Author results

5FDB
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IRON FREE RAT CYSTEINE DIOXYGENASE R60QC164R VARIANT
Descriptor:Cysteine dioxygenase type 1
Authors:Fellner, M., Davies, C.G., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2015-12-16
Release date:2016-12-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Iron free rat cysteine dioxygenase R60QC164R variant
To be published
5EZW
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THIOSULFATE BOUND RAT CYSTEINE DIOXYGENASE Y157H VARIANT
Descriptor:Cysteine dioxygenase type 1, FE (II) ION, THIOSULFATE
Authors:Fellner, M., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2015-11-27
Release date:2016-11-09
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Thiosulfate bound rat cysteine dioxygenase Y157H variant
To be published
5EXQ
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HUMAN CYTOCHROME C Y48H
Descriptor:Cytochrome c, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
Authors:Fellner, M., Jameson, G.N.L., Ledgerwood, E.C., Wilbanks, S.M.
Deposit date:2015-11-24
Release date:2016-11-30
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:To be announced
To be published
5ESI
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SACCHAROMYCES CEREVISIAE CYP51 (LANOSTEROL 14-ALPHA DEMETHYLASE) G73W MUTANT
Descriptor:Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Sagatova, A., Keniya, M.V., Wilson, R., Sabherwal, M., Tyndall, J.D.A., Monk, B.C.
Deposit date:2015-11-16
Release date:2016-11-23
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structures of lanosterol 14-alpha demethylase mutants.
To Be Published
5EFU
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RESTING STATE OF RAT CYSTEINE DIOXYGENASE H155Q VARIANT
Descriptor:Cysteine dioxygenase type 1, FE (II) ION
Authors:Fellner, M., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2015-10-26
Release date:2016-10-26
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Resting state of rat cysteine dioxygenase H155Q variant
To be published
4Z82
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CYSTEINE BOUND RAT CYSTEINE DIOXYGENASE C164S VARIANT AT PH 8.1
Descriptor:Cysteine dioxygenase type 1, FE (II) ION, CYSTEINE
Authors:Fellner, M., Tchesnokov, E.P., Siakkou, E., Rutledge, M.T., Kanitz, M., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2015-04-08
Release date:2016-06-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Influence of cysteine 164 on active site structure in rat cysteine dioxygenase.
J.Biol.Inorg.Chem., 21, 2016
4YYO
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RESTING STATE OF RAT CYSTEINE DIOXYGENASE C164S VARIANT
Descriptor:Cysteine dioxygenase type 1, FE (II) ION, CHLORIDE ION
Authors:Fellner, M., Tchesnokov, E.P., Siakkou, E., Rutledge, M.T., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2015-03-24
Release date:2016-06-01
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.77 Å)
Cite:Influence of cysteine 164 on active site structure in rat cysteine dioxygenase.
J.Biol.Inorg.Chem., 21, 2016
4YSF
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RESTING STATE OF RAT CYSTEINE DIOXYGENASE H155N VARIANT
Descriptor:Cysteine dioxygenase type 1, FE (II) ION
Authors:Fellner, M., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2015-03-17
Release date:2016-07-20
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Resting state of rat cysteine dioxygenase H155N variant
To be published
4YNI
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IRON FREE SUCCINATE BOUND RAT CYSTEINE DIOXYGENASE
Descriptor:Cysteine dioxygenase type 1, SODIUM ION, SUCCINIC ACID
Authors:Fellner, M., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2015-03-10
Release date:2016-03-23
Method:X-RAY DIFFRACTION (2.404 Å)
Cite:Iron free succinate bound rat cysteine dioxygenase
To be published
4WVZ
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CRYSTAL STRUCTURE OF ARTIFICIAL CROSSLINKED THIOL DIOXYGENASE G95C VARIANT FROM PSEUDOMONAS AERUGINOSA
Descriptor:Thiol dioxygenase, FE (II) ION
Authors:FELLNER, M., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2014-11-09
Release date:2016-02-24
Last modified:2016-03-23
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Substrate and pH-Dependent Kinetic Profile of 3-Mercaptopropionate Dioxygenase from Pseudomonas aeruginosa.
