Author results

1WKQ
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CRYSTAL STRUCTURE OF BACILLUS SUBTILIS GUANINE DEAMINASE. THE FIRST DOMAIN-SWAPPED STRUCTURE IN THE CYTIDINE DEAMINASE SUPERFAMILY
Descriptor:Guanine deaminase, ZINC ION, IMIDAZOLE
Authors:Liaw, S.H., Chang, Y.J., Lai, C.T.
Deposit date:2004-06-01
Release date:2004-07-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.17 Å)
Cite:Crystal Structure of Bacillus subtilis Guanine Deaminase: THE FIRST DOMAIN-SWAPPED STRUCTURE IN THE CYTIDINE DEAMINASE SUPERFAMILY
J.Biol.Chem., 279, 2004
2ZJO
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CRYSTAL STRUCTURE OF HEPATITIS C VIRUS NS3 HELICASE WITH A NOVEL INHIBITOR
Descriptor:Genome polyprotein, N-[4-(BIS{4-[(3-SULFOPHENYL)AMINO]PHENYL}METHYLENE)CYCLOHEXA-2,5-DIEN-1-YLIDENE]-4-SULFOBENZENAMINIUM
Authors:Liaw, S.H., Chen, S.J., Hu, C.Y., Chi, W.K., Chu, I.D., Hwang, L.H., Chern, J.W., Chen, D.S.
Deposit date:2008-03-07
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-Based Discovery of Triphenylmethane Derivatives as Novel Inhibitors of Hepatitis C Virus Helicase
To be Published
1VF8
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THE CRYSTAL STRUCTURE OF YM1 AT 1.31 A RESOLUTION
Descriptor:secretory protein
Authors:Liaw, S.H., Tsai, M.L., Chang, N.C.
Deposit date:2004-04-09
Release date:2005-03-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.31 Å)
Cite:The crystal structure of Ym1 at 1.31 A resolution
J.Struct.Biol., 148, 2004
2D5N
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CRYSTAL STRUCTURE OF A BIFUNCTIONAL DEAMINASE AND REDUCTASE INVOLVED IN RIBOFLAVIN BIOSYNTHESIS
Descriptor:Riboflavin biosynthesis protein ribD, ZINC ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Liaw, S.H., Chen, S.J., Chang, Y.C.
Deposit date:2005-11-02
Release date:2005-11-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Crystal structure of a bifunctional deaminase and reductase involved in riboflavin biosynthesis
To be Published
1RJP
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CRYSTAL STRUCTURE OF D-AMINOACYLASE IN COMPLEX WITH 100MM CUCL2
Descriptor:D-aminoacylase, ACETATE ION, ZINC ION, ...
Authors:Lai, W.L., Chou, L.Y., Ting, C.Y., Tsai, Y.C., Liaw, S.H.
Deposit date:2003-11-20
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
1RJQ
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THE CRYSTAL STRUCTURE OF THE D-AMINOACYLASE MUTANT D366A
Descriptor:D-aminoacylase, ACETATE ION, ZINC ION
Authors:Lai, W.L., Chou, L.Y., Ting, C.Y., Tsai, Y.C., Liaw, S.H.
Deposit date:2003-11-20
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
1RJR
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THE CRYSTAL STRUCTURE OF THE D-AMINOACYLASE D366A MUTANT IN COMPLEX WITH 100MM ZNCL2
Descriptor:D-aminoacylase, ACETATE ION, ZINC ION
Authors:Lai, W.L., Chou, L.Y., Ting, C.Y., Tsai, Y.C., Liaw, S.H.
Deposit date:2003-11-20
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
1RK5
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THE D-AMINOACYLASE MUTANT D366A IN COMPLEX WITH 100MM CUCL2
Descriptor:D-aminoacylase, ACETATE ION, ZINC ION, ...
Authors:Lai, W.L., Chou, L.Y., Ting, C.Y., Tsai, Y.C., Liaw, S.H.
Deposit date:2003-11-20
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
1RK6
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THE ENZYME IN COMPLEX WITH 50MM CDCL2
Descriptor:D-aminoacylase, ACETATE ION, ZINC ION, ...
Authors:Lai, W.L., Chou, L.Y., Ting, C.Y., Tsai, Y.C., Liaw, S.H.
Deposit date:2003-11-20
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.43 Å)
Cite:The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
1V51
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THE FUNCTIONAL ROLE OF THE BINUCLEAR METAL CENTER IN D-AMINOACYLASE. ONE-METAL ACTIVATION AND SECOND-METAL ATTENUATION
Descriptor:D-aminoacylase, ACETATE ION, ZINC ION
Authors:Lai, W.L., Chou, L.Y., Ting, C.Y., Tsai, Y.C., Liaw, S.H.
