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4EGC
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CRYSTAL STRUCTURE OF MBP-FUSED HUMAN SIX1 BOUND TO HUMAN EYA2 EYA DOMAIN
Descriptor:Maltose-binding periplasmic protein, Homeobox protein SIX1 chimera, Eyes absent homolog 2, ...
Authors:Zhao, R., Patrick, A.N.
Deposit date:2012-03-30
Release date:2013-02-27
Last modified:2017-07-26
Method:X-RAY DIFFRACTION (1.994 Å)
Cite:Structure-function analyses of the human SIX1-EYA2 complex reveal insights into metastasis and BOR syndrome.
Nat.Struct.Mol.Biol., 20, 2013
5MU8
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HUMAN TNF-ALPHA IN COMPLEX WITH JNJ525
Descriptor:Tumor necrosis factor, ~{N}4-(phenylmethyl)-~{N}4-[2-[3-(2-piperazin-1-ylpyrimidin-5-yl)phenyl]phenyl]pyrimidine-2,4-diamine
Authors:Blevitt, J.M., Hack, M.D., Herman, K.L., Jackson, P.F., Krawczuk, P.J., Lebsack, A.D., Liu, A.X., Mirzadegan, T., Nelen, M.I., Patrick, A.P., Steinbacher, S., Milla, M.E., Lumb, K.J.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein-Protein Interaction.
J. Med. Chem., 60, 2017