Author results

110D
  • Download 110d
  • View 110d
Molmil generated image of 110d
ANTHRACYCLINE-DNA INTERACTIONS AT UNFAVOURABLE BASE BASE-PAIR TRIPLET-BINDING SITES: STRUCTURES OF D(CGGCCG)/DAUNOMYCIN AND D(TGGCCA)/ADRIAMYCIN COMPL
Descriptor:DNA (5'-D(*CP*GP*GP*CP*CP*G)-3'), DAUNOMYCIN
Authors:Leonard, G.A., Hambley, T.W., McAuley-Hecht, K., Brown, T., Hunter, W.N.
Deposit date:1993-01-21
Release date:1993-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes.
Acta Crystallogr.,Sect.D, 49, 1993
119D
  • Download 119d
  • View 119d
Molmil generated image of 119d
CRYSTAL AND MOLECULAR STRUCTURE OF D(CGTAGATCTACG) AT 2.25 ANGSTROMS RESOLUTION
Descriptor:DNA (5'-D(*CP*GP*TP*AP*GP*AP*TP*CP*TP*AP*CP*G)-3'), MAGNESIUM ION
Authors:Leonard, G.A., Hunter, W.N.
Deposit date:1993-04-14
Release date:1993-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal and molecular structure of d(CGTAGATCTACG) at 2.25 A resolution.
J.Mol.Biol., 234, 1993
150D
  • Download 150d
  • View 150d
Molmil generated image of 150d
GUANINE.1,N6-ETHENOADENINE BASE-PAIRS IN THE CRYSTAL STRUCTURE OF D(CGCGAATT(EDA)GCG)
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(EDA)P*GP*CP*G)-3'), MAGNESIUM ION
Authors:Leonard, G.A., McAuley-Hecht, K.E., Gibson, N.J., Brown, T., Watson, W.P., Hunter, W.N.
Deposit date:1993-12-02
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Guanine-1,N6-ethenoadenine base pairs in the crystal structure of d(CGCGAATT(epsilon dA)GCG).
Biochemistry, 33, 1994
157D
  • Download 157d
  • View 157d
Molmil generated image of 157d
CRYSTAL AND MOLECULAR STRUCTURE OF R(CGCGAAUUAGCG): AN RNA DUPLEX CONTAINING TWO G(ANTI).A(ANTI) BASE-PAIRS
Descriptor:RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3')
Authors:Leonard, G.A., McAuley-Hecht, K.E., Ebel, S., Lough, D.M., Brown, T., Hunter, W.N.
Deposit date:1994-02-01
Release date:1994-05-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal and molecular structure of r(CGCGAAUUAGCG): an RNA duplex containing two G(anti).A(anti) base pairs.
Structure, 2, 1994
184D
  • Download 184d
  • View 184d
Molmil generated image of 184d
SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION
Descriptor:DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3'), MAGNESIUM ION
Authors:Leonard, G.A., Zhang, S., Peterson, M.R., Harrop, S.J., Helliwell, J.R., Cruse, W.B.T., Langlois D'Estaintot, B., Kennard, O., Brown, T., Hunter, W.N.
Deposit date:1994-08-10
Release date:1995-07-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution.
Structure, 3, 1995
1D27
  • Download 1d27
  • View 1d27
Molmil generated image of 1d27
HIGH-RESOLUTION STRUCTURE OF A MUTAGENIC LESION IN DNA
Descriptor:DNA (5'-D(*CP*GP*CP*(6OG)P*AP*AP*TP*TP*TP*GP*CP*G)-3')
Authors:Leonard, G.A., Thomson, J., Watson, W.P., Brown, T.
Deposit date:1991-04-22
Release date:1992-04-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution structure of a mutagenic lesion in DNA.
Proc.Natl.Acad.Sci.USA, 87, 1990
1D54
  • Download 1d54
  • View 1d54
Molmil generated image of 1d54
ANTHRACYCLINE BINDING TO DNA: HIGH RESOLUTION STRUCTURE OF D(TGTACA) COMPLEXED WITH 4'-EPIADRIAMYCIN
Descriptor:DNA (5'-D(*TP*GP*TP*AP*CP*A)-3'), 4'-EPIDOXORUBICIN
Authors:Leonard, G.A., Brown, T., Hunter, W.N.
Deposit date:1992-01-06
Release date:1993-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Anthracycline binding to DNA. High-resolution structure of d(TGTACA) complexed with 4'-epiadriamycin.
Eur.J.Biochem., 204, 1992
1D75
  • Download 1d75
  • View 1d75
Molmil generated image of 1d75
CONFORMATION OF THE GUANINE.8-OXOADENINE BASE PAIRS IN THE CRYSTAL STRUCTURE OF D(CGCGAATT(O8A)GCG)
Descriptor:DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(A38)P*GP*CP*G)-3')
Authors:Leonard, G.A., Guy, A., Brown, T., Teoule, R., Hunter, W.N.
Deposit date:1992-05-07
Release date:1993-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG).