Deposit date:2003-11-20
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:The functional role of the binuclear metal center in D-aminoacylase: one-metal activation and second-metal attenuation.
J.Biol.Chem., 279, 2004
1V4Y
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THE FUNCTIONAL ROLE OF THE BINUCLEAR METAL CENTER IN D-AMINOACYLASE. ONE-METAL ACTIVATION AND SECOND-METAL ATTENUATION
Descriptor:D-aminoacylase, ACETATE ION, ZINC ION
Authors:Lai, W.L., Chou, L.Y., Ting, C.Y., Tsai, Y.C., Liaw, S.H.
Deposit date:2003-11-20
Release date:2004-04-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The Functional Role of the Binuclear Metal Center in D-Aminoacylase: ONE-METAL ACTIVATION AND SECOND-METAL ATTENUATION.
J.Biol.Chem., 279, 2004
3EX8
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COMPLEX STRUCTURE OF BACILLUS SUBTILIS RIBG REDUCTION MECHANISM IN RIBOFLAVIN BIOSYNTHESIS
Descriptor:Riboflavin biosynthesis protein ribD, ZINC ION, [(2R,3S,4R,5E)-5-[(5-amino-2,6-dioxo-3H-pyrimidin-4-yl)imino]-2,3,4-trihydroxy-pentyl] dihydrogen phosphate
Authors:Chen, S.C., Lin, Y.H., Yu, H.C., Liaw, S.H.
Deposit date:2008-10-16
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Complex structure of Bacillus subtilis RibG: the reduction mechanism during riboflavin biosynthesis.
J.Biol.Chem., 284, 2009
2B3Z
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CRYSTAL STRUCTURE OF A BIFUNCTIONAL DEAMINASE AND REDUCTASE INVOLVED IN RIBOFLAVIN BIOSYNTHESIS
Descriptor:Riboflavin biosynthesis protein ribD, ZINC ION
Authors:Chen, S.J., Chang, Y.C., Liaw, S.H.
Deposit date:2005-09-22
Release date:2005-11-29
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.41 Å)
Cite:Crystal structure of a bifunctional deaminase and reductase involved in riboflavin biosynthesis
To be Published
4DNS
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CRYSTAL STRUCTURE OF BERMUDA GRASS ISOALLERGEN BG60 PROVIDES INSIGHT INTO THE VARIOUS CROSS-ALLERGENICITY OF THE POLLEN GROUP 4 ALLERGENS
Descriptor:FAD-linked oxidoreductase BG60, FLAVIN-ADENINE DINUCLEOTIDE, N-ACETYL-D-GLUCOSAMINE
Authors:Huang, T.H., Peng, H.J., Su, S.N., Liaw, S.H.
Deposit date:2012-02-08
Release date:2012-12-05
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Various cross-reactivity of the grass pollen group 4 allergens: crystallographic study of the Bermuda grass isoallergen Cyn d 4.
Acta Crystallogr.,Sect.D, 68, 2012
4G3M
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COMPLEX STRUCTURE OF BACILLUS SUBTILIS RIBG: THE DEAMINATION PROCESS IN RIBOFLAVIN BIOSYNTHESIS
Descriptor:Riboflavin biosynthesis protein RibD, ZINC ION, [(2R,3S,4S,5E)-5-[[5-azanyl-2,4-bis(oxidanylidene)-1H-pyrimidin-6-yl]imino]-2,3,4-tris(oxidanyl)pentyl] dihydrogen phosphate, ...
Authors:Chen, S.C., Shen, C.Y., Yen, T.M., Yu, H.C., Chang, T.H., Lai, W.L., Liaw, S.H.
Deposit date:2012-07-15
Release date:2013-02-20
Method:X-RAY DIFFRACTION (2.56 Å)
Cite:Evolution of vitamin B(2) biosynthesis: eubacterial RibG and fungal Rib2 deaminases.
Acta Crystallogr.,Sect.D, 69, 2013
4TVU
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CRYSTAL STRUCTURE OF TREHALOSE SYNTHASE FROM DEINOCOCCUS RADIODURANS REVEALS A CLOSED CONFORMATION FOR CATALYSIS OF THE INTRAMOLECULAR ISOMERIZATION
Descriptor:Trehalose synthase, CALCIUM ION, MAGNESIUM ION, ...
Authors:Wang, Y.L., Chow, S.Y., Lin, Y.T., Liaw, S.H.
Deposit date:2014-06-28
Release date:2014-12-17
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of trehalose synthase from Deinococcus radiodurans reveal that a closed conformation is involved in catalysis of the intramolecular isomerization.
