Author results

1ZJ6
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CRYSTAL STRUCTURE OF HUMAN ARL5
Descriptor:ADP-ribosylation factor-like protein 5, SULFATE ION, GUANOSINE-3'-MONOPHOSPHATE-5'-DIPHOSPHATE
Authors:Wang, Z.X., Shi, L., Liu, J.F., An, X.M., Chang, W.R., Liang, D.C.
Deposit date:2005-04-28
Release date:2005-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:2.0A crystal structure of human ARL5-GDP3'P, a novel member of the small GTP-binding proteins
Biochem.Biophys.Res.Commun., 332, 2005
3LCM
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CRYSTAL STRUCTURE OF SMU.1420 FROM STREPTOCOCCUS MUTANS UA159
Descriptor:Putative oxidoreductase, FLAVIN-ADENINE DINUCLEOTIDE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Wang, Z.X., Su, X.-D.
Deposit date:2010-01-11
Release date:2011-01-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.799 Å)
Cite:Structural and biochemical characterization of MdaB from cariogenic Streptococcus mutans reveals an NADPH-specific quinone oxidoreductase
Acta Crystallogr.,Sect.D, 70, 2014
4OH4
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CRYSTAL STRUCTURE OF BRI1 IN COMPLEX WITH BKI1
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1, BRI1 kinase inhibitor 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Wang, J., Wang, J., Wu, J.W., Wang, Z.X.
Deposit date:2014-01-17
Release date:2014-10-29
Last modified:2014-11-19
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1.
Cell Res., 24, 2014
4Q5J
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CRYSTAL STRUCTURE OF SEMET DERIVATIVE BRI1 IN COMPLEX WITH BKI1
Descriptor:Protein BRASSINOSTEROID INSENSITIVE 1, BRI1 kinase inhibitor 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Wang, J., Wang, J., Chen, L., Wu, J.W., Wang, Z.X.
Deposit date:2014-04-17
Release date:2014-10-29
Method:X-RAY DIFFRACTION (2.772 Å)
Cite:Structural insights into the negative regulation of BRI1 signaling by BRI1-interacting protein BKI1
Cell Res., 2014
4OR9
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CRYSTAL STRUCTURE OF HUMAN CALCINEURIN
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform, Calcineurin subunit B type 1, FE (III) ION, ...
Authors:Li, S.J., Wang, J., Wu, J.W., Wang, Z.X.
Deposit date:2014-02-11
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.23 Å)
Cite:Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published
4ORA
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CRYSTAL STRUCTURE OF A HUMAN CALCINEURIN MUTANT
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform, Calcineurin subunit B type 1, ZINC ION, ...
Authors:Li, S.J., Wang, J., Wu, J.W., Wang, Z.X.
Deposit date:2014-02-11
Release date:2015-05-20
Method:X-RAY DIFFRACTION (2.747 Å)
Cite:Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published
4ORB
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CRYSTAL STRUCTURE OF MOUSE CALCINEURIN
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, Calcineurin subunit B type 1, ZINC ION, ...
Authors:Ma, L., Li, S.J., Wang, J., Wu, J.W., Wang, Z.X.
Deposit date:2014-02-11
Release date:2015-05-20
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (3.108 Å)
Cite:Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published
4ORC
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CRYSTAL STRUCTURE OF MAMMALIAN CALCINEURIN
Descriptor:Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform, Calcineurin subunit B type 1, ZINC ION, ...
Authors:Ma, L., Li, S.J., Wang, J., Wu, J.W., Wang, Z.X.
Deposit date:2014-02-11
Release date:2015-05-20
Last modified:2016-12-21
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Cooperative autoinhibition and multi-level activation mechanisms of calcineurin
To be Published
1SQW
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CRYSTAL STRUCTURE OF KD93, A NOVEL PROTEIN EXPRESSED IN THE HUMAN PRO
Descriptor:Saccharomyces cerevisiae Nip7p homolog
Authors:Liu, J.F., Wang, X.Q., Wang, Z.X., Chen, J.R., Jiang, T., An, X.M., Chan, W.R., Liang, D.C.