Biochemistry, 31, 1992
1D81
  • Download 1d81
  • View 1d81
Molmil generated image of 1d81
THE CONFORMATIONAL VARIABILITY OF AN ADENOSINE. INOSINE BASE-PAIR IN A SYNTHETIC DNA DODECAMER
Descriptor:DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*IP*GP*CP*G)-3')
Authors:Leonard, G.A., Booth, E.D., Hunter, W.N., Brown, T.
Deposit date:1992-07-07
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The conformational variability of an adenosine.inosine base-pair in a synthetic DNA dodecamer.
Nucleic Acids Res., 20, 1992
1DA9
  • Download 1da9
  • View 1da9
Molmil generated image of 1da9
ANTHRACYCLINE-DNA INTERACTIONS AT UNFAVOURABLE BASE BASE-PAIR TRIPLET-BINDING SITES: STRUCTURES OF D(CGGCCG)/DAUNOMYCIN AND D(TGGCCA)/ADRIAMYCIN COMPL
Descriptor:DNA (5'-D(*TP*GP*GP*CP*CP*A)-3'), DOXORUBICIN
Authors:Leonard, G.A., Hambley, T.W., McAuley-Hecht, K., Brown, T., Hunter, W.N.
Deposit date:1993-01-21
Release date:1993-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes.
Acta Crystallogr.,Sect.D, 49, 1993
1O6J
  • Download 1o6j
  • View 1o6j
Molmil generated image of 1o6j
TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY SULPHUR PHASING
Descriptor:TRYPAREDOXIN II
Authors:Leonard, G.A., Micossi, E., Hunter, W.N.
Deposit date:2002-10-04
Release date:2002-11-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures
Acta Crystallogr.,Sect.D, 58, 2002
1O81
  • Download 1o81
  • View 1o81
Molmil generated image of 1o81
TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY SULPHUR PHASING
Descriptor:TRYPAREDOXIN II, SULFATE ION
Authors:Leonard, G.A., Micossi, E., Hunter, W.N.
Deposit date:2002-11-21
Release date:2002-12-19
Last modified:2017-07-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures
Acta Crystallogr.,Sect.D, 58, 2002
1OC8
  • Download 1oc8
  • View 1oc8
Molmil generated image of 1oc8
TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY MR
Descriptor:TRYPAREDOXIN II, SULFATE ION
Authors:Leonard, G.A., Micossi, E., Hunter, W.N.
Deposit date:2003-02-07
Release date:2003-04-02
Last modified:2018-10-24
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1OC9
  • Download 1oc9
  • View 1oc9
Molmil generated image of 1oc9
TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY MR
Descriptor:TRYPAREDOXIN II
Authors:Leonard, G.A., Micossi, E., Hunter, W.N.
Deposit date:2003-02-07
Release date:2003-03-20
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1N2S
  • Download 1n2s
  • View 1n2s
Molmil generated image of 1n2s
CRYSTAL STRUCTURE OF DTDP-6-DEOXY-L-LYXO-4-HEXULOSE REDUCTASE (RMLD) IN COMPLEX WITH NADH
Descriptor:dTDP-glucose oxidoreductase, MAGNESIUM ION, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ...
Authors:Blankenfeldt, W., Kerr, I.D., Giraud, M.F., Mcmiken, H.J., Leonard, G.A., Whitfield, C., Messner, P., Graninger, M., Naismith, J.H.
Deposit date:2002-10-24
Release date:2002-11-01
Last modified:2013-11-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Variation on a Theme of SDR. dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg(2+)-Dependent Dimerization Mode
Structure, 10, 2002
111D
  • Download 111d
  • View 111d
Molmil generated image of 111d
CRYSTAL STRUCTURE AND STABILITY OF A DNA DUPLEX CONTAINING A(ANTI).G(SYN) BASE-PAIRS
Descriptor:DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*GP*GP*CP*G)-3')
Authors:Brown, T., Leonard, G.A., Booth, E.D., Chambers, J.
Deposit date:1993-01-04
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure and stability of a DNA duplex containing A(anti).G(syn) base-pairs.
J.Mol.Biol., 207, 1989
133D
  • Download 133d
  • View 133d
Molmil generated image of 133d
THE CRYSTAL STRUCTURE OF N4-METHYLCYTOSINE.GUANOSIN BASE-PAIRS IN THE SYNTHETIC HEXANUCLEOTIDE D(CGCGM(4)CG)
Descriptor:DNA (5'-D(*CP*GP*CP*GP*(C34)P*G)-3')
Authors:Cervi, A.R., Guy, A., Leonard, G.A., Teoule, R., Hunter, W.N.
Deposit date:1993-07-29
Release date:1994-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of N4-methylcytosine.guanosine base-pairs in the synthetic hexanucleotide d(CGCGm4CG).