Biochemistry, 55, 2016
4WMZ
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S. CEREVISIAE CYP51 COMPLEXED WITH FLUCONAZOLE IN THE ACTIVE SITE
Descriptor:Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE, 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL
Authors:Sagatova, A., Keniya, M.V., Wilson, R., Wilbanks, S.M., Monk, B.C., Tyndall, J.D.A.
Deposit date:2014-10-09
Release date:2015-07-01
Last modified:2017-09-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Insights into Binding of the Antifungal Drug Fluconazole to Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase.
Antimicrob.Agents Chemother., 59, 2015
4UBH
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RESTING STATE OF RAT CYSTEINE DIOXYGENASE Y157F VARIANT
Descriptor:Cysteine dioxygenase type 1, FE (II) ION, SODIUM ION, ...
Authors:Tchesnokov, E.P., Fellner, M., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2014-08-13
Release date:2015-02-11
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystal structure of cysteine dioxygenase mutant
To be published
4UBG
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RESTING STATE OF RAT CYSTEINE DIOXYGENASE C93G VARIANT
Descriptor:Cysteine dioxygenase type 1, FE (II) ION, SODIUM ION
Authors:Fellner, M., Tchesnokov, E.P., Jameson, G.N., Wilbanks, S.M.
Deposit date:2014-08-13
Release date:2014-11-26
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The Cys-Tyr Cross-Link of Cysteine Dioxygenase Changes the Optimal pH of the Reaction without a Structural Change.
Biochemistry, 53, 2014
4TLF
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CRYSTAL STRUCTURE OF THIOL DIOXYGENASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Thiol dioxygenase, FE (II) ION
Authors:FELLNER, M., Tchesnokov, E.P., Jameson, G.N.L., Wilbanks, S.M.
Deposit date:2014-05-29
Release date:2015-06-17
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (2.137 Å)
Cite:The Cysteine Dioxygenase Homologue from Pseudomonas aeruginosa Is a 3-Mercaptopropionate Dioxygenase.
J.Biol.Chem., 290, 2015
4OYQ
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(6-ISOTHIOCYANATOHEXYL)BENZENE INHIBITOR COMPLEXED WITH MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, 6-isothiocyanatohexylbenzene, SULFATE ION, ...
Authors:Spencer, E.S., Dale, E.J., Gommans, A.L., Vo, C.T., Rutledge, M.T., Nakatani, Y., Gamble, A.B., Smith, R.A.J., Wilbanks, S.M., Hampton, M.B., Tyndall, J.D.A.
Deposit date:2014-02-12
Release date:2014-03-05
Last modified:2014-08-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:To be published
To be published
4OSF
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4-(2-ISOTHIOCYANATOETHYL)PHENOL INHIBITOR COMPLEXED WITH MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, N-[2-(4-hydroxyphenyl)ethyl]thioformamide, SULFATE ION, ...
Authors:Spencer, E.S., Dale, E.J., Gommans, A.L., Vo, C.T., Rutledge, M.T., Nakatani, Y., Gamble, A.B., Smith, R.A.J., Wilbanks, S.M., Hampton, M.B., Tyndall, J.D.A.
Deposit date:2014-02-12
Release date:2014-03-12
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor
Eur.J.Med.Chem., 93, 2015
4KWL
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RAT CYSTEINE DIOXYGENASE WITH 3-MERCAPTOPROPIONIC ACID PERSULFIDE BOUND
Descriptor:Cysteine dioxygenase type 1, FE (II) ION, 3-disulfanylpropanoic acid
Authors:Souness, R.J., Wilbanks, S.M., Jameson, G.B., Jameson, G.N.L.
Deposit date:2013-05-24
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Mechanistic implications of persulfenate and persulfide binding in the active site of cysteine dioxygenase.
Biochemistry, 52, 2013
4KWK
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RAT CYSTEINE DIOXYGENASE WITH CYSTEINE PERSULFIDE BOUND TO ACTIVE SITE IRON
Descriptor:Cysteine dioxygenase type 1, FE (II) ION, S-MERCAPTOCYSTEINE
Authors:Souness, R.J., Wilbanks, S.M., Jameson, G.B., Jameson, G.N.L.
Deposit date:2013-05-24
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanistic implications of persulfenate and persulfide binding in the active site of cysteine dioxygenase.
Biochemistry, 52, 2013
4KWJ
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RESTING STATE OF RAT CYSTEINE DIOXYGENASE
Descriptor:Cysteine dioxygenase type 1, FE (II) ION
Authors:Souness, R.J., Wilbanks, S.M., Jameson, G.B., Jameson, G.N.L.