Acta Crystallogr.,Sect.D, 70, 2014
4WF7
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CRYSTAL STRUCTURES OF TREHALOSE SYNTHASE FROM DEINOCOCCUS RADIODURANS REVEAL THAT A CLOSED CONFORMATION IS INVOLVED IN THE INTRAMOLECULAR ISOMERIZATION CATALYSIS
Descriptor:Trehalose synthase, CALCIUM ION, MAGNESIUM ION, ...
Authors:Wang, Y.L., Chow, S.Y., Lin, Y.T., Hsieh, Y.C., Lee, G.C., Liaw, S.H.
Deposit date:2014-09-13
Release date:2014-12-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structures of trehalose synthase from Deinococcus radiodurans reveal that a closed conformation is involved in catalysis of the intramolecular isomerization.
Acta Crystallogr.,Sect.D, 70, 2014
5GTW
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THE N253R MUTANT STRUCTURES OF TREHALOSE SYNTHASE FROM DEINOCOCCUS RADIODURANS DISPLAY TWO DIFFERENT ACTIVE-SITE CONFORMATIONS
Descriptor:Trehalose synthase, CALCIUM ION, MAGNESIUM ION, ...
Authors:Chow, S.Y., Wei, Y.J., Liaw, S.H.
Deposit date:2016-08-23
Release date:2017-08-30
Method:X-RAY DIFFRACTION (2.93 Å)
Cite:The N253R mutant structures of trehalose synthase from Deinococcus radiodurans display two different active-site conformations
To Be Published
5XUX
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CRYSTAL STRUCTURE OF RIB7 FROM METHANOSARCINA MAZEI
Descriptor:Conserved protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yeh, T.M., Chen, S.C., Chang, T.H., Huang, M.F., Liaw, S.H.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.
Biochem. Biophys. Res. Commun., 503, 2018
5XV0
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CRYSTAL STRUCTURE OF RIB7 MUTANT D33N FROM METHANOSARCINA MAZEI
Descriptor:Conserved protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yeh, T.M., Chen, S.C., Chang, T.H., Huang, M.F., Liaw, S.H.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.
Biochem. Biophys. Res. Commun., 503, 2018
5XV2
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CRYSTAL STRUCTURE OF RIB7 MUTANT D33A FROM METHANOSARCINA MAZEI
Descriptor:Conserved protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yeh, T.M., Chen, S.C., Chang, T.H., Huang, M.F., Liaw, S.H.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2 Å)
Cite:Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.
Biochem. Biophys. Res. Commun., 503, 2018
5XV5
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CRYSTAL STRUCTURE OF RIB7 MUTANT S88E FROM METHANOSARCINA MAZEI
Descriptor:Conserved protein
Authors:Yeh, T.M., Chen, S.C., Chang, T.H., Huang, M.F., Liaw, S.H.
Deposit date:2017-06-26
Release date:2018-07-04
Last modified:2019-01-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.
Biochem. Biophys. Res. Commun., 503, 2018
5YKB
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THE N253F MUTANT STRUCTURE OF TREHALOSE SYNTHASE FROM DEINOCOCCUS RADIODURANS REVEALS AN OPEN ACTIVE-SITE CONFORMATION
Descriptor:Trehalose synthase, CALCIUM ION, MAGNESIUM ION
Authors:Chow, S.Y., Hsieh, Y.C., Liaw, S.H.
Deposit date:2017-10-13
Release date:2017-10-25
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.76 Å)
Cite:The N253F mutant structure of trehalose synthase from Deinococcus radiodurans reveals an open active-site topology
Acta Crystallogr F Struct Biol Commun, 73, 2017
1LGR
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INTERACTIONS OF NUCLEOTIDES WITH FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM
Descriptor:GLUTAMINE SYNTHETASE, MANGANESE (II) ION, ADENOSINE MONOPHOSPHATE
Authors:Liaw, S.-H., Eisenberg, D.
Deposit date:1994-08-05
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Interactions of nucleotides with fully unadenylylated glutamine synthetase from Salmonella typhimurium.
Biochemistry, 33, 1994
2LGS
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FEEDBACK INHIBITION OF FULLY UNADENYLYLATED GLUTAMINE SYNTHETASE FROM SALMONELLA TYPHIMURIUM BY GLYCINE, ALANINE, AND SERINE
Descriptor:GLUTAMINE SYNTHETASE, MANGANESE (II) ION, GLUTAMIC ACID
Authors:Liaw, S.-H., Eisenberg, D.
Deposit date:1994-08-05
Release date:1994-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Feedback inhibition of fully unadenylylated glutamine synthetase from Salmonella typhimurium by glycine, alanine, and serine.
Proc.Natl.Acad.Sci.USA, 90, 1993
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