Nucleic Acids Res., 21, 1993
178D
  • Download 178d
  • View 178d
Molmil generated image of 178d
CRYSTAL STRUCTURE OF A DNA DUPLEX CONTAINING 8-HYDROXYDEOXYGUANINE.ADENINE BASE-PAIRS
Descriptor:DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*(8OG)P*GP*CP*G)-3')
Authors:McAuley-Hecht, K.E., Leonard, G.A., Gibson, N.J., Thomson, J.B., Watson, W.P., Hunter, W.N., Brown, T.
Deposit date:1994-05-19
Release date:1994-10-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs.
Biochemistry, 33, 1994
1D4R
  • Download 1d4r
  • View 1d4r
Molmil generated image of 1d4r
29-MER FRAGMENT OF HUMAN SRP RNA HELIX 6
Descriptor:29-MER OF MODIFIED SRP RNA HELIX 6, MAGNESIUM ION
Authors:Wild, K., Weichenrieder, O., Leonard, G.A., Cusack, S.
Deposit date:1999-10-05
Release date:1999-12-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The 2 A structure of helix 6 of the human signal recognition particle RNA
Structure Fold.Des., 7, 1999
1D90
  • Download 1d90
  • View 1d90
Molmil generated image of 1d90
REFINED CRYSTAL STRUCTURE OF AN OCTANUCLEOTIDE DUPLEX WITH I.T MISMATCHED BASE PAIRS
Descriptor:DNA (5'-D(*GP*GP*IP*GP*CP*TP*CP*C)-3')
Authors:Cruse, W.B.T., Aymani, J., Kennard, O., Brown, T., Jack, A.G.C., Leonard, G.A.
Deposit date:1992-10-17
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Refined crystal structure of an octanucleotide duplex with I.T. mismatched base pairs.
Nucleic Acids Res., 17, 1989
1GYN
  • Download 1gyn
  • View 1gyn
Molmil generated image of 1gyn
CLASS II FRUCTOSE 1,6-BISPHOSPHATE ALDOLASE WITH CADMIUM (NOT ZINC) IN THE ACTIVE SITE
Descriptor:FRUCTOSE-BISPHOSPHATE ALDOLASE II, CADMIUM ION
Authors:Hall, D.R., Kemp, L.E., Leonard, G.A., Berry, A., Hunter, W.N.
Deposit date:2002-04-27
Release date:2003-02-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Organization of Divalent Cations in the Active Site of Cadmium Escherichia Coli Fructose 1,6-Bisphosphate Aldolase
Acta Crystallogr.,Sect.D, 59, 2003
1H76
  • Download 1h76
  • View 1h76
Molmil generated image of 1h76
THE CRYSTAL STRUCTURE OF DIFERRIC PORCINE SERUM TRANSFERRIN
Descriptor:SEROTRANSFERRIN, CARBONATE ION, FE (III) ION, ...
Authors:Hall, D.R., Hadden, J.M., Leonard, G.A., Bailey, S., Neu, M., Winn, M., Lindley, P.F.
Deposit date:2001-07-03
Release date:2002-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The Crystal and Molecular Structures of Diferric Porcine and Rabbit Serum Transferrins at Resolutions of 2.15 And 2.60A, Respectively
Acta Crystallogr.,Sect.D, 58, 2002
1I4U
  • Download 1i4u
  • View 1i4u
Molmil generated image of 1i4u
THE C1 SUBUNIT OF ALPHA-CRUSTACYANIN
Descriptor:CRUSTACYANIN, SULFATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL
Authors:Gordon, E.J., Leonard, G.A., McSweeney, S., Zagalsky, P.F.
Deposit date:2001-02-23
Release date:2001-09-19
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.15 Å)
Cite:The C1 subunit of alpha-crustacyanin: the de novo phasing of the crystal structure of a 40 kDa homodimeric protein using the anomalous scattering from S atoms combined with direct methods.
Acta Crystallogr.,Sect.D, 57, 2001
1JNF
  • Download 1jnf
  • View 1jnf
Molmil generated image of 1jnf
RABBIT SERUM TRANSFERRIN AT 2.6 A RESOLUTION.
Descriptor:serotransferrin, CARBONATE ION, FE (III) ION, ...
Authors:Hall, D.R., Hadden, J.M., Leonard, G.A., Bailey, S., Neu, M., Winn, M., Lindley, P.F.
Deposit date:2001-07-24
Release date:2001-08-01
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal and molecular structures of diferric porcine and rabbit serum transferrins at resolutions of 2.15 and 2.60 A, respectively.
Acta Crystallogr.,Sect.D, 58, 2002
1UTB
  • Download 1utb
  • View 1utb
Molmil generated image of 1utb
DNTR FROM BURKHOLDERIA SP. STRAIN DNT
Descriptor:LYSR-TYPE REGULATORY PROTEIN, GLYCEROL, ACETATE ION
Authors:Smirnova, I.A., Dian, C., Leonard, G.A., McSweeney, S., Birse, D., Brzezinski, P.
Deposit date:2003-12-05
Release date:2004-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Development of a Bacterial Biosensor for Nitrotoluenes: The Crystal Structure of the Transcriptional Regulator Dntr
J.Mol.Biol., 340, 2004