Deposit date:2004-03-19
Release date:2005-03-22
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of KD93, a novel protein expressed in human hematopoietic stem/progenitor cells.
J.Struct.Biol., 148, 2004
4F2L
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STRUCTURE OF A REGULATORY DOMAIN OF AMPK
Descriptor:5'-AMP-activated protein kinase catalytic subunit alpha-1, MAGNESIUM ION
Authors:Xin, F.J., Zhang, Y.Y., Wang, J., Wang, Z.X., Wu, J.W.
Deposit date:2012-05-08
Release date:2013-06-26
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Conserved regulatory elements in AMPK
Nature, 498, 2013
4IXP
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CRYSTAL STRUCTURE OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE (MELK)
Descriptor:Maternal embryonic leucine zipper kinase
Authors:Cao, L.S., Wang, J., Wang, Z.X., Wu, J.W.
Deposit date:2013-01-27
Release date:2013-09-11
Method:X-RAY DIFFRACTION (2.749 Å)
Cite:Structural basis for the regulation of maternal embryonic leucine zipper kinase.
Plos One, 8, 2013
5X6G
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CRYSTAL STRUCTURE OF SMAD5-MH1/PALINDROMIC SBE DNA COMPLEX
Descriptor:Mothers against decapentaplegic homolog 5, DNA (5'-D(P*AP*TP*CP*AP*GP*TP*CP*TP*AP*GP*AP*CP*AP*TP*A)-3'), DNA (5'-D(P*GP*TP*AP*TP*GP*TP*CP*TP*AP*GP*AP*CP*TP*GP*A)-3'), ...
Authors:Chai, N., Wang, J., Wang, Z.X., Wu, J.W.
Deposit date:2017-02-21
Release date:2017-03-15
Method:X-RAY DIFFRACTION (3.05 Å)
Cite:Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
5X6H
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CRYSTAL STRUCTURE OF SMAD5-MH1/GC-BRE DNA COMPLEX
Descriptor:Mothers against decapentaplegic homolog 5, DNA (5'-D(P*GP*TP*AP*TP*GP*GP*CP*GP*CP*CP*AP*TP*AP*C)-3'), ZINC ION
Authors:Chai, N., Wang, J., Wang, Z.X., Wu, J.W.
Deposit date:2017-02-22
Release date:2017-03-15
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
5X6M
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CRYSTAL STRUCTURE OF SMAD5-MH1 IN COMPLEX WITH A COMPOSITE DNA SEQUENCE
Descriptor:Mothers against decapentaplegic homolog 5, DNA (5'-D(P*AP*TP*CP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*AP*TP*A)-3'), DNA (5'-D(P*TP*TP*AP*TP*AP*GP*AP*CP*TP*GP*CP*CP*GP*GP*CP*AP*GP*TP*CP*TP*GP*A)-3'), ...
Authors:Chai, N., Wang, J., Wang, Z.X., Wu, J.W.
Deposit date:2017-02-22
Release date:2017-03-15
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural basis for the Smad5 MH1 domain to recognize different DNA sequences.
Nucleic Acids Res., 43, 2015
4MJS
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CRYSTAL STRUCTURE OF A PB1 COMPLEX
Descriptor:Protein kinase C zeta type, Sequestosome-1, 1,2-ETHANEDIOL
Authors:Ren, J., Wang, Z.X., Wu, J.W.
Deposit date:2013-09-04
Release date:2014-08-27
Last modified:2014-10-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural and biochemical insights into the homotypic PB1-PB1 complex between PKC zeta and p62
Sci China Life Sci, 57, 2014
4YR8
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CRYSTAL STRUCTURE OF JNK IN COMPLEX WITH A REGULATOR PROTEIN
Descriptor:Mitogen-activated protein kinase 8, Dual specificity protein phosphatase 16, CHLORIDE ION
Authors:Liu, X., Wang, J., Wu, J.W., Wang, Z.X.
