-01-28
Release date:2016-07-13
Last modified:2017-09-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phosphorylation of Leukotriene C4 Synthase at Serine 36 Impairs Catalytic Activity.
J.Biol.Chem., 291, 2016
4RRQ
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K121M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI WITH L-SER3AA
Descriptor:Threonine--tRNA ligase, SERINE-3'-AMINOADENOSINE
Authors:Hussain, T., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
4RRR
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K121M MUTANT OF N-TERMINAL EDITING DOMAIN OF THREONYL-TRNA SYNTHETASE FROM PYROCOCCUS ABYSSI WITH L-THR3AA
Descriptor:Threonine--tRNA ligase, 3'-deoxy-3'-(L-threonylamino)adenosine
Authors:Hussain, T., Kamarthapu, V., Sankaranarayanan, R.
Deposit date:2014-11-06
Release date:2015-07-15
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
Nat Commun, 6, 2015
3D2A
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STRUCTURE OF 1-17A4, A THERMOSTABLE MUTANT OF BACILLUS SUBTILIS LIPASE OBTAINED THROUGH DIRECTED EVOLUTION
Descriptor:Lipase
Authors:Sankaranarayanan, R., Kamal, M.Z.
Deposit date:2008-05-08
Release date:2008-06-03
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Thermostable Bacillus subtilis lipases: in vitro evolution and structural insight
J.Mol.Biol., 381, 2008
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