Deposit date:2013-05-24
Release date:2013-10-23
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mechanistic implications of persulfenate and persulfide binding in the active site of cysteine dioxygenase.
Biochemistry, 52, 2013
4KQ6
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PRODUCT COMPLEX OF LUMAZINE SYNTHASE FROM CANDIDA GLABRATA
Descriptor:6,7-dimethyl-8-ribityllumazine synthase, SULFATE ION, 1-deoxy-1-(6,7-dimethyl-2,4-dioxo-3,4-dihydropteridin-8(2H)-yl)-D-ribitol, ...
Authors:Shankar, M., Wilbanks, S.M., Nakatani, Y., Monk, B.C., Tyndall, J.D.A.
Deposit date:2013-05-14
Release date:2013-05-29
Last modified:2013-08-28
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Catalysis product captured in lumazine synthase from the fungal pathogen Candida glabrata.
Acta Crystallogr.,Sect.D, 69, 2013
4F2K
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MACROPHAGE MIGRATION INHIBITORY FACTOR COVALENTLY COMPLEXED WITH PHENETHYLISOTHIOCYANATE
Descriptor:Macrophage migration inhibitory factor, N-(2-phenylethyl)thioformamide, SULFATE ION, ...
Authors:Tyndall, J.D.A., Bernhagen, J., Hampton, M.B., Wilbanks, S.M., Rutledge, M.T.
Deposit date:2012-05-08
Release date:2012-06-06
Last modified:2012-12-26
Method:X-RAY DIFFRACTION (1.53 Å)
Cite:Macrophage migration inhibitory factor covalently complexed with phenethyl isothiocyanate
Acta Crystallogr.,Sect.F, 68, 2012
3WNT
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MULTIPLE BINDING MODES OF BENZYL ISOTHIOCYANATE INHIBITOR COMPLEXED WITH MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, N-benzylthioformamide, SULFATE ION, ...
Authors:Spencer, E.S., Dale, E.J., Gommans, A.L., Rutledge, M.T., Gamble, A.B., Smith, R.A.J., Wilbanks, S.M., Hampton, M.B., Tyndall, J.D.A.
Deposit date:2013-12-16
Release date:2014-03-05
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.074 Å)
Cite:Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor
Eur.J.Med.Chem., 93, 2015
3WNS
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ALLYL ISOTHIOCYANATE INHIBITOR COMPLEXED WITH MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, N-prop-2-en-1-ylthioformamide, SULFATE ION, ...
Authors:Spencer, E.S., Dale, E.J., Gommans, A.L., Rutledge, M.T., Gamble, A.B., Smith, R.A.J., Wilbanks, S.M., Hampton, M.B., Tyndall, J.D.A.
Deposit date:2013-12-16
Release date:2014-03-05
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (1.658 Å)
Cite:Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor
Eur.J.Med.Chem., 93, 2015
3WNR
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MULTIPLE BINDING MODES OF BENZYL ISOTHIOCYANATE INHIBITOR COMPLEXED WITH MACROPHAGE MIGRATION INHIBITORY FACTOR
Descriptor:Macrophage migration inhibitory factor, N-benzylthioformamide, SULFATE ION, ...
Authors:Spencer, E.S., Dale, E.J., Gommans, A.L., Rutledge, M.T., Gamble, A.B., Smith, R.A.J., Wilbanks, S.M., Hampton, M.B., Tyndall, J.D.A.
Deposit date:2013-12-16
Release date:2014-03-05
Last modified:2015-04-01
Method:X-RAY DIFFRACTION (2.008 Å)
Cite:Multiple binding modes of isothiocyanates that inhibit macrophage migration inhibitory factor
Eur.J.Med.Chem., 93, 2015
3USS
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CRYSTAL STRUCTURE OF CYSTEINE DIOXYGENASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Putative uncharacterized protein, FE (II) ION, SULFATE ION, ...
Authors:Wilbanks, S.M., Tchesnokov, E.P., Jameson, G.N.L.
Deposit date:2011-11-23
Release date:2012-01-18
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Crystal Structure, Kinetics and M ssbauer Spectroscopic Studies of a Bacterial Cysteine Dioxygenase
To be Published
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