Deposit date:2015-03-14
Release date:2016-03-16
Last modified:2016-03-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation.
Nat Commun, 7, 2016
3DIT
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CRYSTAL STRUCTURE OF MAD MH2 DOMAIN
Descriptor:Protein mothers against dpp
Authors:Hao, R., Wu, J.W., Wang, Z.X.
Deposit date:2008-06-20
Release date:2009-05-12
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of Drosophila Mad MH2 domain.
Acta Crystallogr.,Sect.F, 64, 2008
3PY3
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CRYSTAL STRUCTURE OF PHOSPHORYLATED P38ALPHA MAP KINASE
Descriptor:Mitogen-activated protein kinase 14
Authors:Zhang, Y.Y., Wu, J.W., Wang, Z.X.
Deposit date:2010-12-11
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38{alpha}.
J.Biol.Chem., 286, 2011
3TG1
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CRYSTAL STRUCTURE OF P38ALPHA IN COMPLEX WITH A MAPK DOCKING PARTNER
Descriptor:Mitogen-activated protein kinase 14, Dual specificity protein phosphatase 10
Authors:Zhang, Y.Y., Wu, J.W., Wang, Z.X.
Deposit date:2011-08-17
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38alpha with the MAPK Binding Domain of the Phosphatase MKP5.
Sci.Signal., 4, 2011
3TG3
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CRYSTAL STRUCTURE OF THE MAPK BINDING DOMAIN OF MKP7
Descriptor:Dual specificity protein phosphatase 16, 1,2-ETHANEDIOL
Authors:Zhang, Y.Y., Liu, X., Wu, J.W., Wang, Z.X.
Deposit date:2011-08-17
Release date:2012-03-14
Method:X-RAY DIFFRACTION (2.675 Å)
Cite:A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38alpha with the MAPK Binding Domain of the Phosphatase MKP5.
Sci.Signal., 4, 2011
5YKS
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CRYSTAL STRUCTURE OF SUCROSE NONFERMENTING-RELATED KINASE (SNRK)
Descriptor:SNF-related serine/threonine-protein kinase
Authors:Wang, Y.L., Wang, J., Wu, J.W.
Deposit date:2017-10-16
Release date:2017-11-08
Last modified:2018-01-03
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the kinase and UBA domains of SNRK reveals a distinct UBA binding mode in the AMPK family.
Biochem. Biophys. Res. Commun., 495, 2018
3Q47
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CRYSTAL STRUCTURE OF TPR DOMAIN OF CHIP COMPLEXED WITH PSEUDOPHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.705 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q49
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH HSP70-C PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Hsp70-C peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.543 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
3Q4A
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CRYSTAL STRUCTURE OF THE TPR DOMAIN OF CHIP COMPLEXED WITH PHOSPHORYLATED SMAD1 PEPTIDE
Descriptor:STIP1 homology and U box-containing protein 1, Smad1 peptide
Authors:Wang, L., Chen, L., Wu, J.W.
Deposit date:2010-12-23
Release date:2011-03-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.542 Å)
Cite:Molecular Mechanism of the Negative Regulation of Smad1/5 Protein by Carboxyl Terminus of Hsc70-interacting Protein (CHIP).
J.Biol.Chem., 286, 2011
4LNQ
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CRYSTAL STRUCTURE OF IFI202 HINA DOMAIN IN COMPLEX WITH 20BP DSDNA
Descriptor:Interferon-activable protein 202, 20bp DNA
Authors:Li, H., Wang, Z.-X., Wu, J.-W.
Deposit date:2013-07-12
Release date:2014-01-08
Last modified:2014-02-12
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural mechanism of DNA recognition by the p202 HINa domain: insights into the inhibition of Aim2-mediated inflammatory signalling.
Acta Crystallogr F Struct Biol Commun, 70, 2014
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